Apr 12, 2020

It remains unclear whether specific clinical factors contribute to heterogeneity in the timing of the onset of nonfatal suicidal behavior. This knowledge could have important implications for suicide ...

Apr 12, 2020

Lithium is the mainstay for the maintenance treatment of mood disorders (MD), but its efficacy needs to be weighed against its side effects profile. Here, we assessed retrospectively the clinical resp...

Apr 12, 2020

To reanalyze Aristotle's classic lecture, "On melancholy," with current clinical interpretations METHOD: The full lecture is described and interpreted in a new translation.Aristotle's lecture has been...

Apr 12, 2020

The ability of environmental pollutants to alter the epigenome with resultant development of behavioral alterations has received more attention in recent years. These alterations can be transmitted an...

Apr 12, 2020

Anxiety disorders are often preceded by interpersonal stress; however, most individuals who experience stress do not develop anxiety, making it difficult to predict who is most susceptible to stress. ...

Apr 12, 2020

Few studies have attempted to identify how distinct dimensions of maternal prenatal affective symptoms relate to offspring psychopathology. We defined latent dimensions of women's prenatal affective s...

Apr 12, 2020

Air pollution is associated with adverse impacts on the brain, including cognitive decline and increased incidence of dementia, depression and anxiety; however, underlying mechanisms remain unclear. W...

Apr 12, 2020

Early onset group B streptococcal (EOGBS) disease is an important cause of neonatal morbidity and mortality. EOGBS preventive strategies aim to reduce the risk of neonatal complications. Two new strat...

Apr 12, 2020

Four-dimensional (4D) printing can add active and responsive functions to three-dimensional (3D) printed objects in response to various external stimuli. Light, among others, has a unique advantage of...

Apr 12, 2020

Neuropharmacological and human clinical studies have suggested that the brain dopaminergic system is substantively involved in normal and pathological phenotypes of attention. Dopamine transporter gen...

Apr 12, 2020

Peripheral Myelin Protein 2 (PMP2) is a small protein located on the cytoplasmic side of compact myelin, involved in the lipids transport and in the myelination process. In the last years few families...

Apr 12, 2020

Nodal status represents probably the most important determinant of gastric cancer prognosis. The purpose of the present study was to assess the impact of the primary tumor's T stage on lymph node harv...

Apr 12, 2020

Oxford Nanopore technologies (ONT) add miniaturization and real-time to high-throughput sequencing. All available software for ONT data analytics run on cloud/clusters or personal computers. Instead, ...

Apr 12, 2020

Neuropathic pain remains a significant unmet medical need. Several recommendations have recently been proposed concerning pharmacotherapy, neurostimulation techniques and interventional management, bu...

Apr 12, 2020

High-risk opioid prescribing practices in workers' compensation (WC) settings are associated with excess opioid-related morbidity, longer work disability and higher costs. This study characterises the...

Apr 12, 2020

There is increasing interest in the bioactivity of peptides carrying out antiproliferative, antihypertensive, antimicrobial, antioxidant, anticholesterolemic, opioid, and antidiabetic activities. The ...

Apr 12, 2020

Elements of the physical environment have been shown to influence health behaviors including drug use and overdose mortality. Throughout the opioid epidemic in the United States, rural regions have be...

Apr 12, 2020

This paper includes the voices of people who are members of a peer-led drug user group (SNAP) in Canada who are receiving heroin-assisted treatment (HAT) outside of a clinical trial. Drawing from crit...

Apr 08, 2020

It's jarring every time. The sudden crash in patients with COVID-19 All over the world, seemingly mild cases of COVID-19 rapidly morph into severe cases that involve the lower lungs. This may b...

Apr 03, 2020

We analyzed data from a practice-based randomized controlled trial within 20 primary care practices located in greater New York City, Philadelphia, and Pittsburgh to determine whether persistent or wo...