Aug 26, 2021

Valproate (VPA) is a widely used mood stabilizer, but its therapeutic mechanism of action is not understood. This knowledge gap hinders the development of more effective drugs with fewer side effects....

Aug 23, 2021

We investigated the efficacy of the Delirium Team Approach program for delirium prevention after cardiovascular surgery.We retrospectively investigated 256 patients who underwent cardiac or thoracic v...

Aug 23, 2021

The current study examined predictors of outcomes of internet-based cognitive-behavioural therapy (ICBT) for individuals with tinnitus.Secondary analysis of intervention studies.Internet-based guided ...

Aug 23, 2021

This meta-analysis aimed to assess antipsychotic and placebo effects in patients with schizophrenia at the level of symptom factors.A systematic literature search up to June 2020 was undertaken and 62...

Aug 23, 2021

According to the doxastic model, delusions are beliefs. In the metacognitive model, delusions are imaginings mistaken for beliefs. I argue that endorsement of false second-order beliefs could also cre...

Aug 23, 2021

Mitragynine, the major indole alkaloid from Mitragyna speciosa has been reported previously to possess abuse liability. However, there are insufficient data suggesting the mechanism through which this...

Aug 23, 2021

A theory-guided non-experimental, descriptive, correlational design was used to evaluate how entry and passage variables were related to nursing home adjustment for individuals with dementia. Older ad...

Aug 23, 2021

Studies show that more positive relationship satisfaction can mitigate the effects of posttraumatic stress disorder (PTSD) and depression severity on hazardous drinking in military samples. However, p...

Aug 23, 2021

Hepatitis C virus (HCV) causes neuropsychiatric disorders and quality of life impairment, especially in patients with cryoglobulinemic vasculitis (CV). Direct acting antivirals (DAAs) are effective in...

Aug 23, 2021

Antipsychotics and benzodiazepines do not improve delirium. Valproic acid (VPA) has been used recently to treat agitation in delirium.To review the evidence for VPA in the management of Delirium.Syste...

Aug 23, 2021

Symptomatic overlap of depressive episodes in bipolar disorder (BD) and major depressive disorder (MDD) is a major diagnostic and therapeutic problem. Mania in medical history remains the only reliabl...

Aug 23, 2021

Aluminum trichloride (AlCl) exposure was proven to encourage some behavioral deficits and eventually induces anxiety and depression in rodents animals. Therefore, this experiment aimed to scout about ...

Aug 23, 2021

Brain-derived neurotrophic factor (BDNF) has been suggested to play important roles in major depressive disorder (MDD) and antidepressant treatment. The main purpose of this study was to evaluate the ...

Aug 23, 2021

This study aimed to investigate the 1-year changes in neuropsychological test results in older adults with concomitant late-life depression (LLD) and mild cognitive impairment (MCI) according to the p...

Aug 19, 2021

Mismatch negativity (MMN) has been consistently found deficit in schizophrenia, which was considered as a promising biomarker for assessing the impairments in preattentive auditory processing. However...

Aug 19, 2021

Patients with schizophrenia show progressive clinical deterioration. Brain abnormalities have been suggested in these patients, including enlargement of the lateral ventricles, increased cerebrospinal...

Aug 19, 2021

Carriers of the G2019S mutation of LRRK2 provide a great opportunity to investigate the premotor stages of PD. We have studied by serial clinical and DaT-SPECT evaluations a cohort of asymptomatic car...

Aug 19, 2021

Of all types of dementia, Alzheimer's disease is the type that has the highest proportion of cases and is the cause of substantial medical and economic burden. The mechanism of Alzheimer's disease is ...

Aug 19, 2021

The phenotypes of several psychiatric conditions can very closely resemble delirium; the authors describe such presentations as pseudodelirium. However, because the clinical management of these condit...

Aug 19, 2021

The aim of this study was to investigate the relationship of attachment and coping mechanisms with social functioning in patients with bipolar disorder (BD). Sixty-three patients with BD type I and 63...