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Psychiatry General

Reduced Functional Connectivity of the Brain During Working Memory in Methamphetamine Use Disorder

May 04, 2023

The following is a summary of “Reduced neural functional connectivity during working memory performance in methamphetamine use disorder,” published in the February 2023 issue of Drug and Alcohol D...

Tracking the Trail of Opioids and Benzodiazepines: Kentucky's Prescription Monitoring Program

May 03, 2023

The following is a summary of “Mandatory prescription drug monitoring programs and overlapping prescriptions of opioids and benzodiazepines: Evidence from Kentucky," published in the February  2023...

Exploring the Therapeutic Effects of Smoked Cannabis on Polysubstance Use

May 02, 2023

The following is a summary of “Smoked cannabis reduces peak cocaine plasma levels and subjective effects in a controlled drug administration study of polysubstance use in men,” published in the Fe...

The Modulation of Fentanyl-depressed Respiration by Amphetamines in a Bidirectional Manner

May 01, 2023

The following is a summary of "Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner," published in the February 2023 issue of Drug and Alcohol Dependence by Elder et al. ...

Frequency of antidepressant use and clinical characteristics of children and adolescents undergoing polysomnography: an observational study.

May 01, 2023

Antidepressants are increasingly used in children for various psychiatric disorders but also for sleep disorders such as insomnia; however, it is currently unknown how many children undergoing polysom...

Smoking status ameliorates cholinergic impairments in cortical inhibition in patients with schizophrenia.

May 01, 2023

Rationale Modulation of cortical excitability, in particular inhibition, is impaired in patients with schizophrenia. Chronic nicotine consumption, which is prevalent in this group, has been shown to a...

Analysis of Appendicitis Cases in the Japanese Adverse Drug Event Report (JADER) Database.

May 01, 2023

Appendicitis is one of the most common abdominal surgical emergencies worldwide; however, its causes remain poorly understood. The Japanese Adverse Drug Event Report (JADER) database is a spontaneous ...

Physicochemical Properties of Branded and Generic Infusion Fluid Preparations: Results of a Comparative Experimental Study on Type 2 Hypotonic Infusion Fluid.

May 01, 2023

In Japan, four different types of hypotonic infusion fluids, namely, types 1-4, are available and used depending on the patient's condition. Although branded and generic products for each type of hypo...

Effects of medial prefrontal transcranial alternating current stimulation on neural activity and connectivity in people with Huntington's disease and neurotypical controls.

May 01, 2023

We investigated the effects of transcranial alternating current stimulation (tACS) targeted to the medial prefrontal cortex (mPFC) on resting electroencephalographic (EEG) indices of oscillatory power...

Sublingual Dexmedetomidine for the Treatment of Agitation in Patients with Schizophrenia and Bipolar Disorder.

May 01, 2023

Acute agitation is common amongst individuals with bipolar disorder and schizophrenia and represents a medical emergency. Commonly used medications for agitation, such as benzodiazepines and antipsych...

A systematic review of manic/hypomanic and depressive switches in patients with bipolar disorder in naturalistic settings: The role of antidepressant and antipsychotic drugs.

May 01, 2023

The present systematic review was aimed at critically summarizing the evidence about treatment-emergent manic/hypomanic and depressive switches during the course of bipolar disorder (BD). A systematic...

Uncovering the brain-wide pattern of synaptic input to vasopressin-expressing neurons in the paraventricular nucleus of the hypothalamus.

May 01, 2023

Arginine vasopressin (AVP) is a neuropeptide critical for the mammalian stress response and social behavior. AVP produced in the hypothalamus regulates water osmolality and vasoconstriction in the bod...

Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders.

May 01, 2023

Physical health and chronic medical comorbidities are underestimated, inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide characterization of brain and body health in ne...

Navigating the Gender Gap: Genetic Influences on Depression and Alcohol Consumption

Apr 24, 2023

The following is a summary of “Genetic predisposition to major depressive disorder differentially impacts alcohol consumption and high-risk drinking situations in men and women with alcohol use diso...

Sleep Problems, Suicidal Ideation, and Psychopathology in First-Episode Psychosis.

Apr 24, 2023

Insomnia occurs frequently in the clinical course of schizophrenia. A growing literature has found associations between insomnia, suicidal ideation and behavior, and psychopathology in schizophrenia. ...

Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells.

Apr 24, 2023

Clozapine is usually considered as the last resort for treatment-resistant schizophrenia (TRS). However, it shows limited efficacy in cognition improvement. Moreover, the metabolic side effects induce...

Catatonia and ECT across the lifespan.

Apr 24, 2023

Electroconvulsive therapy (ECT) is a safe and effective treatment for catatonia with high response rates. Although empirical data suggest that tolerability and efficacy are at least as good as in adul...

Behavioral Activation Disseminated by Non-Mental Health Professionals, Paraprofessionals, and Peers: A Systematic Review.

Apr 24, 2023

There is a striking disparity between the number of individuals with significant mental health concerns and those who are able to access care globally. One promising solution to expanding the mental h...

Atypical antipsychotic-induced mania: A systematic review and meta-analysis.

Apr 24, 2023

The possibility of atypical antipsychotics (AA) to induce manic symptoms has been raised by several articles. The objective of this study was to describe whether exposure to AA may induce mania in moo...

Decreased serum allopregnanolone and progesterone levels in male patients with bipolar disorder and their effects on cognitive functions.

Apr 24, 2023

The progression of bipolar disorder (BD) is characterized by recurrent episodes of depression, mania, and hypomania, thus affecting the daily functionality of individuals. Previous studies have shown ...

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