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Psychiatry General

Prevalence of complicated grief and related factors in elderly individuals in Sabzevar City, Iran.

Jul 27, 2020

Although often undiagnosed and untreated, prolonged grief and its conversion to complicated grief (CG) can lead to functional impairment. Given the impact of CG on mortality and quality of life in eld...

Involvement of the endogenous opioid system in the beneficial influence of physical exercise on amphetamine-induced addiction parameters.

Jul 27, 2020

Psychostimulant drugs addiction is a chronic public health problem and individuals remain susceptible to relapses increasing public expenses even after withdrawal and treatment. Our research group has...

Nalfurafine modulates the reinforcing effects of oxycodone in male and female adolescent C57BL/6J mice.

Jul 27, 2020

Addiction to prescription opioid, such as oxycodone, has affected millions of adolescents and young adults. Kappa opioid receptor (KOP-r) agonist can counterbalance the euphoria effects of mu opioid a...

Prenatal Methamphetamine Exposure and Adverse Neonatal Outcomes: A Nationwide Cohort Study.

Jul 27, 2020

There is limited knowledge on the adverse outcomes in newborns after maternal methamphetamine (MA) use during pregnancy.To compare neonatal outcomes in newborns exposed to MA with the newborns of opio...

Lentiviral delivery of human erythropoietin attenuates hippocampal atrophy and improves cognition in the R6/2 mouse model of Huntington's disease.

Jul 27, 2020

Huntington's disease (HD) is an incurable neurodegenerative disorder caused by a trinucleotide (CAG) repeat expansion in the huntingtin gene (HTT). The R6/2 transgenic mouse model of HD expresses exon...

Reproducibility and reaction time of swallowing as markers of dysphagia in parkinsonian syndromes.

Jul 27, 2020

To investigate reproducibility and reaction time of oropharyngeal swallowing in patients with Parkinson's disease (PD) and atypical parkinsonisms (APs).We enrolled 19 patients with PD, 30 with APs, an...

Specific cortical and subcortical alterations for reactive and proactive aggression in children and adolescents with disruptive behavior.

Jul 27, 2020

Maladaptive aggression, as present in conduct disorder (CD) and, to a lesser extent, oppositional defiant disorder (ODD), has been associated with structural alterations in various brain regions, such...

Prognostic value of Cardiac Biomarkers in COVID-19 Infection: A Meta-analysis.

Jul 27, 2020

Multiple Biomarkers have recently been shown to be elevated in COVID-19, a respiratory infection with multi-organ dysfunction; however, information regarding the prognostic value of cardiac biomarker...

Computer based patient education is non-inferior to nurse counselling prior to colonoscopy, a multicenter randomized controlled trial.

Jul 27, 2020

Optimal patient education prior to colonoscopy improves adherence to instructions for bowel preparation and leads to cleaner colons. We developed computer based education (CBE) supported by video and ...

Effects of pharmacologic and nonpharmacologic interventions on menopause-related quality of life: a pooled analysis of individual participant data from four MsFLASH trials.

Jul 27, 2020

The Menopause Strategies: Finding Lasting Answers for Symptoms and Health network conducted three randomized clinical trials (RCTs) testing six interventions treating vasomotor symptoms (VMS), and als...

Lasting consequences of concussion on the aging brain: findings from the Baltimore Longitudinal Study of Aging.

Jul 27, 2020

Studies suggest that concussions may be related to increased risk of neurodegenerative diseases, such as Chronic Traumatic Encephalopathy and Alzheimer's Disease. Most neuroimaging studies show effect...

Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis.

Jul 27, 2020

Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Cigarette smoke is a major etiological risk factor that has...

Interventions for the management of obesity in people with bipolar disorder.

Jul 23, 2020

Bipolar disorder is one of the most common serious mental illnesses, affecting approximately 60 million people worldwide. Characterised by extreme alterations in mood, cognition, and behaviour, bipola...

Window to His World: Using a Patient's YouTube Channel to Help Diagnose Chronic Mania.

Jul 23, 2020

Although chronic mania has been investigated, with several case reports and systematic retrospective cohort studies in the literature, it not a widely recognized entity. No specific definition for chr...

Commentary on "Window to His World: Using a Patient's YouTube Channel to Help Diagnose Chronic Mania".

Jul 23, 2020

Although chronic mania has been investigated, with several case reports and systematic retrospective cohort studies in the literature, it not a widely recognized entity. No specific definition for chr...

A single episode of early-life status epilepticus impacts neonatal ultrasonic vocalization behavior in the Fmr1 knockout mouse.

Jul 23, 2020

Fragile X syndrome (FXS) is a genetic disorder caused by a trinucleotide (CGG) expansion mutation in the Fmr1 gene located on the X chromosome. It is characterized by hyperactivity, increased anxiety,...

Protecting Breastfeeding during the COVID-19 Pandemic.

Jul 23, 2020

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has impacted all patient populations including pregnant mothers. There is an incomplete understanding of SARS-CoV-2 pathogenes...

Continued Prescribing of Periprocedural Codeine and Tramadol to Children after a Black Box Warning.

Jul 23, 2020

Codeine and tramadol are commonly used analgesics in surgery. In 2013, the Food and Drug Administration (FDA) issued a contraindication to the use of codeine in tonsillectomy and adenoidectomy patient...

The Efficacy and Safety of Transversus Abdominis Plane Blocks After Open Cholecystectomy in Low- and Middle-Income Countries.

Jul 23, 2020

Postoperative pain management is challenging in low- and middle-income countries (LMICs). This study assesses the safety and efficacy of transversus abdominis plane (TAP) blocks as an adjunct for post...

Pharmacokinetics and Safety of Mitragynine in Beagle Dogs.

Jul 23, 2020

Mitragynine is the most abundant psychoactive alkaloid derived from the leaves of (kratom), a tropical plant indigenous to regions of Southeast Asia. Mitragynine displays a moderate affinity to opioi...

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