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Psychiatry General

Cortical mediation of relationships between dopamine receptor D2 and cognition is absent in youth at risk of bipolar disorder.

Feb 04, 2021

Bipolar disorder is associated with cognitive deficits and cortical changes for which the developmental dynamics are not well understood. The dopamine D2 receptor (DRD2) gene has been associated with ...

Comparison of regional brain deficit patterns in common psychiatric and neurological disorders as revealed by big data.

Feb 04, 2021

Neurological and psychiatric illnesses are associated with regional brain deficit patterns that bear unique signatures and capture illness-specific characteristics. The Regional Vulnerability Index (R...

Early Clinical Results of the Tolerability, Safety, and Efficacy of Autologous Platelet-Rich Plasma Administration in Erectile Dysfunction.

Feb 04, 2021

Platelet-rich plasma (PRP) is useful in the treatment of different conditions and diseases as it contains concentrated levels of many growth factors.The aim of this study was to investigate the effect...

Treatment retention and abstinence of patients with substance use disorders according to addiction severity and psychiatry comorbidity: A six-month follow-up study in an outpatient unit.

Feb 04, 2021

The impact of psychiatric comorbidity and addiction features throughout the course of addiction has been widely studied. This is a naturalistic study conducted in an outpatient unit, where treatment f...

Relationship between physical and mental health comorbidities and COVID-19 positivity, hospitalization, and mortality.

Feb 04, 2021

Understanding the association between separate and combined mental and physical health diagnoses and COVID-19 outcomes is greatly needed to address the severity of illness.Data on 24,034 patients scre...

Automated quantification of opioid withdrawal in neonatal rat pups using Ethovision® XT software.

Feb 04, 2021

Chronic prenatal exposure to opioids often causes fetal opioid dependence that leads to neonatal opioid withdrawal syndrome (NOWS) shortly after delivery. Rat models of NOWS often require quantifying ...

Tranexamic Acid Has No Effect on Post-operative Hemarthrosis or Pain Control Following ACL Reconstruction Using Bone Patella Tendon Bone Autograft: A Double-Blinded Randomized Control Trial.

Feb 04, 2021

The purpose of this double-blinded randomized controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patella tendon-bone (BTB) ACLR with...

A Clinical Trial of a Video Intervention Targeting Opioid Disposal After General Surgery: A Feasibility Study.

Feb 04, 2021

The opioid epidemic continues and although some initiatives have shown promise in reducing the number of opiates prescribed, few studies have focused on education of general surgery patients about hom...

Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review.

Feb 04, 2021

Polygenic risk scores (PRS) are predictors of the genetic susceptibility to diseases, calculated for individuals as weighted counts of thousands of risk variants in which the risk variants and their w...

A2ARs-D2R Heterodimerization in Schizophrenia

Feb 02, 2021

As indicated by the adenosine theory of schizophrenia, the traditionally related hyperdopaminergic state might be auxiliary to a deficiency of capacity of the adenosinergic framework. Such a hypo aden...

MVPA to Neuroplasticity-based CCT in ROP

Feb 02, 2021

Twenty years of studies recommend that modernized intellectual preparing (CCT) affects psychological improvement and the reclamation of cerebrum action. By the by, singular reaction to CCT stays heter...

DAT Function Fluctuates Across Sleep/Wake State

Feb 02, 2021

Creating interest has been found in using lysergic destructive diethylamide (LSD) in mental investigation and treatment. Regardless, no high level examinations have surveyed conceptual and autonomic e...

ADHD & Explore/Exploit Trade-off

Feb 02, 2021

The ability to maximize rewards and minimize the costs of obtaining them is vital to making advantageous explore/exploit decisions. Exploratory decisions are theorized to be greater among individuals ...

NMDAR Modulation Causes Antidepressant-like Effects

Feb 02, 2021

This research states that Dysregulation of the glutamatergic framework and its receptors in average prefrontal cortex (mPFC) has been ensnared in significant burdensome problems. Ongoing preclinical e...

Acute Dose-dependent LSD Effects in Healthy Subjects

Feb 01, 2021

Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric research and therapy. However, no modern studies have evaluated subjective and autonomic effects of different an...

Beta-caryophyllene Inhibits CUD by PPARα & PPARγ Activation

Feb 01, 2021

The following research states that Cocaine misuse keeps on being a genuine medical issue around the world. Regardless of exceptional exploration, there is still no FDA-affirmed drug to treat cocaine u...

Inhibition Effects of FAAH by JNJ-42165279 in SAD

Feb 01, 2021

This examination expresses that The endocannabinoid structure is thought to check out the rule of fear and anxiety responses, the protected system, and torture knowledge. N-arachidonoylethanolamine (a...

Gadd45b Associated with Cocaine-related Behaviors

Feb 01, 2021

This research states that The narcotic scourge has earned a significant part of the public's consideration as of late, however dependence on psychostimulants keeps on speaking to a generous extent of ...

Construct and criterion validity of patient-reported outcomes (PROs) for depression: A clinimetric comparison.

Feb 01, 2021

A number of patient-reported outcomes (PROs) have been developed but insufficient attention has been devoted to the assessment of their clinimetric properties. Clinimetrics, the science of clinical me...

The psychological impact of COVID-19 and restrictive measures in the world.

Feb 01, 2021

In a short time, the COVID-19 pandemic turned into a global emergency. The fear of becoming infected and the lockdown measures have drastically changed people's daily routine. The aim of this study is...

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