Advertisement

Psychiatry General

20-Year Trends in the Pharmacologic Treatment of Bipolar Disorder by Psychiatrists in Outpatient Care Settings.

Apr 24, 2020

Pharmacological options for treating bipolar disorder have increased over the past 20 years, with several second-generation antipsychotics receiving regulatory approval in the 1990s. The authors descr...

Pseudobulbar Affect Presenting as Hypomania.

Apr 24, 2020

Pseudobulbar affect (PBA) is a behavioral syndrome associated with various neurological conditions that typically manifests as uncontrollable laughing or crying. PBA can significantly impact the quali...

More Purpose in Life and Less Novelty Seeking Predict Improvements in Self-Compassion During a Mindfulness-Based Intervention: The EXMIND Study.

Apr 24, 2020

Recently, a 4-week mindfulness-based intervention followed by a 4-week existential approach was found to be as effective for increasing self-compassion as an 8-week mindfulness-based intervention. The...

Cerebral Impaludation - An Ignoble Procedure between Two Nobel Prizes: Frontal Lobe Lesions before the Introduction of Leucotomy.

Apr 24, 2020

During the 20th century, only two persons have been awarded the Nobel Prize for psychiatric discoveries, Julius Wagner-Jauregg in 1927 for the introduction of malaria inoculation in dementia paralytic...

Effects of an Individualized Comprehensive Rehabilitation Program on impaired postural control in women with chronic pelvic pain: a randomized controlled trial.

Apr 24, 2020

To assess the effectiveness of an Individualized Comprehensive Rehabilitation Program (ICPR) on impaired postural control, pain, self-perceived health status and functionality in women with CPP.A rand...

Enhanced conditioning of adverse memories in the mouse modified swim test is associated with neuroinflammatory changes - effects that are susceptible to antidepressants.

Apr 24, 2020

Deficient learning and memory are well-established pathophysiologic features of depression, however, mechanisms of the enhanced learning of aversive experiences associated with this disorder are poorl...

Neurobehavioral Changes Arising from Early Life Dopamine Signaling Perturbations.

Apr 24, 2020

Dopamine (DA) signaling is critical to the modulation of multiple brain functions including locomotion, reinforcement, attention and cognition. The literature provides strong evidence that altered DA ...

Early postnatal l-Dopa treatment causes behavioral alterations in female vs. male young adult Swiss mice.

Apr 24, 2020

Dopaminergic signaling and neurodevelopment alterations are associated with several neuropsychiatric disorders. Knockout mice for dopamine transporters (DAT) as well as site-specific knockout mice lac...

Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey.

Apr 24, 2020

China has been severely affected by Coronavirus Disease 2019(COVID-19) since December, 2019. We aimed to assess the mental health burden of Chinese public during the outbreak, and to explore the poten...

Sequence matters: patterns in task-based clinical reasoning.

Apr 24, 2020

Background The cognitive pathways that lead to an accurate diagnosis and efficient management plan can touch on various clinical reasoning tasks (1). These tasks can be employed at any point during th...

Neuromodulation in primary headaches: current evidence and integration into clinical practice.

Apr 24, 2020

Neuromodulatory approaches add to our armamentarium of therapeutic tools for the treatment of primary headaches. This review provides a comprehensive overview of current controlled studies on the diff...

Targeting mitochondrial and cytosolic substrates of TRIT1 isopentenyltransferase: Specificity determinants and tRNA-i6A37 profiles.

Apr 24, 2020

The tRNA isopentenyltransferases (IPTases), which add an isopentenyl group to N6 of A37 (i6A37) of certain tRNAs, are among a minority of enzymes that modify cytosolic and mitochondrial tRNAs. Pathoge...

Ancient genomes reveal the evolutionary history and origin of cashmere producing goats in China.

Apr 24, 2020

Goats are one of the most widespread farmed animals across the world; however, their migration route to East Asia and local evolutionary history remain poorly understood. Here, we sequenced 27 ancient...

Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents.

Apr 24, 2020

Malaria is a parasitic disease endemic to tropical and subtropical regions responsible for hundreds of millions of clinical cases and hundreds of thousands of deaths yearly. Its agent, the sp., has a...

Breast surgery and peripheral blocks. Is it worth it?

Apr 24, 2020

The objective of this review is to identify the potential of peripheral nerve blocks established over the last years for perioperative pain management in breast surgery. These new blocks will be discu...

Liposomal Bupivacaine Is Both Safe and Effective in Controlling Postoperative Pain After Spinal Surgery in Children: A Controlled Cohort Study.

Apr 24, 2020

Retrospective comparative cohort study.To evaluate: (1) pain relief efficacy; (2) opioid consumption; (3) length of stay (LOS); (4) discharge disposition (DD); and (5) safety and adverse effects of li...

Dedicated emergency department physical therapy is associated with reduced imaging, opioid administration, and length of stay: A prospective observational study.

Apr 24, 2020

Emergency department based Physical Therapy (ED-PT) has been practiced globally in various forms for over 20 years and is an emerging resource in the US. While there is a growing body of evidence sugg...

Sex Differences in Early Cognitive Development After Prenatal Exposure to Opioids.

Apr 24, 2020

Prenatal opioid exposure has been linked with impaired cognitive development, with boys potentially at elevated risk. In the present study, we examined cognitive and language development of children p...

Characteristics, symptom management and outcomes of 101 patients with COVID-19 referred for hospital palliative care.

Apr 24, 2020

Hospital palliative care is an essential part of the COVID-19 response but data are lacking. We identified symptom burden, management, response to treatment, and outcomes for a case series of 101 in-p...

Utility, Appropriateness, and Content of Electronic Consultations Across Medical Subspecialties: A Cohort Study.

Apr 14, 2020

Electronic consultations (e-consults) can facilitate patient access to specialists, minimize travel, and reduce unnecessary in-person visits. However, metrics to enable study of e-consults and their e...

SUBSPECIALTIES

Advertisement