Jul 10, 2024

Denosumab significantly reduced the relative risk (RR) of fractures more than bisphosphonates in pretreated women with osteoporosis. Denosumab significantly reduced the relative risk (RR) of fr...

Oct 23, 2023

Osteoporosis, a systemic bone disease defined by decreased bone mass and deterioration of bone microarchitecture, is becoming a global concern. Nodakenin (NK) is a furanocoumarin-like compound isolate...

Oct 09, 2023

Silencing type information regulator homolog 1 (SIRT1) is a class of nicotinamide adenine dinucleotide (NAD) dependent deacetylases, which is the convergence point of important physiological processes...

Sep 25, 2023

Trabecular bone score (TBS) is a FRAX®-independent risk factor for fracture prediction. TBS values increase from cranial to caudal, with the following mean differences between TBS and individual lumb...

Jul 17, 2023

There are approximately 13 million patients with osteoporosis in Japan; however, only 20% of them receive treatment. This study compared the 4-year continuation rates of osteoporosis drugs at differen...

Jun 05, 2023

Computed tomography-based vertebral attenuation values (CT-based HU) have been shown to correlate with T-scores on DEXA scan; and have been acknowledged as an independent factor for predicting fragili...

May 08, 2023

Persistence with denosumab in male patients has not been adequately investigated, although poor denosumab persistence is associated with a significant risk of rebound vertebral fractures.We retrospect...

May 01, 2023

Osteoporosis is a global health issue, and modifiable behavioural factors need to be identified in childhood to reduce the risk of osteoporosis in later life. The aim of this study was to investigate ...

Apr 24, 2023

Women with severe metabolic syndrome (MetS) are at risk for greater structural knee osteoarthritis progression. Metabolic syndrome (MetS)—a clustering of abdominal obesity and other metabolic...

Feb 27, 2023

Some older patients who suffered from both conditions (disc degeneration and osteoporosis) have higher surgical risks and longer postoperative recovery times. Understanding the relation between disc d...

Feb 27, 2023

Healthy sleep signifies a good physical and mental state of the body. However, factors such as inappropriate work schedules, medical complications, and others can make it difficult to get enough sleep...

Feb 13, 2023

Postmenopausal women are at significant risk for osteoporotic fractures due to their rapid bone loss. Half of all postmenopausal women will get an osteoporosis-related fracture over their lifetime, wi...

Dec 05, 2022

Previous evidence suggests that bisphosphonates may improve glycemic control. The present meta-analysis, comprising seven studies with 1,233,844 participants, demonstrated that bisphosphonate use was ...

Dec 05, 2022

Previous evidence suggests that bisphosphonates may improve glycemic control. The present meta-analysis, comprising seven studies with 1,233,844 participants, demonstrated that bisphosphonate use was ...

Aug 31, 2022

Although they are beneficial in reducing inflammation, glucocorticoids have been linked with many well-known adverse effects, and their use often elicits fierce debate. Glucocorticoids (GCs) ha...

Nov 29, 2021

“For many years, there have been serious concerns among the medical and lay communities surrounding the use of sunscreen and other sun-protective measures with regard to their potentially detrimenta...

Nov 22, 2021

Psoriasis is a dermatological condition often associated with systemic comorbidities such as arthritis. Because of the vital role of treatment compliance in improvement in patients' condition and the ...

Jul 22, 2021

Cognitive decline and osteoporosis often coexist and some evidence suggests a causal link. However, there are no data on the longitudinal relationship between cognitive decline, bone loss and fracture...

Jul 22, 2021

To prospectively examine the association between arthritis and type 2 diabetes (T2D) in the Chinese population and confirm this association through a comprehensive meta-analysis of cohort studies.Data...

Jul 22, 2021

Spinal motion is facilitated by a "three joint complex", two facet joints and one intervertebral disc at each spinal level. Both the intervertebral discs and facet joints are subject to natural age-re...