Apr 22, 2021

In this article, we describe an extension of general anaesthesia - beyond facilitating surgery - to the relief of suffering during dying. Some refractory symptoms at the end of life (pain, delirium, d...

Apr 22, 2021

The extant literature is inconsistent over whether manic symptoms in First Episode Psychosis (FEP) impact on its development and trajectory. This study addressed: 1) Does Duration of Untreated Illness...

Apr 22, 2021

Bipolar disorder is a psychiatric illness that strikes between mania and depression, caused by both genetic and environmental factors. It is the sixth leading cause of disability worldwide and 3% of t...

Apr 22, 2021

Major depressive disorder (MDD) is one of the most common psychiatric disorders. Various clinical studies have shown that the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid, robust...

Apr 22, 2021

Persistent genital arousal disorder/genito-pelvic dysesthesia (PGAD/GPD) is a distressing condition characterized by persistent, unwanted sensations of genital arousal (eg, feelings of being on the ve...

Apr 22, 2021

Worry about COVID-19 is an important cognitive component and manifestation of COVID-19-related anxiety. It has a social dimension and is shaped by various social factors.We employ original data from a...

Apr 22, 2021

Forensic DNA typing typically relies on the length-based (LB) separation of PCR products containing short tandem repeat loci (STRs). Massively parallel sequencing (MPS) elucidates an additional level ...

Apr 20, 2021

“Psoriasis has been linked with a variety of systemic disorders, including cardiovascular (CV) conditions, which may predispose patients to developing dementia,” explains Megan Lam, BSc. “While ...

Apr 19, 2021

Despite neuropsychiatric outcomes of SARS-CoV-2 infection are now under close scrutiny, psychoneuroimmunological characteristics of COVID-19 and precise pathophysiology of neuropsychiatric manifestati...

Apr 19, 2021

Narcolepsy type 1 (NT1) is a chronic neurological disorder having a strong association with HLA-DQB1*0602, thereby suggesting an immunological origin. Increased risk of NT1 has been reported among chi...

Apr 19, 2021

Psychiatric problems, such as stress and anxiety disorders, are encountered among healthcare professionals fighting epidemics. Considering that COVID-19 suddenly became a pandemic and healthcare profe...

Apr 19, 2021

Impaired event-related potential (ERP) indices reflecting performance monitoring systems have been consistently reported in patients with schizophrenia. However, whether these impairments exist from t...

Apr 19, 2021

Individuals with schizophrenia exhibit widespread cortical thinning associated with illness severity and deficits in cognition. However, intact cortical thickness (CTh) may serve as a protective facto...

Apr 19, 2021

Neuropsychological impairments represent a central feature of psychosis-spectrum disorders. It is characterized by a great both within- and between-subjects variability (i.e. cognitive heterogeneity),...

Apr 19, 2021

Long-term survival following hematopoietic stem cell transplant (HSCT) in childhood continues to improve and patients are thus increasingly faced with the late effects of treatment. Infertility is ver...

Apr 19, 2021

Although recent studies explored using microbial succession during decomposition to estimate the postmortem interval (PMI) and postmortem submersion interval (PMSI), there is currently no published re...

Apr 19, 2021

Carbon tetrachloride (CT) is highly toxic and recalcitrant in groundwater. In recent years, zero-valent aluminum (ZVAl) is highly reductive but limited by its surface passivation film. One of the effe...

Apr 15, 2021

Narcolepsy is a sleep disorder with the main manifestations of excessive daytime sleepiness, cataplexy, sleep paralysis, sleep hallucinations, and nighttime sleep disturbance. It is still not fully re...

Apr 15, 2021

Accumulation of senile plaques mainly composed of neurotoxic amyloid-beta peptide (Aβ) is a pathological hallmark of Alzheimer's disease (AD). Sestrin2 inducible by various types of stressors is know...

Apr 15, 2021

Parkinson's Disease patients undergo time-consuming programming to refine stimulation parameters after deep brain stimulation surgery.To assess whether the use of the advanced functions of a patient's...