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Psychiatry General

Spared performance but increased uncertainty in schizophrenia: Evidence from a probabilistic decision-making task.

Jul 19, 2021

Aberrant attribution of salience to in fact little informative events might explain the emergence of positive symptoms in schizophrenia and has been linked to belief uncertainty. Uncertainty is though...

Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.

Jul 19, 2021

While the pathophysiology of schizophrenia has been extensively investigated using homogenized postmortem brain samples, few studies have examined changes in brain samples with techniques that may att...

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.

Jul 19, 2021

Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurot...

Healthcare professionals' experiences of the barriers and facilitators to paediatric pain management in the community at end-of-life: A qualitative interview study.

Jul 19, 2021

Inadequate pain management in community paediatric palliative care is common. Evidence to inform improved pain management in this population is limited.To explore the barriers and facilitators to paed...

Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies.

Jul 19, 2021

Cocaine use entails severe health- and social-related harms globally. Treatment options for cocaine dependence are highly limited. Benefits of cannabinoids for addiction have been documented, making i...

Lithium therapy and weight change in people with Bipolar Disorder: a systematic review and meta-analysis.

Jul 19, 2021

Lithium remains the gold standard maintenance treatment for Bipolar Disorder (BD). However, weight gain is a side effect of increasing relevance due to its metabolic implications. We conducted a syste...

Bipolar disorder and Susac syndrome: a case report.

Jul 19, 2021

Susac-syndrome is a rare autoimmune disease that manifests with mood alterations in up to 15% of cases and is usually treated with corticosteroids. We present the case of a 41-year-old woman with a fi...

Reliability, validity and psychometric properties of the Greek version of the Altman self rating mania scale.

Jul 19, 2021

Although self-rating mania scales have been developed, a lack of such instruments validated for the Greek population is noted. This study aims to examine the validity, reliability and psychometric pro...

Differences in late adolescent psychopathology among youth with histories of co-occurring abuse and neglect experiences.

Jul 19, 2021

Knowledge about the impacts of child abuse and neglect (CAN) experiences on late adolescent psychopathology has been limited by a failure to consider the frequent co-occurrence of CAN types and potent...

Internet-delivered cognitive-behaviour therapy (ICBT) for obsessive-compulsive disorder when delivered as routine clinical care: A phase IV clinical trial.

Jul 19, 2021

Cognitive-behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD), but many patients experience difficulty accessing this treatment. Internet-delivered CBT (ICBT) enh...

Clients in context: Environment, class, race, and therapists' perceptions of generalized anxiety disorder.

Jul 19, 2021

Evidence-based practice necessitates the inclusion of client identity and contextual information when conceptualizing diagnosis.To examine how therapists' perceptions of Generalized Anxiety Disorder i...

The acute effects of aerobic exercise on sleep in patients with unipolar depression: a randomized controlled trial.

Jul 15, 2021

Insomnia increases the risk of negative disease trajectory, relapse, and suicide in patients with depression. We aimed at investigating the effects of a single bout of aerobic exercise, performed afte...

Ketamine Treatment for Depression in Patients With a History of Psychosis or Current Psychotic Symptoms: A Systematic Review.

Jul 15, 2021

Ketamine shows rapid and robust antidepressant effects in clinical studies. Psychotic features are an exclusion criterion in most ketamine treatment studies based on the assumption that psychosis wil...

Intervertebral foramen injection of plerixafor attenuates neuropathic pain after chronic compression of the dorsal root ganglion: Possible involvement of the down-regulation of Nav1.8 and Nav1.9.

Jul 15, 2021

Neuropathic pain is a common chronic pain condition with major impact on quality of life. However, its physiopathologic mechanism remains unknown and pain management is still a challenge. Accumulating...

Transdermal delivery of flurbiprofen from polyoxypropylene-polyoxyethylene block copolymer stabilized reduced graphene oxide to manage pain in spondylitis: In vitro and in vivo studies.

Jul 15, 2021

Ankylosing spondylitis is an inflammatory arthritic disease affecting the spine and large joints, causing severe pain. Flurbiprofen is widely used as an oral formulation (tablet dosage form) to contro...

Prevalence and predictors of the persistence and incidence of adolescent internet addiction in Mainland China: A two-year longitudinal study.

Jul 15, 2021

Internet addiction (IA), which can have different development patterns, is considered a serious problem among adolescents. Due to the increasing number of adolescent internet users in Mainland China, ...

Perception of memory performance after first seizure in patients with and without an epilepsy diagnosis.

Jul 15, 2021

Memory complaints in patients with epilepsy have been well-studied. Although memory complaints are commonly reported by patients with chronic epilepsy, to date, few studies exist on memory complaints ...

The impact of the COVID-19 pandemic on suicide ideation and suicide attempts in a sample of psychiatric inpatients.

Jul 15, 2021

There has been little research reported regarding both suicide ideation and suicide attempts during the COVID-19 pandemic and government lockdown restrictions in Italy, one of the countries most affec...

Parkinson's disease patients may have higher rates of Covid-19 mortality in Iran.

Jul 15, 2021

Parkinson's disease (PD) patients may be at increased risk of Covid-19 mortality due to the nature of their disease or underlying conditions.The information of 12,909 Covid-19 patients who were hospit...

Using complexity-entropy planes to detect Parkinson's disease from short segments of haemodynamic signals.

Jul 15, 2021

There is emerging evidence that analysing the entropy and complexity of biomedical signals can detect underlying changes in physiology which may be reflective of disease pathology. This approach can b...

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