#VisualAbstract: High-dose exercise therapy is not superior to low-dose exercise therapy for knee osteoarthritis
1. In this randomized control trial of knee osteoarthritis patients, there was no significant...
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#VisualAbstract: Moderately accelerated cardiac pacing may be beneficial in patients with heart failure with preserved ejection fraction
1. Quality of life at one year was improved in patients with heart failure with preserved ejection...
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#VisualAbstract: Adjuvant pembrolizumab improves distant metastasis-free survival in stage IIB-C melanoma
Click to read this study in The Lancet Oncology.
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#VisualAbstract: Catheter ablation reduces rates of persistent atrial fibrillation and atrial tachyarrhythmia
1. In patients with untreated paroxysmal atrial fibrillation, catheter ablation was associated...
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#VisualAbstract: Aspirin thromboprophylaxis noninferior to low-molecular-weight heparin in patients with fractures
1. In this randomized clinical trial, there were no differences in mortality, pulmonary embolism,...
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#VisualAbstract: Switch to fulvestrant and palbociclib may improve survival in patients with advanced breast cancer and ESR1 mutation
Click to read this study in The Lancet Oncology.
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#VisualAbstract: Telehealth treatment is effective in managing behavior problems in children with developmental delay
1. In a randomized clinical trial, internet-delivered parent-child interaction therapy (iPCIT)...
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#VisualAbstract: Adagrasib provides antitumour activity against KRAS G12C mutant metastatic colorectal cancer both as monotherapy and in combination with cetuximab
Overall tumour response to monotherapy treatment with adagrasib was 23% 46% in combination with...
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#VisualAbstract: Adjuvant capecitabine improves clinical outcomes in patients with locally advanced nasopharyngeal carcinoma
Click to read this study in JAMA Oncology.
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#VisualAbstract: Tamoxifen increases the risk of endometrial cancer in premenopausal women with breast cancer
Click to read this study in JAMA Network Open.
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#VisualAbstract: Prophylactic methylprednisolone for cardiac surgery in infants does not improve post-operative outcomes
1. In infants undergoing cardiopulmonary bypass surgery, prophylactic methylprednisolone use did...
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#VisualAbstract: Positive prostate MRI and targeted biopsy reduce the detection of clinically insignificant prostate cancer
1. Fewer instances of clinically insignificant prostate cancer were identified in an experimental...
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#VisualAbstract: Smartphone dispatch of volunteer responders may not increase bystander use of automated external defibrillator in out-of-hospital cardiac arrest
1. This randomized controlled trial evaluating the effect of Heartrunner, a smartphone...
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#VisualAbstract: Tumor-infiltrating lymphocyte therapy compared to ipilimumab in advanced melanoma
1 .Tumor-infiltrating lymphocytes therapy shows improvements in PFS when compared to ipilimumab 2....
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#VisualAbstract: Oral antibiotic prophylaxis may reduce incidence of surgical site infections
1. In this randomized controlled trial, oral antimicrobial prophylaxis was reported to reduce the...
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#VisualAbstract: Bepirovirsen may reduce disease burden in patients with chronic hepatitis B
1. Bepirovirsen resulted in a sustained hepatitis B surface antigen (HBsAg) and hepatitis B virus...
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#VisualAbstract: Double sequential external defibrillation and vector-change defibrillation improve outcomes in patients with refractory ventricular fibrillation
1. Compared to standard defibrillation, patients with refractory ventricular fibrillation who...
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#VisualAbstract: Vitamin D supplementation is not preventative for statin-associated muscle symptoms or statin discontinuation
1. A randomized controlled trial found that pretreatment with supplemental vitamin D did not...
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#VisualAbstract: Early mobilization after ICU mechanical ventilation does not improve survival
1. Early mobilization of patients after mechanical ventilation in the intensive care unit (ICU)...
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#VisualAbstract: All-oral regimen with delamanid, linezolid, levofloxacin, and pyrazinamide is effective for fluoroquinolone-sensitive multidrug-resistant tuberculosis
1. At 24 months, treatment success rate was numerically greater in the shorter-regimen group...
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