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Psychiatry General

Treating Episodic Migraine Patients with Erenumab 140 mg

Feb 23, 2021

Patients with episodic migraine (EM) are treated with prophylactic medicines. These preventives are helpful to reduce the headache's severity, frequency, or associated disease. The patients in a Phase...

Genetic Influence for Familial Clustering of Amyotrophic Lateral Sclerosis

Feb 23, 2021

Amyotrophic lateral sclerosis (AML) is a rare and progressive neurological disease. It hinders voluntary movements like talking, chewing, and walking. This study aims to assess the disease phenotype a...

Generalised anxiety disorders

Feb 23, 2021

The main objective of this study is to Summed up uneasiness problem and indications are related with poor physical, passionate and social working and incessant essential and intense consideration visi...

Role of sociodemographic characteristics in Children

Feb 23, 2021

Depression is related with lower instructive fulfillment, however there has been little examination of long haul instructive directions in huge associates with analyzed sorrow. To portray the instruct...

Mental health during the COVID-19

Feb 23, 2021

The main objective of this study is to understand The impacts of Covid sickness 2019 (COVID-19) on the populace's emotional well-being and prosperity are probably going to be significant and durable. ...

Developmental disabilities and psychiatric disorders

Feb 22, 2021

Intellectual and developmental disabilities (IDDs) and mental issues habitually co-happen. Albeit each has been related with negative results, their consolidated impact has infrequently been examined....

Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.

Feb 22, 2021

Despite major advances, there remains a need for novel anesthetic drugs or drug combinations with improved efficacy and safety profiles. Here, we show that inhibition of cAMP-phosphodiesterase 4 (PDE4...

Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins.

Feb 22, 2021

The major problems of morphine use in the clinic are its tolerance and dependence. This study aimed to investigate the effect of suvorexant, a dual orexin receptor antagonist, on morphine-induced depe...

Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.

Feb 22, 2021

In recent years, a number of emergency department (ED)-based interventions have been developed to provide supports and/or treatment linkage for people who use opioids. However, there is limited resear...

High-fat feeding causes inflammation and insulin resistance in the ventral tegmental area in mice.

Feb 22, 2021

The reward system plays an important role in the pathogenesis of not only drug addiction, but also diet-induced obesity. Recent studies have shown that insulin and leptin receptor signaling in the ven...

Adverse childhood experiences and problematic smartphone use among college students: Findings from a pilot study.

Feb 22, 2021

There has been a tremendous increase in the use of smartphones among college students and alongside the benefits there is growing concern over problematic/addictive smartphone use (PSU). Among the mos...

Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.

Feb 22, 2021

In recent years, a number of emergency department (ED)-based interventions have been developed to provide supports and/or treatment linkage for people who use opioids. However, there is limited resear...

The psychiatric effects of ketogenic diet therapy on adults with chronic epilepsy.

Feb 22, 2021

Patients with epilepsy are known to exhibit high rates of comorbid psychiatric disorders such as depression, anxiety, and other mood disorders. Little is known about the psychiatric effects of a ketog...

Symptom Burden and Medication Use Among Patients With Nontuberculous Mycobacterial Lung Disease.

Feb 22, 2021

Respiratory diseases caused by nontuberculous mycobacteria (NTM) have become a significant concern for patients and healthcare providers. We aimed to compare symptoms experienced during the past two w...

Objective sleep data as predictors of cognitive decline in dementia with Lewy Bodies and Parkinson's disease.

Feb 22, 2021

Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB) prognosis depends on cognitive function evolution. Sleep disorders, as objectivated by polysomnography (PSG), are intimately connected with...

An anatomical knowledge-based MRI deep learning pipeline for white matter hyperintensity quantification associated with cognitive impairment.

Feb 22, 2021

Recent studies have confirmed that white matter hyperintensities (WMHs) accumulated in strategic brain regions can predict cognitive impairments associated with Alzheimer's disease (AD). The knowledge...

Gut flora-targeted photobiomodulation therapy improves senile dementia in an Aß-induced Alzheimer's disease animal model.

Feb 22, 2021

Emerging evidence suggests that the gut microbiota plays an important role in the pathological progression of Alzheimer's disease (AD). Photobiomodulation (PBM) therapy is believed to have a positive ...

Reduced Activity in an Inpatient Liaison Psychiatry Service During the First Wave of the COVID-19 Pandemic: Comparison With 2019 Data and Characterization of the SARS-CoV-2 Positive Cohort.

Feb 22, 2021

The COVID-19 pandemic led to changes in the way that healthcare was accessed and delivered in the United Kingdom (UK), particularly during the peak of the first lockdown period (the "first wave") beg...

A Review of the Relationship of the Cerebrospinal Fluid Changes During the Dysregulation of Parathyroid Hormone With Psychiatric or Neurological Manifestations.

Feb 22, 2021

It is established that normal calcium and vitamin D concentrations are maintained in the body through parathyroid hormone (PTH), a signaling molecule secreted from parathyroid glands. A massive role i...

Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease: A Meta-Analysis of Mood Effects.

Feb 22, 2021

This meta-analysis examines mood changes after bilateral subthalamic deep brain stimulation (STN-DBS) in patients with Parkinson's disease (PD). Deep brain stimulation improves motor outcomes in Parki...

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