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Psychiatry General

Preventive Effects of Lithium Carbonate on Antidepressant-Induced Switch During Depressive Episodes: Chinese Data Analysis.

Sep 27, 2021

Some patients experiencing depressive episodes can switch to mania or become mania during treatment with antidepressants. Avoiding a switch is an important part of any therapeutic plan, whether a pati...

Does Post-Traumatic Spectrum Comorbidity Influence Symptom Severity in Bipolar Disorders? A Cross-Sectional Study in a Real-World Setting.

Sep 27, 2021

The present cross-sectional study investigates the relationship between post-traumatic spectrum comorbidity and the severity of symptoms in subjects diagnosed with Bipolar Disorders (BD).In- and outpa...

Isotonic saline causes greater volume overload than electrolyte-free irrigating fluids.

Sep 27, 2021

Systemic absorption of the irrigating fluid used to flush the operating site is a potentially serious complication in several types of endoscopic operations. To increase safety, many surgeons have cha...

Pragmatic Precision Psychiatry-A New Direction for Optimizing Treatment Selection.

Sep 27, 2021

Clinical trials have identified numerous prescriptive predictors of mental disorder treatment response, ie, predictors of which treatments are best for which patients. However, none of these prescript...

Smartphone App for Patients With Psoriasis Proves Beneficial

Sep 24, 2021

“eHealth devices are becoming increasingly popular among dermatologists and their patients,” according to Astrid Schmieder, MD, PhD. “There are many smartphone applications available for managin...

Altered Heschl's gyrus duplication pattern in first-episode schizophrenia.

Sep 20, 2021

Reduced gray matter volumes in the superior temporal gyrus and its subregions, such as Heschl's gyrus (HG) and the planum temporale (PT), have been reported in schizophrenia (Sz). However, it remains ...

Anomalous self-experiences (ASE) in relation to clinical high risk for psychosis (CHRP), childhood trauma and general psychopathology among adolescent and young adult help seekers.

Sep 20, 2021

Anomalous self-experiences (ASE) are suggested as a phenotypic core feature of schizophrenia spectrum disorders and present in at risk samples as well. In our study, we investigated the relation betwe...

The Role of the UPR Pathway in the Pathophysiology and Treatment of Bipolar Disorder.

Sep 20, 2021

Bipolar disorder (BD) is a mood disorder that affects millions worldwide and is associated with severe mood swings between mania and depression. The mood stabilizers valproate (VPA) and lithium (Li) a...

Long-Acting Injectable Antipsychotic Medication Plus Customized Adherence Enhancement in Poor Adherence Patients With Bipolar Disorder.

Sep 20, 2021

People with bipolar disorder (BD) often have difficulty with medication adherence. This pilot trial combined a behavioral customized adherence enhancement (CAE) approach with long-acting injectable (...

Thermotropic liquid crystals in the detection of albumins through a microscopic, spectroscopic and computational approach.

Sep 20, 2021

Liquid crystals (LCs) are a promising system of molecules for biosensing as a transducing agent for detecting protein human serum albumin (HSA). Herein, we investigate the detection of HSA by a liquid...

Smoking and incidence of insomnia: a systematic review and meta-analysis of cohort studies.

Sep 13, 2021

This study investigated the impact of smoking on the incidence of insomnia.Systematic review and meta-analysis of cohort studies.PubMed, EMBASE, Web of Science, Cochrane Library, and OVID were searche...

Meta-Analysis of Quality of Life in Cancer Patients Treated with Immune Checkpoint Inhibitors.

Sep 13, 2021

Trials of immune checkpoint inhibitors (ICIs) have published patient-reported quality of life (QOL), but the size and heterogeneity of this literature can make patient education difficult. This meta-a...

Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations.

Sep 13, 2021

Schizophrenia is a complex and heterogeneous syndrome. Whether quantitative imaging biomarkers can identify discrete subgroups of patients as might be used to foster personalized medicine approaches f...

The association between vitamin D and symptom domains in psychotic disorders: A systematic review.

Sep 13, 2021

Vitamin D deficiency is prevalent among people with psychosis and may play a role in the aetiology of psychotic disorders. However, its impact on clinical symptom severity has not been independently r...

Antipsychotic treatment strategies for acute phase and treatment resistance in schizophrenia: A systematic review of the guidelines and algorithms.

Sep 13, 2021

To summarize the current state of knowledge on antipsychotic treatment strategies for the acute phase and treatment resistance in schizophrenia, we conducted a systematic review of guidelines and algo...

An examination of abstinence social support among recovery home residents with psychiatric comorbidity.

Sep 13, 2021

Although social support is a resource that helps persons in their recovery from substance use disorders, it is not clear whether specific types buffer the effects of stress and optimize outcomes for t...

LncRNA NEAT1 knockdown ameliorates MPP-induced cell injury through miR-519a-3p/SP1 axis in Parkinson's disease.

Sep 13, 2021

Parkinson's disease (PD) is a neurodegenerative disease and is characterized by resting tremor, dementia, and gait disorder. Previous studies have indicated that long noncoding RNA (lncRNA) participat...

Disability and life satisfaction in neurological disorders: The role of depression and perceived cognitive difficulties.

Sep 13, 2021

This study assessed factors associated with disability and life satisfaction in a large cohort of 2246 Australian adults with neurological disorders who completed an online survey of mental health and...

Fasting state is one of the factors associated with plasma levodopa fluctuations during levodopa‒carbidopa intestinal gel treatment.

Sep 13, 2021

Some patients with Parkinson's disease (PD) undergoing levodopa‒carbidopa intestinal gel (LCIG) treatment experience motor fluctuations in the afternoon. The migrating motor complex, a specific peri...

Low peripheral mitochondrial DNA copy number during manic episodes of bipolar disorders is associated with disease severity and inflammation.

Sep 13, 2021

Mitochondria (Mt) are intra-cellular components essential for cellular energy processes whose dysfunction may induce premature cellular senescence and/or inflammation, both observed in bipolar disorde...

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