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Osteoporosis

Distinguishing PHPT- from Estrogen Withdrawal-Related Osteoporosis

Aug 10, 2020

“Primary hyperparathyroidism (PHPT)-related osteoporosis is one of the most frequent causes of secondary osteoporosis, and it frequently occurs in postmenopausal women, with a prevalence of up to 1%...

Low Bone Marrow Associated with Larger Muscle Fat Areas

Aug 10, 2020

While previous studies have shown bone and muscle to interact, little is known regarding the role of fat within bone and muscle, explains Andy Kin On Wong, PhD. Dr. Wong and colleagues hypothesized th...

Considering Osteoporosis During the COVID-19 Pandemic

Aug 08, 2020

In these unprecedented times, the changes in the model of healthcare towards chronic disease may be here to stay. Individuals with chronic conditions, such as frail older and immune-compromised peop...

Denosumab Improves Bone Density in RA/Osteoporosis Dual Dx

Aug 08, 2020

Improvements apparent after 12 months. Among patients diagnosed with rheumatoid arthritis who also fulfill the criteria for osteoporosis, treatment with denosumab appears to improve or maintain bon...

Assessing Beyond DXA in Older Adults With Fractures

Aug 06, 2020

Although dual-energy X-ray absorptiometry (DXA)-measured BMD at the hip and spine is widely used to diagnose osteoporosis, 10%-20% of patients who sustain osteoporosis-related fractures are reported t...

Incidence of Hip Fracture Decreased From 1970 to 2010

Aug 03, 2020

The incidence of hip fracture decreased from 1970 to 2010, with reductions in smoking and heavy drinking coincident with this decrease, according to a study published online July 27 in JAMA Internal M...

Nottingham Hip Fracture Score: Predicts Outcomes in Hospitalized Hip Fracture Patients

Aug 03, 2020

The Nottingham Hip Fracture Score (NHFS) has been developed for predicting 30-day and 1-year mortality after hip fracture. In an effort to test whether NHFS can also predict other adverse events. D...

Second BMD Measurement Not Beneficial for Identifying Hip Fracture

Aug 02, 2020

A second bone mineral density (BMD) assessment about three years after initial measurement does not improve discrimination beyond baseline BMD value alone for women who do and do not experience subseq...

Atopic Eczema in Patients with Osteoporosis

Jun 02, 2020

Patients with atopic eczema have an increased risk for fracture, especially major osteoporotic fractures, according to a recent study published in the Journal of Allergy and Clinical Immunology. Ka...

Osteoporotic Fracture Treatment Considerations

Jun 02, 2020

Approaches to osteoporosis management differ between and within countries. In the UK, for example, approaches differ between those organizations that place the primary emphasis on cost-effectiveness (...

Osteoporotic Fracture Trends

May 30, 2020

Reports of Medicare data suggest that osteoporotic fracture incidence in the United States—which had been declining—is not only no longer declining, but may be on the rise, explains Setareh Aria W...

Race & Fracture Risk Prediction in Postmenopausal Women

May 10, 2020

Prior research indicates that fractures, as the most clinically relevant endpoint of osteoporosis, are associated with excess disability and mortality. Although the Fracture Risk Assessment Tool (FRAX...

Comparison between clinical and ultrasound assessment of the ankle region in juvenile idiopathic arthritis.

Apr 28, 2020

To compare frequency of joint and tendon disease on ultrasound (US) and clinical examination (CE), and to investigate agreement between US and CE in ankles with clinically active juvenile idiopathic a...

Patient global assessment and radiographic progression in early arthritis: 3-year results from the ESPOIR cohort.

Apr 28, 2020

To determine if patient global assessment (PGA), as part of Boolean-based definition of remission and individually considered, over the first year of disease course had a significant relationship with...

Differential requirement for CCR6 in IL-23-mediated skin and joint inflammation.

Apr 28, 2020

CC chemokine receptor 6 (CCR6) is important for the trafficking of IL-17A-producing γδ T cells and required for the development of psoriasiform dermatitis (PsD) in an IL-23 intradermal injection mod...

The water extract of "Jiao Mei Gu" attenuates the lipopolysaccharide-induced inflammatory response via inhibiting NF-κB activity in mice.

Apr 24, 2020

Jiao Mei Gu (JMG) is a type of Dong plant widely growing in Dong autonomous counties, Hunan province, China. As a type of traditional herbal medicine, JMG has been used to treat inflammatory-related d...

Network pharmacology approach to elucidate possible action mechanisms of Sinomenii Caulis for treating osteoporosis.

Apr 24, 2020

Sinomenii Caulis (SC) is a well-konwn traditional Chinese medicine used for treatment of rheumatoid arthritis (RA), dermatophytosis and paralysis. Patients with RA are usually secondary to osteoporosi...

Disruption of the aldehyde dehydrogenase 2 gene increases the bone anabolic response to intermittent PTH treatment in an ovariectomized mouse model.

Apr 24, 2020

Aldehyde dehydrogenase 2 (ALDH2) is the enzyme that oxidizes the acetaldehyde produced by alcohol metabolism. This variant not only affects the response to alcohol but is also associated with several ...

Impact of osteoporosis on different type of short-segment posterior instrumentation for thoracolumbar burst fracture - a finite element analysis.

Apr 24, 2020

In Taiwan (my country), the proportion of people 65 years or older is over 14% in 2018, which is known as entering "aged society". More and more thoracolumbar burst fractures in the setting of osteopo...

Simultaneous fluorescence and quantitative phase imaging of MG63 osteosarcoma cells to monitor morphological changes with time using partially spatially coherent light source.

Apr 24, 2020

Quantitative phase imaging (QPI) technique is used to determine various biophysical parameters, such as refractive index, cell thickness, morphology, etc. On the other hand, fluorescence microscopy is...

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