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Psychiatry General

Duration of Untreated Psychosis in First-Episode Psychosis is not Associated With Common Genetic Variants for Major Psychiatric Conditions: Results From the Multi-Center EU-GEI Study.

May 10, 2021

Duration of untreated psychosis (DUP) is associated with clinical outcomes in people with a diagnosis of first-episode psychosis (FEP), but factors associated with length of DUP are still poorly under...

Digital phenotyping adherence, feasibility, and tolerability in outpatients with schizophrenia.

May 10, 2021

Digital phenotyping has potential for use as an objective and ecologically valid form of symptom assessment in clinical trials for schizophrenia. However, there are critical methodological factors tha...

Efficacy and safety of antipsychotic treatments for schizophrenia: A systematic review and network meta-analysis of randomized trials in Japan.

May 10, 2021

We examined the efficacy and safety of using antipsychotic medication for schizophrenia using only randomized trials of antipsychotic for schizophrenia conducted in Japan to avoid the biological and e...

Effects of addiction science on conceived freewill and responsibility.

May 10, 2021

Although there is speculation that medicalization of addiction undermines conceived agency, only relatively modest effects have been reported. Research participants generally have ideas about addictio...

Monitoring the early aggregatory behaviour and size of Aβ in the absence & presence of metal ions using dynamic light scattering.

May 10, 2021

Aβ is an amyloidogenic peptide found within senile plaques extracted from those who died with a diagnosis of Alzheimer's disease. The potent neurotoxicity of this peptide is related to its propensity...

Discovery research and development history of the dopamine D receptor partial agonists, aripiprazole and brexpiprazole.

May 10, 2021

Otsuka Pharmaceutical Co., Ltd. successfully developed the first dopamine D receptor partial agonist approved for schizophrenia, the antipsychotic aripiprazole (Abilify ). The drug was approved for th...

Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania.

May 10, 2021

Formal thought disorders (FTD) are a hallmark diagnostic feature of schizophrenia (SZ) and (bipolar) mania (MA). FTD can be separated into positive (pFTD) and negative dimensions. It is unclear whethe...

Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder.

May 10, 2021

Several lines of research suggest that impairments in long-term potentiation (LTP)-like synaptic plasticity might be a key pathophysiological mechanism in schizophrenia (SZ) and bipolar disorder type ...

Use of virtual reality in the inpatient rehabilitation of COVID-19 patients.

May 10, 2021

Use of virtual reality (VR) in healthcare has expanded in recent years. The challenges faced by patients with prolonged COVID-19-related hospitalizations - social isolation, disability, neurologic seq...

[INFLUENCE OF COMBINED ERADICATION AND PROKINETIC THERAPY ON CLINICAL MANIFESTATIONS, PSYCHOLOGICAL STATUS AND QUALITY OF LIFE OF PATIENTS WITH FUNCTIONAL DYSPEPSIA - POSTPRANDIAL DISTRESS SYNDROME: RANDOMIZED PROSPECTIVE STUDY].

May 10, 2021

Functional dyspepsia - postprandial distress-syndrome (FD-PDS) is one of the most common reasons for seeking medical attention of general practitioners, internists and gastroenterologists worldwide. S...

LipiDiDiet multinutrient

May 10, 2021

Specialists agreement feelings on dementia avoidance recommended that movement from gentle psychological weakness (MCI) to dementia could be decreased by thoughtfulness regarding modifiable danger fac...

NORMALIZING EFFECT OF ELECTROMAGNETIC STIMULATION ON BLOOD QUANTITATIVE INDICES IN DEPRESSED RATS ON THE BACKGROUND OF OXYTOCIN.

May 10, 2021

Depression is linked to systemic inflammation. There is an association between blood cell count and/or hematological inflammatory markers with depression symptoms. Oxytocin reduces the activity of bra...

Validation strategies for subtypes in psychiatry: A systematic review of research on autism spectrum disorder.

May 10, 2021

Heterogeneity within autism spectrum disorder (ASD) is recognized as a challenge to both biological and psychological research, as well as clinical practice. To reduce unexplained heterogeneity, subty...

Dementia in Latin America

May 10, 2021

This study states that Across Latin American and Caribbean nations (LACs), the battle against dementia faces squeezing difficulties, like heterogeneity, variety, political precariousness, and financia...

High APP in Down syndrome

May 10, 2021

This study states that Late clinical preliminaries focusing on amyloid beta (Aβ) and tau in Alzheimer's infection (AD) presently can't seem to exhibit adequacy. Evaluating the theories for AD pathoge...

Theory‐based specification

May 07, 2021

This review states that Dementia is at present perhaps the most squeezing health‐care issues, with an overall rising predominance because of the maturing of the populace and the shortfall of a thera...

Solomon Carter Fuller

May 07, 2021

This study states that Racial inequality remains a considerable problem in society worldwide. For Black and African‐American individuals, it is a sobering and painful reality that has persisted for ...

Circulating metabolites

May 07, 2021

This study states that Dementia, including Alzheimer's infection (AD), is a quickly developing medical services issue. Vascular sickness is a significant supporter of AD pathology.1 Moreover, satisfac...

Risk and protective factors

May 07, 2021

In this review Alzheimer's infection (AD) has been identified with the statement of amyloid beta (Aβ) peptide plaques in mind tissues that may cause neurodegeneration.1 Stroke, particularly ischemic ...

Altered lipidostasis hypothesis

May 07, 2021

This study states that Adenosine triphosphate–restricting tape carrier subfamily A part 7 (ABCA7) is important for the new science pertinent to Alzheimer's illness (AD) that has risen up out of the ...

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