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Psychiatry General

Kainate receptor modulation of glutamatergic synaptic transmission in the CA2 region of the hippocampus.

Jul 26, 2021

Kainate (KA) receptors (KARs) are important modulators of synaptic transmission. We studied here the role of KARs on glutamatergic synaptic transmission in the CA2 region of the hippocampus where the ...

Evidence for the association between physiological and emotional states in adolescents and young adults without psychopathology under ecologically valid conditions.

Jul 26, 2021

Well-powered studies on the physiological concomitants underlying affect and its regulation during emerging adulthood are warranted to provide novel insight into mental health. The association between...

Cognitive Behavior Therapy for Depression From an Evolutionary Perspective.

Jul 26, 2021

Evolutionary medicine attempts to solve a problem with which traditional medicine has struggled historically; how do we distinguish between diseased states and "healthy" responses to disease states? F...

Disgust uniquely predicts coping and interpersonal processes beyond anxiety and dysphoria in the context of naturalistic stressors.

Jul 26, 2021

Disgust is theorized to serve a unique function of motivating avoidance of noxious stimuli and setting interpersonal boundaries to prevent contamination. Research has established the relevance of disg...

"Why can't you sit still?"The effect of daily physical activity on childhood inattention/hyperactivity and the educational gender gap.

Jul 26, 2021

Despite the compelling evidence of the long-run consequences of childhood inattention/hyperactivity and harmful side effects of stimulant medication, relatively little is known about accessible non-ph...

Marital Adjustment in Patients with Cancer: Association with Psychological Distress, Quality of Life, and Sleep Problems.

Jul 22, 2021

Marital adjustment plays a key role in the physical and psychosocial wellbeing. We conducted a cross-sectional study to evaluate marital adjustment and its association with psychological distress, sui...

Incidence and duration of common early-onset adverse events in randomized controlled trials of solriamfetol for treatment of excessive daytime sleepiness in obstructive sleep apnea and narcolepsy.

Jul 22, 2021

This post-hoc analysis characterized the weekly incidence and overall duration of common early-onset treatment-emergent adverse events (TEAEs) during solriamfetol treatment.Participants (obstructive s...

A comparison of cognitive performance in the Suffolk County cohort and their unaffected siblings.

Jul 22, 2021

People diagnosed with schizophrenia and other psychoses demonstrate impaired neuropsychological performance. Their unaffected siblings exhibit mild impairments relative to unrelated controls, suggesti...

Altered effective connectivity within an oculomotor control network in individuals with schizophrenia.

Jul 22, 2021

Rapid inhibition or modification of actions is a crucial cognitive ability, which is impaired in persons with schizophrenia (SZP). Primate neurophysiology studies have identified a network of brain re...

Unilateral rhomboid intercostal and subserratus plane block application for analgesia after laparoscopic cholecystectomy surgery :a quasi-experimental study.

Jul 22, 2021

Interfascial plane block applications can be used for postoperative pain after laparoscopic surgery. We aimed to investigate the effect of ultrasound-guided unilateral rhomboid intercostal and subserr...

Effects of transcranial direct current stimulation on experimental pain perception: A systematic review and meta-analysis.

Jul 22, 2021

Many studies have examined the effectiveness of transcranial direct current stimulation (tDCS) on human pain perception in both healthy populations and pain patients. Nevertheless, studies have yielde...

Maternal corticosteroids and depression during gestation and decreased fetal heart rate variability.

Jul 22, 2021

Maternal depression during gestation is an adverse factor in fetal brain development that manifests in later childhood behavioral problems. Fetal heart rate variability (FHRV) mediated by parasympathe...

Behavioral mediators of stress-related mood symptoms in adolescence & young adulthood.

Jul 22, 2021

Stress is a risk factor for unipolar and bipolar mood disorders, but the mechanisms linking stress to specific symptoms remain elusive. Behavioral responses to stress, such as impulsivity and social w...

Assessment of Spaceflight Medical Conditions' and Treatments' Potential Impacts on Behavioral Health and Performance.

Jul 22, 2021

Long-duration space exploration missions will pose significant risks to the physical and behavioral health and performance of the crew. We documented the presence and frequency of (1) behavioral healt...

Multiscale neural modeling of resting-state fMRI reveals executive-limbic malfunction as a core mechanism in major depressive disorder.

Jul 22, 2021

Major depressive disorder (MDD) represents a grand challenge to human health and society, but the underlying pathophysiological mechanisms remain elusive. Previous neuroimaging studies have suggested ...

Beyond Functional Impairment: Redefining Favorable Outcome in Patients with Subarachnoid Hemorrhage.

Jul 22, 2021

For outcome assessment in patients surviving subarachnoid hemorrhage (SAH), the modified Rankin scale (mRS) represents the mostly established outcome tool, whereas other dimensions of outcome such as ...

Validation of PROMIS-29 domain scores among adult burn survivors: A National Institute on Disability, Independent Living, and Rehabilitation Research Burn Model System Study.

Jul 22, 2021

Patient-reported outcomes are important for understanding recovery after burn injury, benchmarking service delivery and measuring the impact of interventions. PROMIS-29 domains have been validated for...

Effect of long working hours and insomnia on depressive symptoms among employees of Chinese internet companies.

Jul 19, 2021

In China, long working hours and insomnia are relatively common among internet company employees. Considering that both can affect mental health, we examined their independent and interaction effects ...

High incidence of acute self-reported sleep disturbances in patients following arthroscopic-assisted knee surgery.

Jul 19, 2021

To evaluate the self-reported incidence of sleep disturbances, defined as ≤7 hours of sleep per 24-hour period, in patients undergoing arthroscopic-assisted knee surgery.Patients who underwent art...

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank.

Jul 19, 2021

Here, we investigated the genetics of weighted functional brain network graph theory measures from 18,445 participants of the UK Biobank (44-80 years). The eighteen measures studied showed low herita...

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