Aug 05, 2021

Considering most people who inject drugs (PWID) received help with the first injection, understanding the perspective of potential 'initiators' is a priority to inform harm reduction interventions. Th...

Aug 05, 2021

Patient-reported experience measures (PREMs) are recommended for use in evaluating person-centred care. To date, a PREM has not been validated for residential alcohol and other drug (AOD) treatment. U...

Aug 05, 2021

In this era of technology, neurological disorders are the most prevalent disorders in growing population. Alzheimer's and Parkinson's diseases are the most common neurological disorders which are mani...

Aug 05, 2021

Studies of the metal content of metalloproteins in tissues from the human central nervous system (CNS) can be compromised by preparative techniques which alter levels of, or interactions between, meta...

Aug 05, 2021

Impaired olfaction and reduced cholinergic nucleus 4 (Ch4) volume both predict greater cognitive decline in Parkinson's disease (PD). We examined the relationship between olfaction, longitudinal chang...

Aug 05, 2021

The current study evaluated the long-term (52 week) safety and impact on symptom measures of lurasidone (with or without lithium or valproate) for the treatment of bipolar I disorder in Japanese pati...

Aug 05, 2021

Caregivers of patients with bipolar disorder (BD) undergo a considerable amount of burden. In India, family caregivers are the primary source of support and care for their ill relatives. The burden fa...

Aug 05, 2021

This paper provides an overview of results achieved through a whole set of ALARA investigations at the Goesgen Nuclear Power Plant. Doses to workers, the public and the environment have significantly ...

Aug 05, 2021

Psychedelics show promise in treating unipolar depression, though patients with bipolar disorder have been excluded from recent psychedelic trials. There is limited information on the use of classic p...

Aug 05, 2021

A common procedure performed throughout biomedical research is the selection and isolation of biological entities such as organelles, cells and organoids from a mixed population. In this review, we de...

Aug 05, 2021

Automatizing the scoring of the cytokinesis-blocked micronucleus assay spares a lot of valuable time. The dose-effect relationship can be applied reliably for dose estimation, if the quality of the s...

Aug 05, 2021

The respiratory virus responsible for coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected nearly every aspect of life worldwide, claiming th...

Aug 04, 2021

“Cognitive impairment in patients with multiple sclerosis (MS) is related to functional network changes, based on previous cross-sectional research,” explains Marijn Huiskamp, MSc. “My colleague...

Aug 02, 2021

A minimally invasive retroperitoneal pancreatic necrosectomy (MIRPN) decreases morbidity and mortality from necrotizing acute pancreatitis. However, the impact of MIRPN on patient reported outcomes (P...

Aug 02, 2021

Individuals with schizophrenia spectrum disorders (SSD) are at heightened risk for exposure to stressful life events which can lead to increased sensitivity to stress and a dysregulated stress respons...

Aug 02, 2021

Pathological Internet use (but only with respect to gaming) is classified as mental disorder in the ICD-11. However, there is a large group of adolescents showing excessive Internet use, which may rat...

Aug 02, 2021

Neurocognitive symptoms exert the most influence on treatment outcomes over the course of schizophrenia, starting from the first-episode of psychosis (FEP) onwards. Our aim was to analyze the neurocog...

Aug 02, 2021

Language abnormalities are a core symptom of schizophrenia-spectrum disorders and could serve as a potential diagnostic marker. Natural language processing enables quantification of language connected...

Aug 02, 2021

Patients with more severe mental health symptoms are treated in acute inpatient psychiatric units (AIPUs), but the functioning of these units throughout Spain has been challenged by the COVID-19 pande...

Aug 02, 2021

Bipolar disorder (BD) is associated with marked parenchymal brain loss in a significant fraction of patients. The lack of necrosis in postmortem examination suggests an apoptotic process. Emerging evi...