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Psychiatry General

Sex differences in cognitive function of first-diagnosed and drug-naïve patients with bipolar disorder.

Sep 13, 2021

Bipolar disorder (BD) is a severe mental illness that affects more than 1% the world's population with high recurrence rates and a series of comorbidities. Cognitive dysfunction is an endophenotype of...

Modifiable personal and environmental factors associated with anxiety in family caregivers of children with disabilities: A comparison between parents and grandparents.

Sep 13, 2021

Caregivers of children with disabilities might face high risk of anxiety, but the specific influencing factors may be different between parents and grandparents. This study is to explore the influenci...

Repurposed drugs as adjunctive treatments for mania and bipolar depression: A meta-review and critical appraisal of meta-analyses of randomized placebo-controlled trials.

Sep 13, 2021

Several drugs previously tested in clinical trials and approved for different indications have been repurposed for bipolar disorder. We carried out a systematic meta-review of meta-analyses of randomi...

What Is the Return on Investment of Caring for Complex High-need, High-cost Patients?

Sep 13, 2021

Randomized controlled trials to improve care for complex, high-need, high-cost patients have not consistently demonstrated a relative decrease in acute care utilization or cost savings. However, the V...

A scoping review of the determinants of foetal alcohol spectrum disorder in South Africa: an intersectional perspective.

Sep 13, 2021

Foetal alcohol spectrum disorder (FASD) affects babies born to mothers who consume alcohol while pregnant. South Africa has the highest prevalence of FASD in the world. We review the social determinan...

Estradiol Influences Adenosinergic Signaling and NREM Sleep Need in Adult Female Rats.

Sep 06, 2021

Gonadal steroids and gender are risk factors for sleep disruptions and insomnia in women. However, the relationship between ovarian steroids and sleep is poorly understood. In rodent models, estradiol...

Longitudinal association of apolipoprotein E and sleep with incident dementia.

Sep 06, 2021

Few longitudinal studies have explored the association between apolipoprotein E gene (APOE) status, sleep disturbances, and incident dementia among middle-aged participants.Cox regression analyses exp...

Prolactin levels influenced by antipsychotic drugs in schizophrenia: A systematic review and network meta-analysis.

Sep 06, 2021

Prolactin increase is a common side effect in antipsychotic treatment of schizophrenia, which crucially impacts drug choice and treatment compliance. As previous reviews by our group on this topic hav...

Cognitive clusters in first-episode psychosis.

Sep 06, 2021

Impairments in a broad range of cognitive domains have been consistently reported in some individuals with first-episode psychosis (FEP). Cognitive deficits can be observed during the prodromal stage....

Cortical surface abnormalities are different depending on the stage of schizophrenia: A cross-sectional vertexwise mega-analysis of thickness, area and gyrification.

Sep 06, 2021

Brain magnetic resonance imaging studies have not investigated the cortical surface comprehensively in schizophrenia subjects by assessing thickness, surface area and gyrification separately during th...

Late chronotype predicts more depressive symptoms in bipolar disorder over a 5 year follow-up period.

Sep 06, 2021

There is increasing evidence that bipolar disorder is influenced by circadian timing, including the timing of sleep and waking activities. Previous studies in bipolar disorder have shown that people w...

Ecological Momentary Assessment of Bipolar Disorder Symptoms and Partner Affect: Longitudinal Pilot Study.

Sep 06, 2021

The World Health Organization ranks bipolar disorder (BD) as the 7th leading cause of disability. Although the effects on those with BD are well described, less is reported on the impact of BD on coha...

Increased resting-state brain entropy of parahippocampal gyrus and dorsolateral prefrontal cortex in manic and euthymic adolescent bipolar disorder.

Sep 06, 2021

Alterations of brain signal complexity may reflect brain functional abnormalities. In adolescent bipolar disorder (ABD) distribution of brain regions showing abnormal complexity in different mood stat...

The challenge of COVID-19 for adult men and women in the United States: disparities of psychological distress by gender and age.

Sep 06, 2021

During the COVID-19 pandemic, the prevalence of psychological distress rose from 11% in 2019 to more than 40% in 2020. This study aims to examine the disparities among US adult men and women.We used 2...

By utilizing technology can nursing students gain more confidence and decrease anxiety when communicating with chronically ill patients about their sexual relationship?

Sep 06, 2021

Effective communication is an essential part of nursing care. Nurses need to effectively communicate with patients, families, providers and staff. The purpose of this study was to show how the use of ...

Randomized Noninferiority Trial of Telehealth Delivery of Cognitive Behavioral Treatment of Insomnia Compared to In-Person Care.

Aug 26, 2021

Insomnia is prevalent and is associated with a range of negative sequelae. Cognitive behavioral treatment for insomnia (CBT-I) is the recommended intervention, but availability is limited. Telehealth...

The effectiveness of metacognitive training on impairments in social cognition in patients with schizophrenia: mental health nursing practice in a community mental health center.

Aug 26, 2021

Social cognition is an independent structure from the positive symptoms of schizophrenia and contributes to negative symptoms, neurocognitive impairment, and social functioning.To examine the effectiv...

Obsessive-compulsive symptoms in schizophrenia patients and their first-degree relatives and the association with subclinical psychotic symptoms.

Aug 26, 2021

This study aimed to investigate the presence of obsessive-compulsive symptoms (OCS) in patients being followed for schizophrenia and their first-degree relatives (mother, father, siblings, and childre...

Shape constraint function for artery tracking in ultrasound images.

Aug 26, 2021

Ultrasound guided regional anesthesia (UGRA) has emerged as a powerful technique for pain management in the operating theatre. It uses ultrasound imaging to visualize anatomical structures, the needle...

Erectile Dysfunction and Treatment: An Analysis of Associated Chronic Health Conditions.

Aug 26, 2021

To estimate the association between an erectile dysfunction (ED) diagnosis and other chronic health conditions, as well as, the association between receiving ED treatment and these conditions.Data was...

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