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Psychiatry General

Associations between Neighborhood-Level Factors and Opioid-Related Mortality: A Multilevel Analysis using Death Certificate Data.

Feb 17, 2020

To identify associations between opioid-related mortality and neighborhood-level risk factors.Cross-sectional study.Massachusetts, USA.Using 2011-2014 Massachusetts death certificate data, we identifi...

Molecular heterogeneity in breast carcinoma cells with increased invasive capacities.

Feb 17, 2020

Background Metastatic progression of breast cancer is still a challenge in clinical oncology. Therefore, an elucidation how carcinoma cells belonging to different breast cancer subtypes realize their ...

U.S. Life Expectancy to Reach 85 by 2060

Feb 14, 2020

FRIDAY, Feb. 14, 2020 (HealthDay News) -- Nearly a quarter of all U.S. residents will be older than 65 by 2060, and life expectancy will reach an all-time high of 85 by that year, according to the U.S...

Sleep time and sleep-related symptoms across two generations - results of the community-based RHINE and RHINESSA studies.

Feb 13, 2020

To analyze the association between sleep-related symptoms and sleep length in parents and their children in relation to other risk factors in both generations.The participants were parents (n = 5,85...

Adolescent Sjogren's syndrome presenting as psychosis: a case series.

Feb 13, 2020

Neurological involvement has been reported in up to 80% of adults with Primary Sjogren's syndrome (pSS) with psychiatric abnormalities including anxiety, depression, and cognitive dysfunction being co...

Resting-state brain network topological properties and the correlation with neuropsychological assessment in adolescent narcolepsy.

Feb 13, 2020

To evaluate functional connectivity and topological properties of brain networks, and to investigate the association between brain topological properties and neuropsychiatric behaviors in adolescent n...

Hypnotic prescription by GPs is associated with their personal drug consumption but not by their insomnia status.

Feb 13, 2020

French general practitioners (GPs) are known to widely prescribe medications to treat insomnia despite their negative effects. GPs' easy access to self-medication may affect their mental representatio...

An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.

Feb 13, 2020

Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider a broader clinical spectrum, disentangle illne...

Psychotic Experiences Are Associated With Paternal Age But Not With Delayed Fatherhood in a Large, Multinational, Community Sample.

Feb 13, 2020

Advanced paternal age has been consistently associated with an increased risk of schizophrenia. It is less known if such an association also exists with subclinical/attenuated forms of psychosis. Addi...

Birth weight, family history of diabetes and diabetes onset in schizophrenia.

Feb 13, 2020

The prevalence of diabetes in schizophrenia is twice that in the general population, but there are few reliable predictors of which individuals will develop glucose dysregulation.To test if abnormal b...

Anomalies in language as a biomarker for schizophrenia.

Feb 13, 2020

After more than a century of neuroscience research, reproducible, clinically relevant biomarkers for schizophrenia have not yet been established. This article reviews current advances in evaluating th...

Impact of Cooling on Lowering the Pain Threshold in Patients Undergoing Sclerotherapy.

Feb 13, 2020

Liquid sclerotherapy is the treatment of choice for telangiectasias. However, pain caused by the procedure is a barrier to treatment adherence by patients.To evaluate the use of skin cooling for the m...

A novel tool showing that perceptions of adverse social relationships in childhood were linked with mental health problems and suicidal experiences: Validation of the English version of the History of Social Punishment (HoSP) scale.

Feb 13, 2020

There is robust evidence for relationships between adverse events experienced in childhood and mental health problems experienced as an adult. However, the measurement of perceptions of different type...

Analyzing the co-localization of substantia nigra hyper-echogenicities and iron accumulation in Parkinson's disease: A multi-modal atlas study with transcranial ultrasound and MRI.

Feb 13, 2020

Transcranial B-mode sonography (TCS) can detect hyperechogenic speckles in the area of the substantia nigra (SN) in Parkinson's disease (PD). These speckles correlate with iron accumulation in the SN ...

Effects of CST3 Gene G73A Polymorphism on Cystatin C in a Prospective Multiethnic Cohort Study.

Feb 13, 2020

G73A polymorphism in the CST3 gene of cystatin C has been associated with Alzheimer's disease, age-related macular degeneration, and cardiovascular disease. However, studies investigating the influenc...

Novel tau filament fold in corticobasal degeneration.

Feb 13, 2020

Corticobasal degeneration (CBD) is a neurodegenerative tauopathy that is characterised by motor and cognitive disturbances. A higher frequency of the H1 haplotype of MAPT, the tau gene, is present in ...

Validity and characteristics of patient-evaluated adherence to medication via smartphones in patients with bipolar disorder: exploratory reanalyses on pooled data from the MONARCA I and II trials.

Feb 13, 2020

Non-adherence to medication is associated with increased risk of relapse in patients with bipolar disorder (BD).To (1) validate patient-evaluated adherence to medication measured via smartphones again...

Complex Combination Pharmacotherapy for Bipolar Disorder: Knowing When Less Is More or More Is Better.

Feb 13, 2020

Combination pharmacotherapy for bipolar disorder is commonplace and often reflects the severity and complexity of the illness and the comorbid conditions frequently associated with it. Across treatmen...

Opposing Changes in the Functional Architecture of Large-Scale Networks in Bipolar Mania and Depression.

Feb 13, 2020

Manic and depressive phases of bipolar disorder (BD) show opposite symptoms in psychomotor, thought, and affective dimensions. Neuronally, these may depend on distinct patterns of alterations in the f...

The Mental Health Crisis Among Teens

Feb 13, 2020

The first signs of a problem started to emerge around 2014: More young people said they felt overwhelmed and depressed in national surveys. College counseling centers reported sharp increases in the n...

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