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Psychiatry General

[Diagnostics and Therapy 24/7? Artificial Intelligence as a Challenge and Opportunity in Psychiatry and Psychotherapy].

Mar 04, 2021

The aim of the article is to enable a fundamental understanding of the potentials and requirements of Artificial Intelligence (AI) for psychiatrists in the present and for the development of future wo...

Omega-3 fatty acid in ultra-high-risk psychosis: A systematic review based on functional outcome.

Mar 04, 2021

Among different types of poly unsaturated fatty acids, omega-3 fatty acids (FA) play a substantial role in brain development and functioning. This review was designed to evaluate and synthesize availa...

The effect of N-acetylcysteine on bipolar depression: a systematic review and meta-analysis of randomized controlled trials.

Mar 04, 2021

The current pharmacotherapy of bipolar depression often presents limited efficacy and increased risk for adverse events. N-acetylcysteine (NAC) has been suggested as potentially effective and well-tol...

Associations between the cortisol awakening response and patient-evaluated stress and mood instability in patients with bipolar disorder: an exploratory study.

Mar 04, 2021

The Cortisol Awakening Response (CAR) measured as the transient increase in cortisol levels following morning awakening appears to be a distinct feature of the HPA axis. Patients with bipolar disorder...

Melanopsin-mediated pupillary responses in bipolar disorder-a cross-sectional pupillometric investigation.

Mar 04, 2021

Visible light, predominantly in the blue range, affects mood and circadian rhythm partly by activation of the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). The li...

Storytelling: One arts-based learning strategy to reflect on clinical placement. An integrative review.

Mar 04, 2021

Storytelling is one method of arts-based learning. The pedagogy of arts-based learning integrates the arts into another topic to enhance learning. Nursing students' experiences of clinical placement a...

Impacts on Quality of Life with Escitalopram Monotherapy and Aripiprazole Augmentation in Patients with Major Depressive Disorder: A CAN-BIND Report.

Mar 04, 2021

Many individuals with major depressive disorder (MDD) do not respond to initial antidepressant monotherapy. Adjunctive aripiprazole is recommended for treatment non-response; however, the impacts on q...

Computerized Adaptive Screen for Suicidal Youth

Mar 03, 2021

The rate of suicide among US adolescents is rising, but still, most adolescents don't receive any mental health services. The question is that can the use of a computerized adaptive screen reliably pr...

Therapeutic effects of Silexan on somatic symptoms and physical health in patients with anxiety disorders: A meta-analysis.

Mar 01, 2021

A meta-analysis was performed to examine therapeutic effects of Silexan on somatic symptoms, including insomnia/fatigue, and physical health in patients with anxiety disorders. Five randomized, placeb...

Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder.

Mar 01, 2021

Identifying brain processes involved in the risk and development of mental disorders is a major aim. We recently reported substantial interindividual heterogeneity in brain structural aberrations amon...

The prevalence and features of schizophrenia among individuals with gambling disorder.

Mar 01, 2021

Few studies have analyzed the comorbid presence of gambling disorder (GD) with schizophrenia, its sociodemographic correlates and clinical implications. This study estimated the prevalence of the dual...

Cortical expression of the RAPGEF1 gene in schizophrenia: investigating regional differences and suicide.

Mar 01, 2021

Rap guanine nucleotide exchange factor 1 (RAPGEF1) is involved in cell adhesion and neuronal migration. Previously we found lower RAPGEF1 mRNA levels in Brodmann's area (BA) 9 in subjects with schizop...

Problematic internet use: The effect of comorbid psychopathology on treatment outcomes.

Mar 01, 2021

Problematic Internet use (PIU) behaviours involve one's maladaptive Internet use and have been often described as secondary manifestations of pre-existing psychopathology. Furthermore, different profi...

Hand therapists' perspectives and practices related to musculoskeletal pain: A biopsychosocial lens.

Mar 01, 2021

While the biopsychosocial model is advocated for pain management, biomedical approaches continue to dominate in practice. Understanding musculoskeletal clinicians' perspectives and practices related t...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.

Mar 01, 2021

Neurofilament light chain (NFL) level in biofluids is a sensitive measure of axonal damage and a promising biomarker in neurodegenerative diseases. In Parkinson's disease (PD), NFL can distinguish PD ...

Levodopa affects spike and local field synchronisation in the pedunculopontine nucleus of a rat model of Parkinson's disease.

Mar 01, 2021

The pedunculopontine nucleus (PPN) undergoes significant anatomic and electrophysiological alterations in Parkinson's disease (PD), severely impacting locomotion. However, the effect of 6-hydroxydopam...

Real-World Patterns of Utilization and Costs Associated with Second-Generation Oral Antipsychotic Medication for the Treatment of Bipolar Disorder: A Literature Review.

Mar 01, 2021

Treatment with second-generation antipsychotics (SGAs) for bipolar disorder, including bipolar I disorder (BD-I), is common. This review evaluated real-world utilization patterns with oral SGAs in the...

Manic-Depressive Cycles in Bipolar Disorder: Clinical and Treatment Implications.

Mar 01, 2021

Cycle patterns of bipolar disorders (BDs) have been previously shown to be associated with clinical characteristics and response to lithium salts. Here, we evaluated the distribution of different type...

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