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Psychiatry General

Neovascular age-related macular degeneration and its association with Alzheimer's disease.

Jan 30, 2020

In developed countries, people of advanced age go permanently blind most often due to age-related macular degeneration, while at global level, this disease is the third major cause of blindness, after...

Negative Evidence for a Role of APH1B T27I Variant in Alzheimer's Disease.

Jan 30, 2020

γ-secretase is a macromolecular complex that catalyzes intramembranous hydrolysis of over 100 membrane-bound substrates. The complex is composed of presenilin (PS1 or PS2), anterior pharynx defect-1(...

Prediction of Freezing of Gait in Patients with Parkinson's Disease by Identifying Impaired Gait Patterns.

Jan 30, 2020

Freezing of gait (FoG) prediction, combined with rhythmic laser cues, may help Parkinson's disease (PD) patients overcome FoG episodes. This study aimed to utilize the impaired gait patterns preceding...

Impact of posttranslational modifications on atomistic structure of fibrinogen.

Jan 30, 2020

Oxidative stress in humans is related to various pathophysiological processes, which can manifest in numerous diseases including cancer, cardiovascular diseases, and Alzheimer's disease. On the atomis...

A survey on machine and statistical learning for longitudinal analysis of neuroimaging data in Alzheimer's disease.

Jan 30, 2020

Recently, longitudinal studies of Alzheimer's disease have gathered a substantial amount of neuroimaging data. New methods are needed to successfully leverage and distill meaningful information on the...

Mental health literacy of ADHD, autism, schizophrenia, and bipolar disorder: a cross-cultural investigation.

Jan 30, 2020

Mental health literacy (MHL) is linked to help-seeking behaviours. Although lay people are not always well aware of mental health conditions, few international campaigns and interventions have been d...

Carrier-Induced Hyporesponsiveness to Pneumococcal Conjugate Vaccines: The Influence of Serotypes, Timing, and Previous Vaccine Dose Unraveled.

Jan 30, 2020

Pneumococcal conjugate vaccines (PCVs) elicit lower immune response against serotypes carried before or at the time of vaccination (hyporesponsiveness) in infants. The limited studies conducted to dat...

Neonatal red blood cell transfusion practices in Switzerland: national survey and review of international recommendations.

Jan 30, 2020

WHAT IS KNOWN ON THE SUBJECT? Red blood cell transfusions are frequently used in the care of newborns, particularly premature infants. Some countries have guidelines regarding preparation, indication ...

Highly Sensitive and Contactless Ammonia Detection Based on Nanocomposites of Phosphate Functionalized Reduced Graphene Oxide/Polyaniline Immobilized on Microstrip Resonators.

Jan 30, 2020

Ammonia is a key-compound in a variety of industrial sectors, including automotive, chemical and food. Its hazardous effects on the environment and human health require the implementation of proper sa...

Association between Adult Attention Deficit/Hyperactivity Disorder and Intravenous Misuse of Opioid and Benzodiazepine in Patients under Opioid Maintenance Treatment: A Cross-Sectional Multicentre Study.

Jan 30, 2020

Intravenous misuse and attention-deficit/hyperactivity disorder (ADHD) are common in patients under opioid maintenance treatment (OMT), who often misuse benzodiazepine (BZD).To explore the rate of adu...

Surgical treatment of fibroids for subfertility.

Jan 30, 2020

Fibroids are the most common benign tumours of the female genital tract and are associated with numerous clinical problems including a possible negative impact on fertility. In women requesting preser...

Blue-blocking glasses as additive treatment for mania: Effects on actigraphy-derived sleep parameters.

Jan 24, 2020

Improvement of sleep is a central treatment goal for patients in a manic state. Blue-blocking (BB) glasses as adjunctive treatment hasten overall recovery from mania. This method is an evolvement from...

[Dynamic neuropathology of tauopathy].

Jan 24, 2020

Tauopathy is defined as abnormal accumulation of aberrantly phosphorylated microtubule-associated protein tau in the central nervous system, best demonstrated by immunocytochemistry using anti-tau ant...

Psychiatric-Based Pediatric ED Visits: Addressing Inadequate Evaluation & Treatment

Jan 24, 2020

Currently configured as urgent medical care facilities, emergency departments (EDs) typically lack the expertise required to appropriately assist psychiatric populations. It is estimated that greater ...

Prediction of Sex-Specific Suicide Risk Using Machine Learning and Single-Payer Health Care Registry Data From Denmark.

Jan 17, 2020

Suicide is a public health problem, with multiple causes that are poorly understood. The increased focus on combining health care data with machine-learning approaches in psychiatry may help advance t...

Considerations by Dutch Psychiatrists Regarding Euthanasia and Physician-Assisted Suicide in Psychiatry: A Qualitative Study.

Jan 17, 2020

Euthanasia and physician-assisted suicide (EAS) in psychiatry are permitted in the Netherlands under certain legal conditions. Doctors may help patients who suffer unbearably and who have no prospect ...

Discontinuing Antidepressants: How Can Clinicians Guide Patients and Drive Research?

Jan 17, 2020

Recent media reports have refocused attention on the syndromic manifestation experienced by some patients as they discontinue their antidepressant medication ("discontinuation syndrome"). This attenti...

Computational Markers of Risky Decision-making for Identification of Temporal Windows of Vulnerability to Opioid Use in a Real-world Clinical Setting.

Jan 17, 2020

Opioid addiction is a major public health problem. Despite availability of evidence-based treatments, relapse and dropout are common outcomes. Efforts aimed at identifying reuse risk and gaining more ...

Smoking tied to worse outcomes after a stroke

Jan 14, 2020

By Lisa Rapaport People who smoke or have recently quit have higher odds of being severely impaired after a stroke than their counterparts who never smoked, a new study su...

FDA Approves Ubrelvy for Acute Migraine Treatment

Jan 08, 2020

Significantly more patients treated with Ubrelvy versus placebo achieved pain freedom two hours post-treatment TUESDAY, Dec. 24, 2019 (HealthDay News) -- Ubrelvy (ubrogepant) tablets have been ap...

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