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Psychiatry General

Individual differences in biological regulation: Predicting vulnerability to drug addiction, obesity, and other dysregulatory disorders.

Apr 28, 2020

Physiological regulation is so fundamental to survival that natural selection has greatly favored the evolution of robust regulatory systems that use both reactive and preemptive responses to mitigate...

Interventions to Support Family Caregivers in Pain Management: A Systematic Review.

Apr 28, 2020

Family caregivers encounter many challenges when managing pain for their loved ones. ​​There is a lack of clear recommendations on how to prepare caregivers in pain management.To evaluate existing...

Profile of cases discussed in innovative tele-ECHO mentoring program on addiction management.

Apr 28, 2020

NIMHANS ECHO (Extension for Community Healthcare Outcomes) model uses a video conferencing app to connect multiple community health care teams simultaneously with addiction treatment specialists and b...

Mitochondria in Alzheimer's disease and their potential role in Alzheimer's proteostasis.

Apr 28, 2020

Alzheimer's disease (AD) is a progressive brain disorder characterized by memory loss and the accumulation of two insoluble protein aggregates, tau neurofibrillary tangles and beta-amyloid plaques. Wi...

Subthalamic Deep Brain Stimulation modulates proprioceptive integration in Parkinson's Disease during a postural task.

Apr 28, 2020

Defective proprioceptive integration may play a role in the pathophysiology of motor symptoms in Parkinson's disease (PD). Dysfunction related to proprioceptively-evoked postural reactions in PD patie...

Do Lewy bodies contain alpha-synuclein fibrils? and Does it matter? A brief history and critical analysis of recent reports.

Apr 28, 2020

Several lines of evidence from neuropathological studies, human genetics, in vitro aggregation studies and cellular and animal models support the hypothesis that aSyn plays a central role in the forma...

Does perceived control mediate the relationship between stigma and well-being for individuals with Parkinson's disease?

Apr 28, 2020

Stigma is a known correlate of well-being for many neurological conditions. Perceived control is also an important variable in models of adaptation to living with a health condition. The purpose of th...

Radiofrequency Ablation of Prelemniscal Radiations for the Treatment of Non-Parkinsonian Tremor.

Apr 28, 2020

Previous reports proposed prelemniscal radiations (Raprl) as a target to treat motor symptoms of Parkinson's disease, and this was found particularly effective to control rest and postural tremor. How...

132 Treating Comorbid Childhood Bipolar Disorder and ADHD.

Apr 28, 2020

According to Nemeth et al. (2011), pediatric mania is difficult to distinguish from childhood hyperactivity. Both share 3 common symptoms: distractibility, motoric hyperactivity, and talkativeness (Bi...

156 The Broad Efficacy of Cariprazine Across Symptoms in Patients with Bipolar I Disorder: Post Hoc Analysis of Randomized, Placebo-Controlled Trials.

Apr 28, 2020

Patients with bipolar disorder experience a wide range of depressive and manic symptoms. Only 2 drugs are FDA-approved to treat episodes of both mania and depression in patients with bipolar disorder,...

162 Post-lithium Delirious Mania in Patients with Bipolar Disorder.

Apr 28, 2020

Delirious mania is a life-threatening condition, presenting with symptoms of acute delirium and psychotic mania as a complication of medical or psychiatric condition. It is not recognized as a diagnos...

155 Symptom Stability in de Novo and Rollover Patients with Bipolar I Disorder Receiving Aripiprazole Once-monthly in a 52-Week, Open-label Study.

Apr 28, 2020

Long-term maintenance treatment is essential in management of bipolar I disorder (BP-I) to achieve mood stability, prevent recurrence of mood episodes and improve functioning. Aripiprazole once-monthl...

The oropharyngeal microbiome is altered in individuals with schizophrenia and mania.

Apr 28, 2020

It is being increasingly recognized that human mucosal surfaces are not sterile but are colonized with microorganisms collectively known as the microbiome. The microbiome can alter brain functioning i...

[Experience of Practice-Based Psychiatrists and Neurologists During the COVID-19 Pandemic].

Apr 28, 2020

To date, to our knowledge there are no studies regarding attitudes and experiences of outpatient medical personnel during a pandemic. This study's aim was to evaluate the impact of the COVID-19 pandem...

Drug-Drug Interactions Between Lithium and Cardiovascular as Well as Anti-Inflammatory Drugs.

Apr 28, 2020

Lithium is the gold standard in treating bipolar affective disorders. As patients become increasingly older, drug-drug interactions leading to decreased excretion of lithium represent a key issue in l...

Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review of Clinical Trials and Case Reports.

Apr 28, 2020

Phenibut is a nootropic drug that exerts anxiolytic and antinociceptive effects by acting on the GABA receptor and the α-δ subunit of voltage-dependent calcium channels. An increased number of repor...

The FiCTION trial: Child oral health-related quality of life and dental anxiety across three treatment strategies for managing caries in young children.

Apr 28, 2020

The FiCTION trial compared co-primary outcomes (dental pain and/or infection) and secondary outcomes (child oral health-related quality of life [COHRQOL], child dental anxiety, cost-effectiveness, car...

MetagenoNets: comprehensive inference and meta-insights for microbial correlation networks.

Apr 28, 2020

Microbial association networks are frequently used for understanding and comparing community dynamics from microbiome datasets. Inferring microbial correlations for such networks and obtaining meaning...

libsbmljs-Enabling web-based SBML tools.

Apr 28, 2020

The SBML standard is used in a number of online repositories for storing systems biology models, yet there is currently no Web-capable JavaScript library that can read and write the SBML format. This ...

Benefits and Harms of Prescription Drugs and Supplements for Treatment of Clinical Alzheimer-Type Dementia: A Systematic Review and Meta-analysis.

Apr 28, 2020

Effects of drug treatment of clinical Alzheimer-type dementia (CATD) are uncertain.To summarize evidence on the effects of prescription drugs and supplements for CATD treatment.Electronic bibliographi...

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