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Psychiatry General

Neurodegenerative diseases and Withania somnifera (L.): An update.

Apr 03, 2020

Withania somnifera(L.)Dunal, also known as Ashwaghanda" in Sanskrit and as"Indian Winter Cherry in english"is an important medicinal herb. It is widely used in Indian systems of medicine as an adaptog...

The relationship between sleep duration and mood in adolescents: A systematic review and meta-analysis.

Apr 03, 2020

Insufficient sleep has been argued to result in deleterious changes to mood in adolescents and offers promise as a modifiable risk factor. A systematic review of the literature regarding sleep duratio...

Ketamine and nitrous oxide: The evolution of NMDA receptor antagonists as antidepressant agents.

Apr 03, 2020

N-methyl-d-aspartate receptor (NMDAR) antagonists, including ketamine and nitrous oxide, are currently intensely studied as rapid-acting antidepressant agents. Interestingly, both of these compounds a...

Pharmacist Medication Management of Adults with Attention Deficit: An Alternative Clinical Structure.

Apr 03, 2020

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric conditions in youth. This disorder can persist into adulthood, with an estimated prevalence of 4.4% to 5.2% in the...

Guava leaves extract ameliorates STZ induced diabetes mellitus via activation of PI3K/AKT signaling in skeletal muscle of rats.

Apr 03, 2020

Blood glucose homeostasis and insulin signaling pathway regulation take a vital role in the management of diabetes mellitus. Our present was designed to explore the mechanism of the blood homeostasis,...

Dupilumab: A Review in Chronic Rhinosinusitis with Nasal Polyps.

Apr 03, 2020

Dupilumab (Dupixent) is a fully human IgG4 monoclonal antibody against the interleukin (IL)-4 receptor α (IL-4Rα) subunit, which is shared by the type I IL-4 and the type II IL-4/IL-13 receptor com...

Genetic deletion of microRNA biogenesis in muscle cells reveals a hierarchical non-clustered network that controls focal adhesion signaling during muscle regeneration.

Apr 03, 2020

Decreased muscle mass is a major contributor to age-related morbidity, and strategies to improve muscle regeneration during ageing are urgently needed. Our aim was to identify the subset of relevant m...

Cost savings in colonoscopy with artificial intelligence-aided polyp diagnosis: an add-on analysis of a clinical trial (with video).

Apr 03, 2020

Artificial intelligence (AI) is being implemented into colonoscopy practice, but no study has investigated whether AI is cost-saving. We quantified the cost reduction from using AI as an aid in the op...

[Excitatory and aversive behaviors - electrophysiological observation of anterior cingulate cortex (ACC) in rats].

Apr 03, 2020

Increasing activities in anterior cingulate cortex (ACC) can enhance the aversion reactions associated with noxious stimuli. It has been known that opioid receptors activation can trigger endogenous a...

Nonfatal Drug Overdoses Treated in Emergency Departments - United States, 2016-2017.

Apr 03, 2020

In 2017, drug overdoses caused 70,237 deaths in the United States, a 9.6% rate increase from 2016 (1). Monitoring nonfatal drug overdoses treated in emergency departments (EDs) is also important to in...

Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain.

Apr 03, 2020

Effective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic. Persistent postsurgical pain (PPP) has an inc...

Use of new psychoactive substances to mimic prescription drugs: the trend in France.

Apr 03, 2020

Among the expanding world of New Psychoactive Substances (NPS), Designer Medicines (DM) are designed to mimic psychoactive drugs and might lead to adverse events of various severity. The DM category i...

Antibody avidity-based approach to estimate population-level incidence of hepatitis C.

Apr 03, 2020

Accurate hepatitis C virus (HCV) incidence estimates are critical for monitoring progress towards HCV elimination goals, including an 80% reduction in HCV incidence by 2030. Moreover, incidence estima...

Many Legal Marijuana Products Too Strong for Treating Pain

Apr 03, 2020

FRIDAY, April 3, 2020 (HealthDay News) -- Legally dispensed marijuana products have stronger concentrations of tetrahydrocannabinol (THC) and cannabidiol (CBD) than needed for chronic pain relief, acc...

Late-Life Depression Severity Varies by Race, Ethnicity

Mar 27, 2020

FRIDAY, March 27, 2020 (HealthDay News) -- Significant racial and ethnic differences have been identified in late-life depression (LLD) severity, symptom burden, and depression care, according to a st...

Updated ADHD Clinical Practice Guidelines

Mar 26, 2020

 “It has been 8 years since The American Academy of Pediatrics (AAP) updated the Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disord...

FDA Warns of Defective EpiPen Dangers

Mar 25, 2020

WEDNESDAY, March 25, 2020 (HealthDay News) -- Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food...

Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments.

Mar 24, 2020

Withania somnifera popularly known as Aswagandha or Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian traditional medicine. Besides, finding place root of the plant as ...

Association of sleep among 30 antidepressants: a population-wide adverse drug reaction study, 2004-2019.

Mar 24, 2020

Sleep is one of the most essential processes required to maintain a healthy human life, and patients experiencing psychiatric illness often experience an inability to sleep. The aim of this study is t...

Quality of life of patients more than 1 year after surgery for thyroid cancer.

Mar 24, 2020

Patients with thyroid cancer are often assumed to have no quality of life (QOL) impairments after treatment because of thyroid cancer's good prognosis. However, the QOL implications of surgical compli...

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