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Psychiatry General

Updated ADHD Clinical Practice Guidelines

Mar 26, 2020

 “It has been 8 years since The American Academy of Pediatrics (AAP) updated the Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disord...

FDA Warns of Defective EpiPen Dangers

Mar 25, 2020

WEDNESDAY, March 25, 2020 (HealthDay News) -- Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food...

Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments.

Mar 24, 2020

Withania somnifera popularly known as Aswagandha or Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian traditional medicine. Besides, finding place root of the plant as ...

Association of sleep among 30 antidepressants: a population-wide adverse drug reaction study, 2004-2019.

Mar 24, 2020

Sleep is one of the most essential processes required to maintain a healthy human life, and patients experiencing psychiatric illness often experience an inability to sleep. The aim of this study is t...

Quality of life of patients more than 1 year after surgery for thyroid cancer.

Mar 24, 2020

Patients with thyroid cancer are often assumed to have no quality of life (QOL) impairments after treatment because of thyroid cancer's good prognosis. However, the QOL implications of surgical compli...

Selecting a pharmacotherapy regimen for patients with chronic insomnia.

Mar 24, 2020

: Chronic insomnia, whether it is primary or in combination with another medical or psychiatric disorder, is a prevalent condition associated with significant morbidity, reduced productivity, increase...

Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019.

Mar 24, 2020

Health care workers exposed to coronavirus disease 2019 (COVID-19) could be psychologically stressed.To assess the magnitude of mental health outcomes and associated factors among health care workers ...

BMI-NECK: A simple assessment of risk of obstructive sleep apnea in schizophrenia.

Mar 24, 2020

A high risk of obstructive sleep apnea (OSA) has been reported in patients with schizophrenia. However, existing screening questionnaires for OSA haven't been validated in this population and the impa...

Occupation-focused intervention for in-patient mental health settings: Pilot study of effectiveness.

Mar 24, 2020

Participation in meaningful occupation is associated with recovery in serious mental illnesses, however, few evidence-based, occupation-focused interventions for hospital settings exist. This study in...

Magnetic resonance spectroscopy studies in subjects with high risk for psychosis: A meta-analysis and review.

Mar 24, 2020

Even though anomalies on brain metabolites have been found in schizophrenia, researches about subjects with high risk (HR) show heterogeneous results. Thus, this meta-analysis aims to characterize the...

An operant social self-administration and choice model in rats.

Mar 24, 2020

It is difficult to translate results from animal research on addiction to an understanding of the behavior of human drug users. Despite decades of basic research on neurobiological mechanisms of drug ...

The prevalence of confirmed childhood trauma and its' impact on psychotic-like experiences in a sample of Chinese adolescents.

Mar 24, 2020

Adolescents with childhood trauma may be associated with psychotic-like experiences (PLEs) and is at high risk for later development of psychoses. Exploring early age risk factors for childhood trauma...

Improving social functioning in community-dwelling patients with schizophrenia: a randomized controlled computer cognitive remediation therapy trial with six months follow-up.

Mar 24, 2020

Computerized cognitive remediation therapy (CCRT) has been found to generally improve cognition among patients with schizophrenia, but its effect on functioning has not been extensively studied. This ...

Thioredoxin-1 blocks methamphetamine-induced injury in brain through inhibiting endoplasmic reticulum and mitochondria-mediated apoptosis in mice.

Mar 24, 2020

Methamphetamine (METH) has been reported to induce endoplasmic reticulum (ER) stress and neuronal apoptosis in the central nervous system (CNS) during the development of addiction. Thioredoxin-1 (Trx-...

Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress.

Mar 24, 2020

Depression is a common disease that afflicts one in 6 people. Numerous hypotheses have been raised in the past decades, but the exact mechanism for depression onset remains obscure. Recently, the neur...

Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer's disease in patients with rheumatoid arthritis and psoriasis.

Mar 24, 2020

This large, retrospective case-control study of electronic health records from 56 million unique adult patients examined whether or not treatment with a Tumor Necrosis Factor (TNF) blocking agent is a...

Basal forebrain volume reliably predicts the cortical spread of Alzheimer's degeneration.

Mar 24, 2020

Alzheimer's disease neurodegeneration is thought to spread across anatomically and functionally connected brain regions. However, the precise sequence of spread remains ambiguous. The prevailing model...

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease.

Mar 24, 2020

We performed post-mortem studies on two patients with advanced Parkinson's disease 8 and10 years following AAV2-neurturin (CERE120) gene therapy, the longest post-mortem trophic factor gene therapy ca...

Synchronous measuring of triptolide changes in rat brain and blood and its application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats.

Mar 24, 2020

Triptolide, a major active ingredient of Tripterygium wilfordii Hook F, provides anti-inflammatory and neuroprotective activities. In this study, a microwave-assisted stable isotope labeling derivatiz...

Higher vitamin B12 level at Parkinson's disease diagnosis is associated with lower risk of future dementia.

Mar 24, 2020

To determine whether vitamin B12 level at Parkinson's disease (PD) diagnosis predicts time to develop dementia.We utilized a population-based cohort of Parkinsonism patients to examine the relationshi...

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