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Psychiatry General

Exposure to air pollution during childhood and risk of developing schizophrenia: a national cohort study.

Mar 02, 2020

Ambient air pollution affects neurological function, but its association with schizophrenia risk is unclear. We investigated exposure to nitrogen oxides (NO) as a whole and nitrogen dioxide (NO) speci...

The dosage-dependent effects of cevimeline in preventing olanzapine-induced metabolic side-effects in female rats.

Mar 02, 2020

Olanzapine has been used for the treatment of schizophrenia and other mental disorders. However, it is associated with serious weight gain and other metabolic side-effects. The antagonistic affinity o...

Real-time fMRI feedback impacts brain activation, results in auditory hallucinations reduction: Part 1: Superior temporal gyrus -Preliminary evidence.

Mar 02, 2020

Auditory hallucinations (AH) are one of the core symptoms of schizophrenia (SZ) and constitute a significant source of suffering and disability. One third of SZ patients experience pharmacology-resist...

Substance use disorders before, at and after first episode psychosis hospitalizations in a young national Swedish cohort.

Mar 02, 2020

Comorbidity between Substance use disorders (SUD) and psychotic disorders is common but the temporal relation of the first episodes of SUD and psychosis and how it affects the disorders has not been e...

Removal of sulfadiazine and ciprofloxacin by clays and manganese oxides: Coupled sorption-oxidation kinetic model.

Mar 02, 2020

Sorption onto clays (montmorillonite and kaolinite), oxidation and sorption by manganese oxides (synthesized MnO and natural MnO), and coupled sorption-oxidation experiments were conducted for the rem...

Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder.

Mar 02, 2020

The Hypothalamus-Pituitary-Gonadal (HPG)-axis, and testosterone in particular, play an important role in social motivational behavior. Socially avoidant behavior, characteristic of social anxiety diso...

Ethanol metabolism: The good, the bad, and the ugly.

Mar 02, 2020

Throughout the world, ethanol is both an important commercial commodity and a source of major medical and social problems. Ethanol readily passes through biological membranes and distributes throughou...

Kidney Disease-Specific Scores and Health Utility of Continuous Ambulatory Peritoneal Dialysis Patients, Automated Peritoneal Dialysis Patients, and Caregivers.

Mar 02, 2020

This study aimed to compare the EuroQol 5-dimension 5-level questionnaire (EQ-5D-5L), the visual analogue scale (VAS), and the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36) score...

EGFR signaling causes morphine tolerance and mechanical sensitization in rats.

Mar 02, 2020

The safety and efficacy of opioids are compromised as analgesic tolerance develops. Opioids are also ineffective against neuropathic pain. Recent reports have suggested that inhibitors of the epiderma...

The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor.

Mar 02, 2020

Opioid agonist activation at the mu opioid receptor (MOR) can lead to a wide variety of physiological responses. Many opioid agonists share the ability to selectively and preferentially activate speci...

Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expression.

Mar 02, 2020

Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the development of tolerance and of opioid-induced hyperalgesia, both limiting the analgesic use of morphine. We e...

Opioid prescriptions in emergency departments: Findings from the 2016 National Hospital Ambulatory Medical Care Survey.

Mar 02, 2020

In the past decade, there has been a rising trend in the emergency department (ED) visits in the US and these visits carry a significant burden of prescription opioids. This study utilized the latest ...

Comprehensive Analysis of the Effects of Ketorolac Administration After Pancreaticoduodenectomy.

Mar 02, 2020

Outcome improvement is a major goal of pancreatic surgery. Such efforts include decreasing perioperative narcotic use to optimize care and reduce potential contributions to the opioid crisis. Ketorola...

New insights on the structure of alpha-synuclein fibrils using cryo-electron microscopy.

Mar 02, 2020

Fibrils of alpha-synuclein are significant components of cellular inclusions associated with several neuropathological disorders including Parkinson's disease, multiple system atrophy and dementia wit...

Priming older adults and people with mild to moderate Alzheimer's disease problem-solving with false memories.

Mar 02, 2020

In two experiments we investigated whether older adult controls (OACs) and people with mild and moderate Alzheimer's disease (AD) benefit from false memory priming effects in subsequent problem-solvin...

Diagnostic potential of automated tractography in progressive supranuclear palsy variants.

Mar 02, 2020

Microstructural white matter integrity captured by diffusion-tensor imaging (DTI) is significantly more affected in progressive supranuclear palsy-Richardson's syndrome (PSP-RS) compared to PSP-parkin...

Neocortical morphometry in Huntington's disease: Indication of the coexistence of abnormal neurodevelopmental and neurodegenerative processes.

Mar 02, 2020

Huntington's disease (HD) is an inherited, autosomal dominant disorder that is characteristically thought of as a degenerative disorder. Despite cellular and molecular grounds suggesting HD could also...

The Heart Failure with Preserved Ejection Fraction Conundrum-Redefining the Problem and Finding Common Ground?

Mar 02, 2020

Heart failure with preserved ejection fraction (HFpEF) or diastolic heart failure (DHF) makes up more than half of all congestive heart failure presentations (CHF). With an ageing population, the case...

Broader phenotypic traits and widespread brain hypometabolism in spinocerebellar ataxia 27.

Mar 02, 2020

The goal of this study was to characterize a Swedish family with members affected by spinocerebellar ataxia 27 (SCA27), a rare autosomal dominant disease caused by mutations in fibroblast growth facto...

Associations between ADHD and emotional problems from childhood to young adulthood: a longitudinal genetically sensitive study.

Mar 02, 2020

Attention deficit/hyperactivity disorder (ADHD) is associated with emotional problems, and their co-occurrence often leads to worse outcomes. We investigated the developmental associations between ADH...

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