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Psychiatry General

Factors behind a remarkable increase in adolescent psychiatric inpatient treatment between 1980 and 2010 - a nationwide register study.

Jul 01, 2021

This register-based study aimed to evaluate trends in adolescent psychiatric inpatient care using nationwide data from three consecutive decades.The study population ( 17,112) comprised all Finnish ci...

Extrapolation of Efficacy and Dose Selection in Pediatrics: A Case Example of Atypical Antipsychotics in Adolescents With Schizophrenia and Bipolar I Disorder.

Jul 01, 2021

Pediatric labeling information for novel atypical antipsychotics can be significantly delayed as the result of time lag between initial drug approval in adults and the completion of pediatric clinical...

Brain iron assessment in patients with First-episode schizophrenia using quantitative susceptibility mapping.

Jul 01, 2021

Decreased serum ferritin level was recently found in schizophrenia. Whether the brain iron concentration in schizophrenia exists abnormality is of research significance. Quantitative susceptibility ma...

Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial.

Jul 01, 2021

Ketamine has emerged as a rapid-acting antidepressant. While ongoing treatment can prevent relapse, concerns exist regarding long-term exposure.We conducted a randomized trial to examine the feasibili...

'Pediatric Bipolar Disorder' rates are still lower than claimed: a re-examination of eight epidemiological surveys used by an updated meta-analysis.

Jul 01, 2021

'Pediatric bipolar disorder' (PBD) is a controversial diagnosis with varying rates of clinical diagnosis. A highly cited meta-analysis (Van Meter et al. 2011) of a dozen epidemiological surveys sugges...

Early Life Stress and Chronobiological Rhythms Desynchronization: Possible Impact on Mood Symptoms and Suicidal Ideation in Bipolar Disorder.

Jul 01, 2021

The study aimed at investigating the potential impact of early stressful events on the clinical manifestations of bipolar disorder (BD). A sample of 162 adult individuals with BD was assessed using th...

Resilience in severe mental disorders: correlations to clinical measures and quality of life in hospitalized patients with major depression, bipolar disorder, and schizophrenia.

Jul 01, 2021

To evaluate resilience in severe mental disorders and correlate it with clinical measures and quality of life.Resilience (Resilience Scale, RS) and quality of life (WHOQOL-BREF questionnaire) were pro...

Subthreshold stimulation intensity is associated with greater clinical efficacy of intermittent theta-burst stimulation priming for Major Depressive Disorder.

Jul 01, 2021

Intermittent theta-burst stimulation priming (iTBS-P) can improve clinical outcome of patients with Major Depressive Disorder (MDD) who do not show early benefit from 10 Hz stimulation of left dorsol...

Effects of Long-Duration Home Isolation Linked to the COVID-19 Pandemic on Mental Health of Adolescent Athletes.

Jul 01, 2021

To assess whether adolescent athletes were affected or not in terms of mental health by the long duration at home linked to isolation enforced during the COVID-19 pandemic.The study included 940 team ...

Examining Characteristics Linked With Poor Outcomes in Opioid Prescribing

Jun 30, 2021

“In recent decades, the medical community has become acutely aware of the dangers posed by prescription opioids and their contribution to the opioid epidemic,” explains David R. Foster, PharmD, FC...

Effect of exercise training on improving sleep disturbances: a systematic review and meta-analysis of randomized control trials.

Jun 28, 2021

Exercise training has beneficial effects on various aspects of health. This study aimed to investigate the effect of exercise training on the improvement of sleep disturbances using systematic review ...

Mental health literacy in Ghana: Implications for religiosity, education and stigmatization.

Jun 28, 2021

Research on Mental Health Literacy (MHL) has been growing internationally. However, the beliefs and knowledge of Ghanaians about specific mental disorders have yet to be explored. This vignette study ...

Perinatal iron deficiency as an early risk factor for schizophrenia.

Jun 28, 2021

Growing evidence indicates that a suboptimal intrauterine environment confers risk for schizophrenia. The developmental model of schizophrenia posits that aberrant brain growth during early brain deve...

A characterization of the effects of minocycline treatment during adolescence on structural, metabolic and oxidative stress parameters in a maternal immune stimulation model of neurodevelopmental brain disorders.

Jun 28, 2021

Minocycline (MIN) is a tetracycline with antioxidant, anti-inflammatory and neuroprotective properties. Given the likely involvement of inflammation and oxidative stress (IOS) in schizophrenia, MIN ha...

Oxygen vacancy engineering of TaO-based resistive memories by Zr doping for improved variability and synaptic behavior.

Jun 28, 2021

Resistive switching (RS) devices are promising forms of non-volatile memory. However, one of the biggest challenges for RS memory applications is the device-to-device (D2D) variability, which is relat...

Quality of Life Assessment in Older Adults with Dementia: A Systematic Review.

Jun 28, 2021

In the absence of a cure, dementia is often managed by minimizing risk factors contributing to quality of life (QOL). Attitudes to dementia in older adults may differ from those in relatively younger ...

Effect of aromatherapy on sleep quality of adults and elderly people: A systematic literature review and meta-analysis.

Jun 28, 2021

The purpose of this study was to characterize studies on aromatherapy and sleep quality and to identify the measurable effects of aromatherapy on the sleep quality of adults and elderly people.We sear...

Differential item functioning of the Beck Anxiety Inventory in a rural, multi-ethnic cohort.

Jun 28, 2021

Evaluating measurement bias is vital to ensure equivalent assessment across diverse groups. One approach for evaluating test bias, differential item functioning (DIF), assesses item-level bias across ...

The clinical effectiveness and safety of traditional Chinese medicine uremic clearance granule combined with high-flux hemodialysis in the treatment of uremic pruritus: A protocol for systematic review and meta analysis.

Jun 24, 2021

Skin pruritus is a common complication in patients with uremia. When the hemodialysis time of patients is extended, and the probability of skin pruritus is greater. Patients often have the symptoms of...

Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness.

Jun 24, 2021

Schizophrenia is a complex heritable disorder associated with many genetic variants, each with a small effect. While cortical differences between patients with schizophrenia and healthy controls are c...

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