Mar 01, 2021

Little is known about the survival outcomes of and predictive factors for survival in hemodialysis patients undergoing surgery for gastric cancer.We performed a multicenter retrospective study from 9 ...

Mar 01, 2021

Attributable to the high likelihood of developing distant metastatic disease, resection of poorly differentiated gastroenteropancreatic neuroendocrine neoplasms is generally contraindicated. Some pati...

Feb 19, 2021

This study planned to update the previous investigations and researches related to this matter in order to fuse new discoveries. Among preliminaries that evaluated drug classes or methodologies relate...

Feb 19, 2021

This examination planned to evaluate the viability of denosumab and joined with cinacalcet in patients with essential hyperparathyroidism.  Key qualification models were a T-score somewhere in the r...

Feb 19, 2021

In light of the treatment strategy estimand, assessed mean decreases in HbA 1c from gauge (8·3%) to week 52 were −0·9 rate focuses (SE 0·1) with oral semaglutide 3 mg, −1·4 rate focuses (0·1)...

Feb 19, 2021

Gastrointestinal occasions, overwhelmingly of mellow or moderate seriousness, were the most often reported class of adverse event with oral semaglutide: stoppage was generally normal, happening in fiv...

Feb 19, 2021

This study intended to survey the adequacy and security of a hybrid  approach, in which basal insulin conveyance was split among CSII and a day by day infusion of insulin degludec. Individuals were a...

Feb 19, 2021

The aim of this study was to examine associations of maternal thyroid function with birthweight. The study excluded participants with multiple pregnancies, in-vitro fertilisation, pre-existing thyroid...

Feb 19, 2021

This study primarily investigated whether a primarily telehealth lifestyle intervention reduced excess GWG among women with overweight or obesity.Usual antenatal care included an antenatal visit at 7�...

Feb 19, 2021

Type 2 diabetes is influencing individuals at an undeniably more youthful age, especially in the Middle East and in north Africa. The study aimed to survey whether a concentrated way of life mediation...

Feb 19, 2021

Cardiovascular outcome trials have shown cardiovascular benefit with sodium-glucose co-transporter-2 (SGLT2) inhibitors in patients with type 2 diabetes, whereas dipeptidyl peptidase-4 (DPP-4) inhibit...

Feb 19, 2021

SLC16A2 gene encoding monocarboxylate transporter 8 (MCT8), is characterised by intellectual and motor disability resulting from cerebral hypothyroidism and chronic peripheral thyrotoxicosis. We sough...

Feb 19, 2021

This study aimed to examine the kidney effects of the SGLT2 inhibitor dapagliflozin in patients with proteinuric kidney disease without diabetes. Participants  were haphazardly allocated (1:1) to get...

Feb 19, 2021

Maternal overweight and obesity might increase risks of adiposity and cardiovascular and metabolic diseases in offspring. We examined associations between maternal overweight and obesity severity and ...

Feb 18, 2021

Although clinicians often measure the serum concentration of androgens in premenopausal women presenting with sexual dysfunction, with some women given testosterone or dehydroepiandrosterone as treatm...

Feb 18, 2021

Recombinant human growth hormone has been used for more than 30 years and its indications have increased worldwide. There is concern that this treatment might increase mortality, but published data ar...

Feb 18, 2021

The validation of bone mineral density (BMD) as a surrogate outcome for fracture would allow the size of future randomised controlled osteoporosis registration trials to be reduced. We aimed to determ...

Feb 18, 2021

Cross-sectional imaging regularly results in incidental discovery of adrenal tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is hampered by poor specificity of...

Feb 18, 2021

Alkaptonuria is a rare, genetic, multisystem disease characterised by the accumulation of homogentisic acid (HGA). No HGA-lowering therapy has been approved to date. The aim of SONIA 2 was to investig...

Feb 18, 2021

Cushing's disease is a rare endocrine disorder characterised by cortisol overproduction with severe complications. Therapies for cortisol reduction are often necessary. Here we report the outcomes fro...