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Psychiatry General

Nitric Oxide Stimulates Acute Pancreatitis Pain via Activating the NF-B Signaling Pathway and Inhibiting the Kappa Opioid Receptor.

May 28, 2020

Pain is the most important clinical feature of acute pancreatitis (AP); however, its specific mechanism is currently unclear. In this study, we showed that AP caused an increase in nitric oxide (NO) s...

Reducing Opioid Overprescribing by Educating, Monitoring and Collaborating with Clinicians: A Quality Improvement Study.

May 28, 2020

Introduction Multiple barriers have been described for reducing opioid prescribing by primary care providers. We describe a quality improvement report on the effects of a series of focused interventio...

Outcomes, Microbiology and Antimicrobial Usage in Pressure Ulcer-Related Pelvic Osteomyelitis: Messages for Clinical Practice.

May 28, 2020

: Pressure ulcer-related pelvic osteomyelitis is a relatively under-studied entity in the field of bone infection. We sought to add to the limited evidence base for managing this challenging syndrome....

Health-Related Quality of Life in Patients with Lung Cancer Applying Integrative Oncology Concepts in a Certified Cancer Centre.

May 28, 2020

Pretreatment health-related quality of life (HRQOL) is associated with survival outcome in lung cancer patients. There is a lack of systematic research on pretreatment HRQOL in lung cancer patients wh...

Efficacy of internet-delivered cognitive behavioural therapy following an acute coronary event: A randomized controlled trial.

May 28, 2020

Depression and anxiety are common among people who have experienced an acute coronary event (e.g., heart attack). Multidisciplinary cardiac rehabilitation programs often focus on reducing risk factors...

Mental Health Mobile Apps Don’t Meet Their Potential

May 15, 2020

Evidence and experience suggest that mental health-focused mobile apps hold the potential to overcome barriers to treatment in primary care. While safe and effective apps exist, evaluating and integra...

Trends in ED Admissions for Child Sexual Abuse

May 04, 2020

Physicians and nurses working in the ED are often the first to recognize sings of sexual abuse and identify children currently being abused. Although these emergency medicine professionals can serve m...

The Influence of Parental Marijuana Use on Children

Apr 30, 2020

Data suggest that the ascendancy of medicalization, legalization, and social acceptability of marijuana has resulted in an overall rise of past-year marijuana use from 11.0% (25.8 million) in 2002 to ...

Mental Disorders May Up Risk for Subsequent Medical Conditions

Apr 30, 2020

THURSDAY, April 30, 2020 (HealthDay News) -- The presence of a mental disorder is associated with an increased risk for many subsequent medical conditions, according to a study on a Danish population ...

Psoriasis Tied to Higher Alzheimer Disease Risk

Apr 30, 2020

THURSDAY, April 30, 2020 (HealthDay News) -- The incidence of Alzheimer disease (AD) is significantly higher in patients with psoriasis versus individuals without psoriasis, according to a Korean stud...

Young Athletes & Disordered Eating

Apr 29, 2020

Evidence suggests that disordered eating (DE) is a growing problem among adolescent athletes, with a negative impact on both physical and mental health. Additionally, DE can progress to eating disorde...

Pharmacological characterization of a novel potent, selective, and orally active orexin 2 receptor antagonist, SDM-878.

Apr 28, 2020

Recently, we identified a novel orexin 2 (OX ) receptor antagonist, SDM-878 (2-(3-(2-(1H-pyrazol-1-yl)nicotinoyl)-3,8-diazabicyclo[3.2.1]octan-8-yl)-3-methoxyisonicotinonitrile). The purpose of the pr...

Various Aspects of Tiagabine Effectiveness as Add-on Therapy in Patients with Refractory Epilepsy.

Apr 28, 2020

The aim of the present study was to investigate various aspects of tiagabine (TGB) effectiveness in Bulgarian patients with drug-resistant epilepsy. This open, prospective study recruited the patients...

Automated phase classification in cyclic alternating patterns in sleep stages using Wigner-Ville Distribution based features.

Apr 28, 2020

Sleep is one of the most important body mechanisms responsible for the proper functioning of human body. Cyclic alternating patterns (CAP) play an indispensable role in the analysis of sleep quality a...

Blackout of my nights: Contentless, timeless and selfless report from the night in patients with central hypersomnias.

Apr 28, 2020

At the extreme spectrum of consciousness during sleep, some patients with rare hypersomnias reported experiencing a specific night 'blackout' when sleeping, i.e., an absence of experiences or recall o...

Cognitive and Emotional Empathy in Individuals at Clinical High Risk of Psychosis.

Apr 28, 2020

Impairments of social cognition are considered core features of schizophrenia and are established predictors of social functioning. However, affective aspects of social cognition including empathy hav...

Region-specific effects of maternal separation on oxidative stress accumulation in parvalbumin neurons of male and female rats.

Apr 28, 2020

Early life adversity in humans is linked to cognitive deficits and increased risk of mental illnesses, including depression, bipolar disorder, and schizophrenia, with evidence for different vulnerabil...

Changes in the intracranial volume from early adulthood to the sixth decade of life: A longitudinal study.

Apr 28, 2020

Normal brain-aging occurs at all structural levels. Excessive pathophysiological changes in the brain, beyond the normal one, are implicated in the etiology of brain disorders such as severe forms of ...

A preliminary study to investigate resting state fMRI as a potential group differentiator for schizophrenia.

Apr 28, 2020

Schizophrenia (SZ) is found to be associated with dysconnectivity between the various regions of the brain. These aberrant connections in brain networks responsible for various mental processes in sch...

Lower cerebrospinal fluid CRH concentration in chronic schizophrenia with negative symptoms.

Apr 28, 2020

Some patients with schizophrenia have impaired hypothalamic-pituitary-adrenal axis function. However, there is a dearth of studies focusing on corticotropin-releasing hormone (CRH) levels in the brain...

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