Feb 25, 2020

Benzodiazepines (BDZ) and z-drugs belong to the most frequently prescribed medicines worldwide used for anxiety, epilepsy and sleeping disorders. Due to their pharmacology, they have a high potential ...

Feb 25, 2020

Non-motor symptoms (NMS) are common in Parkinson's disease (PD), but their relationships to nigrostriatal degeneration remain largely unexplored.We evaluated 18 NMS scores covering 5 major domains in ...

Feb 25, 2020

The clinical features and implications of dizziness in patients with Parkinson's disease (PD) remain little known. This study aimed to investigate the clinical characteristics of dizziness, and the as...

Feb 25, 2020

There are limited data on the effect of donor body mass index (BMI) on peripheral blood stem cell (PBSC) mobilization response to granulocyte colony-stimulating factor (G-CSF), especially in unrelated...

Feb 25, 2020

Children with attention deficit hyperactivity disorder (ADHD) and nocturnal enuresis (NE) have similar symptoms e.g. inattention and dysfunction of working memory. We investigate disorder-specific abn...

Feb 25, 2020

AMP-activated protein kinase (AMPK) is an important energy sensor located in cells throughout the human body. From the periphery, AMPK is known to be a metabolic master switch controlling the use of e...

Feb 25, 2020

Sustainable development demands radical rethinking of national economies, now mainly based on a linear approach. The transition to a circular one requires crucial innovations and disruptive changes an...

Feb 25, 2020

Medium density fiberboard (MDF) wastes were converted into an efficient char able to uptake Food Red 17 dye (FR17) from colored effluents. The yield of the pyrolysis process, in terms of char, was 29%...

Feb 25, 2020

Lidocaine infusion for pain control has been used for years. While some centers transition from continuous infusion lidocaine to oral mexiletine, there are no published studies to guide this conversio...

Feb 25, 2020

Studies have shown barriers to appropriate narcotic use in the Middle East have negatively impacted patient outcomes. This study aimed to explore health professionals' perspectives regarding opioid us...

Feb 25, 2020

Substance use is common in women of reproductive age, but limited data exist on the dental health of their children, including risk of caries. We conducted a longitudinal cohort study of 790,758 infan...

Feb 25, 2020

Morphine and its derivatives play inevitably important role in the μ-opioid receptor (MOR) targeted antinociception. A structure-activity relationship study is presented for novel and known orvinol a...

Feb 25, 2020

DCC netrin 1 receptor (DCC) affects the structure and function of the dopamine circuitry, which in turn affects the susceptibility to developing addiction. In a previous study, we found that single nu...

Feb 21, 2020

Research indicates that adults with asthma as well as depression, anxiety, or both demonstrate higher asthma-related healthcare use, including emergency department (ED) visits. Naomi S. Bardach, MD, M...

Feb 19, 2020

WEDNESDAY, Feb. 19, 2020 (HealthDay News) -- Prescription medications, especially analog insulin, can be found on Craigslist, according to a research letter published online Feb. 17 in JAMA Internal M...

Feb 18, 2020

Sleep state misperception is common in various sleep disorders, especially in chronic insomnia with a prevalence ranging between 9-50%. Most prior studies used nocturnal polysomnography (PSG) for the ...

Feb 18, 2020

Clinical factors associated with daytime sleepiness and insomnia in persons with epilepsy (PWE) were examined in this cross-sectional study of 126 participants (men, 50.8%). Excessive daytime sleepine...

Feb 18, 2020

This double-blind placebo-controlled, fixed/flexible-dose phase 2 trial assessed the efficacy, safety, and tolerability of cariprazine vs. placebo for depressive episodes associated with bipolar I or ...

Feb 18, 2020

Dust and fumes are complex mixtures of airborne gases and fine particles present in all environments inhabited by people. This study investigated the relationship between occupational dust exposure le...

Feb 18, 2020

Addiction is associated with health-related and social risks. The interministerial harmonized Lower Saxon concept on drug prevention was most recently revised in 2008 and is predominantly implemented ...