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Pain Management

ASCO: Gastric Cancer Patients Respond to Trastuzumab Deruxtecan

Jun 02, 2020

Overall survival also extended with conjugate treatment In a small, phase II trial, patients with advanced gastric cancer were far more likely to respond to conjugate therapy with trastuzumab deruxte...

How COVID-19 Has Impacted the Opioid Crisis

May 07, 2020

When it comes to rates of infection and addiction, both the coronavirus pandemic and the opioid epidemic disproportionately impact the poorest and most vulnerable members of society. As physicians, it...

Many Legal Marijuana Products Too Strong for Treating Pain

Apr 03, 2020

FRIDAY, April 3, 2020 (HealthDay News) -- Legally dispensed marijuana products have stronger concentrations of tetrahydrocannabinol (THC) and cannabidiol (CBD) than needed for chronic pain relief, acc...

Late-Life Depression Severity Varies by Race, Ethnicity

Mar 27, 2020

FRIDAY, March 27, 2020 (HealthDay News) -- Significant racial and ethnic differences have been identified in late-life depression (LLD) severity, symptom burden, and depression care, according to a st...

Inhaled Cannabis for Headache & Migraine

Mar 23, 2020

Today, a substantial proportion of medical cannabis users report using cannabis to manage headache and migraine, claiming that it is effective. However, research on the effectiveness of cannabis for t...

Opioid Use After ED Visits for Acute Pain

Feb 26, 2020

While the frequency of short-term side effects of opioids are well-known, the long-term risks of opioid use are inadequately quantified. For a study published in Annals of Emergency Medicine, my colle...

Phosphates in medications: Impact on Dialysis Patients


Feb 13, 2020

Maintaining phosphorus balance in in-center hemodialysis (ICHD) patients is problematic despite recommended dietary restriction, dialysis, and phosphate binder use. Rarely is P content in prescribed m...

Neuroendocrine Effects of Naltrexone Versus Nalmefene

Feb 13, 2020

Naltrexone and nalmefene are approved for the treatment of alcohol use disorders, in different countries. Naltrexone is also approved for the treatment for opioid use disorders, most recently in a dep...

Estimating the impact of wide scale uptake of screening and medications for opioid use disorder in US prisons and jails.

Feb 13, 2020

Medications for opioid use disorder (OUD) are the most effective treatment for OUD, but uptake of these life-saving medications has been extremely limited in US prisons and jail settings, and limited ...

Trajectories of Retention in Opioid Agonist Therapy

Feb 13, 2020

Long-term engagement in opioid agonist therapy (OAT) has been consistently associated with reduced risk for morbidity and mortality in people with opioid use disorder (OUD). However, the dynamic natur...

Psychosocial Factors Associated with Sleep Quality and Duration Among Older Adults with Chronic Pain.

Feb 13, 2020

Sleep complaints are common among older adults with chronic pain. Because of the risk of significant side effects, sleep medications are not recommended as first-line treatments. Little is known about...

Brain MRIs ID Racial Differences in Pain Response

Feb 11, 2020

TUESDAY, Feb. 11, 2020 (HealthDay News) -- Racial differences in pain may be rooted in life experience, rather than intrinsic biology, according to a study published online Feb. 3 in Nature Human Beha...

Opioid Crisis Along Mexico's Northern Border: Treatment Needs Mexican Opioid Crisis.

Feb 10, 2020

Heroin production for external markets and low rates of use in Mexico have had a long history. A recent shift toward an increase in use and related problems calls for the evaluation of treatment needs...

Opioid Prescribing Patterns of Oral and Maxillofacial Surgery Residents

Feb 10, 2020

The aim of this study was to report on the opioid prescribing patterns of oral and maxillofacial surgery residents for routine office-based procedures.A survey was sent to current resident members of ...

The impact of the abuse-deterrent reformulation of extended-release OxyContin on prescription pain reliever misuse and heroin initiation.

Feb 10, 2020

The introduction of abuse-deterrent OxyContin in 2010 was intended to reduce its misuse by making it more tamper resistant. However, some studies have suggested that this reformulation might have had ...

Nonpharmacological Adjunctive Treatment for Postpartum Women with Opioid Use Disorder

Feb 10, 2020

Over the past decade, opioid use disorder (OUD) among pregnant women has increased by over 400%. Although medication assisted treatment (MAT) provides necessary care for women with OUD, effective adju...

Mental health conditions and the risk of chronic opioid therapy among patients with rheumatoid arthritis: a retrospective veterans affairs cohort study.

Feb 10, 2020

Patients with rheumatoid arthritis (RA) often receive opioid analgesics for pain management. We examined the association between mental health conditions and the risk of chronic opioid therapy.A retro...

FDA Approves Ubrelvy for Acute Migraine Treatment

Jan 08, 2020

Significantly more patients treated with Ubrelvy versus placebo achieved pain freedom two hours post-treatment TUESDAY, Dec. 24, 2019 (HealthDay News) -- Ubrelvy (ubrogepant) tablets have been ap...

Overdose, Relapse After Buprenorphine Discontinuation High

Dec 27, 2019

The longer patients continue with buprenorphine treatment, the lower their risk of adverse outcomes.   THURSDAY, Dec. 26, 2019 (HealthDay News) -- Buprenorphine treatment may be needed ...

Ubrogepant Relieves Pain, Symptoms of Acute Migraine

Dec 04, 2019

WEDNESDAY, Dec. 4, 2019 (HealthDay News) -- The percentage of patients with migraine reporting freedom from pain is higher for those receiving ubrogepant than those receiving placebo, according to a s...

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