Previously, we showed that abnormal levels of bioactive lipids in bronchoalveolar lavage fluid (BALF) from infants with cystic fibrosis (CF) correlated with early structural lung damage.To e...
MicroRNAs that are overexpressed in cystic fibrosis (CF) bronchial epithelial cells (BEC) negatively regulate CFTR and nullify the beneficial effects of CFTR modulators. We hypothesized that...
Cystic fibrosis is characterized by dehydration of the airway surface liquid layer with persistent mucus obstruction. immune responses are often manifested as increased mucous cell density ...
Patients with cystic fibrosis (CF) have frequent infectious complications requiring nephrotoxic medications, necessitating monitoring of renal function. Although adult studies have suggested...
Cystic fibrosis transmembrane conductance receptor (CFTR)-related disease is diagnosed in patients affected by CFTR dysfunction but who do not fully meet the CF diagnostic criteria. Only 2% ...
Genetic carrier screening has the potential to identify couples at risk of having a child affected with an autosomal recessive or X-linked disorder. However, the current prevalence of carrie...
Stress is ubiquitous for bacteria and can convert a subpopulation of cells into a dormant state known as persistence, in which cells are tolerant to antimicrobials. These cells revive rapidl...
Cystic fibrosis (CF) is genetic disease that affects the patient's lungs, pancreas, liver, kidney and intestine and lacks sulfatase enzyme, which lead to mucopolysaccharidosis. Colistin sulf...
Bacteria colonising the lungs of cystic fibrosis (CF) patients encounter high selective pressures. Hypermutation facilitates adaptation to fluctuating environments, and hypermutator strains ...
Patients with cystic fibrosis (CF) experience multiple pulmonary exacerbations throughout their lifetime, resulting in repeated antibiotic exposure and hospital admissions. Reliable diagnost...
Aspergillus is a mould that is ubiquitous in nature and may lead to a variety of infectious and allergic diseases depending on the host's immune status or pulmonary structure. Invasive pulmo...
Immunoreactive Trypsinogen (IRT) is a protein-based pancreatic proenzyme that has an important role in protein digestion in humans. In human body, once IRT present in the small intestine, th...
Agency says it is still too early to know how severe this year's flu season will be. MONDAY, Dec. 30, 2019 (HealthDay News) -- Flu continues to spread throughout the United States and h...
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