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Psychiatry General

Perspectives on the Impact of Digital Interventions on Loneliness: Qualitative Focus Group with Lonely Happify Health Users During COVID-19.

Jan 28, 2021

Loneliness is a growing area of concern, attracting attention as a public health concern due to its association with a variety of psychological and physical health problems. However, interventions tar...

Emotional processes in binge drinking: A systematic review and perspective.

Jan 28, 2021

Binge drinking is a widespread alcohol consumption pattern commonly engaged by youth. Here, we present the first systematic review of emotional processes in relation to binge drinking. Capitalizing on...

Perspectives on the Impact of Digital Interventions on Loneliness: Qualitative Focus Group with Lonely Happify Health Users During COVID-19.

Jan 28, 2021

Loneliness is a growing area of concern, attracting attention as a public health concern due to its association with a variety of psychological and physical health problems. However, interventions tar...

The Parkinson's Disease DNA Variant Browser.

Jan 28, 2021

Parkinson's disease (PD) is a genetically complex neurodegenerative disease with ~20 genes known to contain mutations that cause PD or atypical parkinsonism. Large-scale next-generation sequencing pro...

Chemical similarity assisted search for acetylcholinesterase inhibitors: Molecular modeling and evaluation of their neuroprotective properties.

Jan 28, 2021

Alzheimer's disease (AD) is an obstinate and progressive neurodegenerative disorder, mainly characterized by cognitive decline. Increasing number of AD patients and the lack of promising treatment str...

Long-term study of ropinirole patch in Parkinson's disease patients with/without basal l-dopa.

Jan 28, 2021

A dopamine agonist patch could be an important treatment option for Parkinson's disease. This study evaluated the long-term efficacy and safety of the ropinirole hydrochloride patch. The steady state ...

Case Report: Paliperidone Palmitate in the Management of Bipolar I Disorder With Non-compliance.

Jan 28, 2021

Medication non-adherence is prevalent in patients with bipolar disorder (BD). Long-acting injectable antipsychotics (LAIAs) are widely used to improve compliance with treatment. This study aimed to i...

Pluripotential Risk and Clinical Staging: Theoretical Considerations and Preliminary Data From a Transdiagnostic Risk Identification Approach.

Jan 28, 2021

Most psychiatric disorders develop during adolescence and young adulthood and are preceded by a phase during which attenuated or episodic symptoms and functional decline are apparent. The introduction...

A specific neural substrate predicting current and future impulsivity in young adults.

Jan 28, 2021

Impulsivity (rash action with deleterious outcomes) is common to many psychiatric disorders. While some studies indicate altered amygdala and prefrontal cortical (PFC) activity associated with impulsi...

Effects of high fat diet-induced obesity and pregnancy on prepartum and postpartum maternal mouse behavior.

Jan 28, 2021

Obesity before and during pregnancy negatively affects the mental and physical health of the mother. A diet high in fat also increases the risk for anxiety, depression and cognitive dysfunction. We ex...

Emotional processes in binge drinking: A systematic review and perspective.

Jan 28, 2021

Binge drinking is a widespread alcohol consumption pattern commonly engaged by youth. Here, we present the first systematic review of emotional processes in relation to binge drinking. Capitalizing on...

Perspectives on the Impact of Digital Interventions on Loneliness: Qualitative Focus Group with Lonely Happify Health Users During COVID-19.

Jan 28, 2021

Loneliness is a growing area of concern, attracting attention as a public health concern due to its association with a variety of psychological and physical health problems. However, interventions tar...

Developmental vascular malformations in EPAS1-gain-of-function syndrome.

Jan 28, 2021

EPAS1, encoding HIF-2α, mutations were previously identified in a syndrome of multiple paragangliomas, somatostatinoma, and polycythemia. HIF-2α, when dimerized with HIF-1β, acts as an angiogenic t...

Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19.

Jan 28, 2021

We evaluated the incidence, distribution, and histopathologic correlates of microvascular brain lesions in patients with severe COVID-19. Sixteen consecutive patients admitted to the intensive care un...

First Report of Resistance to Ivermectin in Parascaris univalens in Iceland.

Jan 28, 2021

Horses in Iceland have been isolated for more than 1,000 yr but still harbor a similar range of gastrointestinal parasites as do horses across the world. The long isolation of the horses and their par...

Anxiety sensitivity and substance use: Differential levels across individuals primarily using opioids, cannabis, or stimulants.

Jan 28, 2021

The purpose of the current study was to compare levels of anxiety sensitivity (AS) across a treatment-seeking sample of individuals primarily using opioids, stimulants, or cannabis. Consistent with th...

Expanding access to methadone treatment in Ohio through federally qualified health centers and a chain pharmacy: A geospatial modeling analysis.

Jan 28, 2021

In the United States, methadone provision for opioid use disorder (OUD) occurs at opioid treatment programs (OTPs). Ohio recently enacted a policy to expand methadone administration to Federally Quali...

Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review.

Jan 28, 2021

Polygenic risk scores (PRS) are predictors of the genetic susceptibility to diseases, calculated for individuals as weighted counts of thousands of risk variants in which the risk variants and their w...

α1-Na/K-ATPase Inhibition Reverses Elongation of Neurons

Jan 27, 2021

This research states that Angelman condition (AS) is a neurodevelopmental problem brought about by the deficiency of capacity of the maternal UBE3A quality. The hippocampus is quite possibly the most ...

MDMA-induced Changes in Serotonergic Hallucinogens Specificity

Jan 27, 2021

In this examination, the specialists tried the theory that these changes are not explicit for stimulants but rather that they can be actuated by monoaminergic incitement utilizing the non-stimulating ...

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