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Psychiatry General

Alzheimer's Disease and Vascular Aging: JACC Focus Seminar.

Mar 05, 2020

Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in the brain. However, ...

The Alzheimer's Disease Amyloid-Beta Hypothesis in Cardiovascular Aging and Disease: JACC Focus Seminar.

Mar 05, 2020

Aging-related cellular and molecular processes including low-grade inflammation are major players in the pathogenesis of cardiovascular disease (CVD) and Alzheimer's disease (AD). Epidemiological stud...

Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders.

Mar 05, 2020

The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-onset dementia. The diagnosis of bvFTD remains challenging because of the limited accuracy of neuroimaging in th...

Evaluating naloxegol for the treatment of opioid-induced constipation.

Mar 05, 2020

: Due to the increased use of opioids for pain and their abuse globally, the rate of restrictive side effects is elevating. Opioid-induced constipation (OIC) is probably the most widespread, underdiag...

To What Extent Does Clinically Assisted Nutrition and Hydration Have a Role in the Care of Dying People?

Mar 05, 2020

The question over whether to administer clinically assisted nutrition and hydration (CANH) to a dying patient is controversial, with much debate concerning this sensitive issue. The administration of ...

Opioid growth factor and its derivatives as potential non-toxic multifunctional anticancer and analgesic compounds.

Mar 05, 2020

Despite significant research progress on the pathogenesis, molecular biology, diagnosis, treatment, and prevention of cancer its morbidity and mortality is still high around the world. The emerging re...

Promoting Reproducible Research for Characterizing Nonmedical Use of Medications Through Data Annotation: Description of a Twitter Corpus and Guidelines.

Mar 05, 2020

Social media data are being increasingly used for population-level health research because it provides near real-time access to large volumes of consumer-generated data. Recently, a number of studies ...

Opioid Naive Surgeons and Opioid-Tolerant Patients: Can Education Alter Prescribing Patterns to Total Knee Arthroplasty Patients?

Mar 05, 2020

Patterns of opioid overprescribing following arthroplasty likely developed given that poor pain control can diminish patient satisfaction, delay disposition, and lead to complications. Recently, inter...

FDA Bans Electrical Shock Devices Used on the Mentally Disabled

Mar 04, 2020

WEDNESDAY, March 4, 2020 (HealthDay News) -- Electrical shock devices (ESDs) used to reduce aggression and self-harm in patients with autism and other developmental disabilities will be banned, the U....

Considerable Increase Seen in List, Net Prices of Branded Drugs

Mar 04, 2020

WEDNESDAY, March 4, 2020 (HealthDay News) -- From 2007 to 2018, there were substantial increases in list and net prices of branded drugs in the United States, according to a study published in the Mar...

Neuroimaging of Narcolepsy and Primary Hypersomnias.

Mar 02, 2020

Advances in neuroimaging open up the possibility for new powerful tools to be developed that potentially can be applied to clinical populations to improve the diagnosis of neurological disorders, incl...

Emotions relating to romantic love-further disruptors of adolescent sleep.

Mar 02, 2020

Early-stage romantic involvement may resemble hypomania in its manifestation on behavioral, physiological, and psychological levels. Previous research suggests that self-reported sleep duration may di...

Insomnia, Hypnotic Use, and Road Collisions: A Population-Based, 5-Year Cohort Study.

Mar 02, 2020

The study objectives were to examined accidental risks associated with insomnia or hypnotic medications, and how these risk factors interact with sex and age.A population-based sample of 3413 adults (...

Digital Cognitive Behavioral Therapy for Insomnia in Women With Chronic Migraines.

Mar 02, 2020

Insomnia commonly co-occurs with chronic migraines (CM). Non-pharmacological treatments for insomnia in CM patients remain understudied. This is a proof-of-concept study, which aims to evaluate the fe...

Long-term benefits of digital cognitive behavioural therapy for insomnia: Follow-up report from a randomized clinical trial.

Mar 02, 2020

Digital cognitive behavioural therapy (dCBT) is an effective treatment for chronic insomnia and also improves well-being and quality of life (QoL). We assessed whether these benefits are sustained and...

Exposure to air pollution during childhood and risk of developing schizophrenia: a national cohort study.

Mar 02, 2020

Ambient air pollution affects neurological function, but its association with schizophrenia risk is unclear. We investigated exposure to nitrogen oxides (NO) as a whole and nitrogen dioxide (NO) speci...

The dosage-dependent effects of cevimeline in preventing olanzapine-induced metabolic side-effects in female rats.

Mar 02, 2020

Olanzapine has been used for the treatment of schizophrenia and other mental disorders. However, it is associated with serious weight gain and other metabolic side-effects. The antagonistic affinity o...

Real-time fMRI feedback impacts brain activation, results in auditory hallucinations reduction: Part 1: Superior temporal gyrus -Preliminary evidence.

Mar 02, 2020

Auditory hallucinations (AH) are one of the core symptoms of schizophrenia (SZ) and constitute a significant source of suffering and disability. One third of SZ patients experience pharmacology-resist...

Substance use disorders before, at and after first episode psychosis hospitalizations in a young national Swedish cohort.

Mar 02, 2020

Comorbidity between Substance use disorders (SUD) and psychotic disorders is common but the temporal relation of the first episodes of SUD and psychosis and how it affects the disorders has not been e...

Removal of sulfadiazine and ciprofloxacin by clays and manganese oxides: Coupled sorption-oxidation kinetic model.

Mar 02, 2020

Sorption onto clays (montmorillonite and kaolinite), oxidation and sorption by manganese oxides (synthesized MnO and natural MnO), and coupled sorption-oxidation experiments were conducted for the rem...

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