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Surgery General

TISSUE ENGINEERING IN PLASTIC SURGERY - WHAT HAS BEEN DONE.

Mar 11, 2021

The field of tissue engineering applies principles of engineering and life sciences for the development of functional biologic substitutes. The increasing need of tissue for challenging reconstructive...

The Association between Hospital-Physician Vertical Integration and Outpatient Physician Prices Paid by Commercial Insurers: New Evidence.

Mar 11, 2021

This study assessed the relationship between hospital ownership of physician organizations (known as hospital-physician vertical integration) and facility fees billed to commercial insurers and physic...

Proximal humerus fractures in COVID-19 lockdown: the experience of three orthopedics and traumatology departments in the first ten weeks of the Italian epidemic.

Mar 11, 2021

Coronavirus disease (CoVID-19) is causing millions of deaths worldwide and the crisis of the global healthcare system.  Aim Of The Study: evaluate the preliminary impact of CoVID-19 in three Italian ...

A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement.

Mar 11, 2021

Orthopedic and dental implants made of β-type Ti alloys have low elastic modulus which can better relieve the stress shielding effects after surgical implantation. Nevertheless, clinical application ...

Biologic treatments in Behçet's disease.

Mar 11, 2021

Behçet's disease (BD) significantly increases morbidity and mortality, especially in young men. While vascular involvement is the most frequent cause of mortality, ocular involvement, which can cause...

Improvement in EEG Source Imaging Accuracy by Means of Wavelet Packet Transform and Subspace Component Selection.

Mar 11, 2021

The electroencephalograph (EEG) source imaging (ESI) method is a non-invasive method that provides high temporal resolution imaging of brain electrical activity on the cortex. However, because the acc...

A Survey of the Global Impact of COVID-19 on the Practice of Pediatric Anesthesia: A Study from the Pediatric Anesthesia COVID-19 Collaborative Group.

Mar 11, 2021

Pediatric anesthesiology has been greatly impacted by COVID-19 in the delivery of care to patients and to the individual providers. With this study, we sought to survey pediatric centers and highlight...

Optimizing Motor Intention Detection With Deep Learning: Towards Management Of Intraoperative Awareness.

Mar 11, 2021

This article shows the interest in deep learning techniques to detect motor imagery (MI) from raw electroencephalographic (EEG) signals when a functional electrical stimulation is added or not. Impact...

Nudging patients and surgeons to change ambulatory surgery pain management: Results from an opioid buyback program.

Mar 11, 2021

Optimal postoperative opioid stewardship combines adequate pain medication to control expected discomfort while avoiding abuse and community diversion of unused prescribed opioids. We hypothesized tha...

Hypertonic saline solution decreases oxidative stress in liver hypothermic ischemia.

Mar 11, 2021

Liver ischemia reperfusion injury is still an unsolved problem in liver surgery and transplantation. In this setting, hypothermia is the gold standard method for liver preservation for transplantation...

30 Years of Heart Transplant: Outcomes after Mechanical Circulatory Support from a Single Center.

Mar 08, 2021

Survival after bridge to transplant with mechanical circulatory support (MCS) has yielded varying outcomes based on device type and baseline characteristics Continuous flow left ventricular assist dev...

Navigating Immune Cell Immunometabolism after Liver Transplantation.

Mar 08, 2021

Liver transplantation (LT) is the most effective treatment for end-stage liver diseases. The immunometabolism microenvironment undergoes massive changes at the interface of immune functionalities and ...

Cereblon modulator CC-885 induces CRBN-dependent ubiquitination and degradation of CDK4 in multiple myeloma.

Mar 08, 2021

Molecular glue degraders that hijack cellular E3 ubiquitin ligases to target disease-driven proteins for proteosome-dependent degradation are emerging as a promising treatment. Immunomodulatory drugs ...

Efficacy of microsurgery in treatment of localized or multiple gingival recession: A systematic review.

Mar 08, 2021

To address the clinical question whether microsurgery hold an advantage in terms of clinical and patient oriented outcome over conventional macrosurgical procedures in the treatment of gingival recess...

Aerosol and droplet generation from orbital repair: Surgical risk in the pandemic era.

Mar 08, 2021

The highly contagious COVID-19 has resulted in millions of deaths worldwide. Physicians performing orbital procedures may be at increased risk of occupational exposure to the virus due to exposure to ...

Written Informed Consent-Translating into Plain Language. A Pilot Study.

Mar 08, 2021

Informed consent is important in clinical practice, as a person's written consent is required prior to many medical interventions. Many informed consent forms fail to communicate simply and clearly. T...

Decision curve analysis to evaluate the clinical benefit of prediction models.

Mar 08, 2021

There is increased interest in the use of prediction models to guide clinical decision-making in orthopedics. Prediction models are typically evaluated in terms of their accuracy: discrimination (area...

Perspectives of using Cloud computing in integrative analysis of multi-omics data.

Mar 08, 2021

Integrative analysis of multi-omics data is usually computationally demanding. It frequently requires building complex, multi-step analysis pipelines, applying dedicated techniques for data processing...

The Evidence Base for the Benefits of Functional Septorhinoplasty and its Future Post COVID-19.

Mar 08, 2021

Ever since the introduction of the concept of Procedures of Limited Clinical Value (PoLCV), procedures such as functional septorhinoplasty have been subject to additional funding restrictions within t...

Benefit of postoperative radiotherapy in patients with oropharyngeal squamous cell carcinoma in human papillomavirus (HPV) era: A Surveillance, Epidemiology, and End Results (SEER) database analysis.

Mar 08, 2021

This study aimed to investigate the survival benefit of postoperative radiotherapy in patients with resected human papilloma virus-positive oropharyngeal squamous cell carcinoma using data from the Su...

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