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Psychiatry General

Transitional challenges in a two-plus-two nursing program: Phenomenology of student experiences.

Jul 12, 2021

With the concept of self-efficacy as a theoretical framework, this qualitative research study explored the academic, social and psychological challenges faced by students transferring from a community...

Brain volume in chronic ketamine users - relationship to sub-threshold psychotic symptoms and relevance to schizophrenia.

Jul 08, 2021

Ketamine may model aspects of schizophrenia arising through NMDA receptor activity deficits. Although acute ketamine can induce effects resembling both positive and negative psychotic symptoms, chroni...

Stability of schizophrenia diagnosis in a ten-year longitudinal study on first episode of non-affective psychosis: conclusions from the PAFIP cohort.

Jul 08, 2021

To evaluate the ten-year stability of schizophrenia diagnosis in a cohort of first-episode psychosis (FEP) patients and the factors associated with it.Changes in diagnosis of 209 FEP patients were des...

Comorbid alcohol-related problems and suicidality disproportionately impact men and emerging adults among individuals with depressive symptoms.

Jul 08, 2021

Depressive disorders are common among adults with alcohol use disorder and with suicidality; however, demographic differences in comorbid alcohol use disorder, binge drinking, and suicidality are unde...

Association between social network characteristics and prevalent and incident depression: The Maastricht Study.

Jul 08, 2021

Social network characteristics may provide a novel non-pharmaceutical target for the prevention of depression. We investigated the temporal association of a broad range of structural and functional so...

Translational evidence for lithium-induced brain plasticity and neuroprotection in the treatment of neuropsychiatric disorders.

Jul 08, 2021

Increasing evidence indicates lithium (Li) efficacy in neuropsychiatry, pointing to overlapping mechanisms that occur within distinct neuronal populations. In fact, the same pathway depending on which...

Enlightened: addressing circadian and seasonal changes in photoperiod in animal models of bipolar disorder.

Jul 08, 2021

Bipolar disorders (BDs) exhibit high heritability and symptoms typically first occur during late adolescence or early adulthood. Affected individuals may experience alternating bouts of mania/hypomani...

Interactions and implications of Fuzzy-Trace theory for risk taking behaviors in bipolar disorder.

Jul 08, 2021

According to Fuzzy-Trace Theory (FTT), qualitative, bottom-line, "gist" reasoning leads to less risk taking and more mature decision-making, less easily swayed by emotions than quantitative, detail-or...

Facial emotion recognition in major depressive disorder: A meta-analytic review.

Jul 08, 2021

Major depressive disorder (MDD) has been associated with difficulties in social and interpersonal functioning. Deficits in emotion processing may contribute to the development and maintenance of inter...

Inflexibly sustained negative affect and rumination independently link default mode network efficiency to subclinical depressive symptoms.

Jul 08, 2021

Aberrant DMN connectivity and activity have been robustly linked to Major Depressive Disorder (MDD) and risk for depression. This link has mostly been explained in terms of rumination, a form of negat...

Thalamocortical interactions in cognition and disease: the mediodorsal and anterior thalamic nuclei.

Jul 05, 2021

The mediodorsal thalamus (MD) and anterior thalamic nuclei (ATN) are two adjacent brain nodes that support our ability to make decisions, learn, update information, form and retrieve memories, and fin...

Involvement of Vascular Endothelial Growth Factor in schizophrenia.

Jul 05, 2021

Vascular endothelial growth factor (VEGF), which acts as an angiogenic and neurotrophic factor, is involved the regulation of cerebral blood volume and flow in Schizophrenia (SCZ). Several evidence in...

A systematic review of stigma interventions for providers who treat patients with substance use disorders.

Jul 05, 2021

Stigma surrounding substance use disorders (SUDs) is a frequently cited barrier to treatment engagement. Research consistently demonstrates that healthcare professionals' attitudes towards patients wi...

Fish Oil Supplementation Alters Emotion-Generated Corticolimbic Functional Connectivity in Depressed Adolescents at High-Risk for Bipolar I Disorder: A 12-Week Placebo-Controlled fMRI Trial.

Jul 05, 2021

To evaluate the effects of fish oil (FO), a source of the omega-3 polyunsaturated fatty acids (n-3 PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on emotion-generated corticolimbic ...

Efficacy of Endoxifen, a Protein kinase C inhibitor for acute and mixed mania: Some concerns worth considering.

Jul 05, 2021

We read the article by Ahmad et al with great interest. The study concluded that endoxifen is efficacious and safe in patients with acute manic episodes with/without mixed features. However, we are wo...

Early detection of bipolar disorders and treatment recommendations for help-seeking adolescents and young adults: Findings of the Early Detection and Intervention Center Dresden.

Jul 05, 2021

Early identification and intervention of individuals with risk factors for or subtle prodromal symptoms of bipolar disorders (BD) may improve the illness course and prevent adverse long-term consequen...

Momentary and longitudinal relationships of mindfulness to stress and anxiety among Chinese elementary school students: mediations of cognitive flexibility, self-awareness, and social environment.

Jul 05, 2021

Mindfulness could benefit elementary school students' mental health, but little is known about the mechanisms of mindfulness in the elementary school context. The current studies explored mindfulness'...

Measures of emotion regulation: Convergence and psychometric properties of the difficulties in emotion regulation scale and emotion regulation questionnaire.

Jul 05, 2021

Investigating unique and shared aspects of measures of emotion regulation (ER) advances our understanding of ER as a multidimensional construct. This study aimed to investigate psychometric properties...

Self-stigma, severity of psychopatology, dissociation, parental style and comorbid personality disorder in patient with neurotic spectrum disorders Part 1: Relationships between self-stigma and clinical, psychosocial and demograph.

Jul 05, 2021

Self-stigma represents a process of accepting negative social prejudices with a consequent negative impact on many areas of the patient's life (self-concept, social and work functioning, relationships...

Digital cognitive-behavioural therapy for insomnia compared with digital patient education about insomnia in individuals referred to secondary mental health services in Norway: protocol for a multicentre randomised controlled trial.

Jul 01, 2021

Insomnia is highly prevalent in outpatients receiving treatment for mental disorders. Cognitive-behavioural therapy for insomnia (CBT-I) is a recommended first-line intervention. However, access is li...

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