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Surgery General

Current State of Undergraduate Trauma and Orthopaedics Training in United Kingdom: A Survey-based Study of Undergraduate Teaching Experience and Subjective Clinical Competence in Final-year Medical Students.

Apr 03, 2020

To assess the quality and duration of trauma and orthopedics (T&O) training in medical schools in United Kingdom (UK), and to evaluate final-year students' self-perceived level of competence in essent...

Characterization and Comparison of Human and Ovine Mesenchymal Stromal Cells from Three Corresponding Sources.

Apr 03, 2020

Currently, there is an increasing focus on mesenchymal stromal cells (MSC) as therapeutic option in bone pathologies as well as in general regenerative medicine. Although human MSCs have been extensiv...

[Effect of postoperative hypoalbuminemia and supplement of human serum albumin on the development of poor wound healing following lumbar internal fixation surgery].

Apr 03, 2020

To analyze the association between postoperative hypoalbuminemia and poor wound healing, and to evaluate whether postoperative supplementation of human serum albumin can improve postoperative wound h...

Proper Disposal of Prescription Opioids in Southwest Virginia: Assessment of Patient, Physician, and Medical Student Beliefs and Practices.

Apr 03, 2020

Southwestern Virginia demonstrates the highest regional mortality rate from prescription opioid overdoses. Nationally, 65% of patients misusing opioid medications received them from friends and family...

[Dental malocclusion in children: warning signs].

Apr 03, 2020

WARNING SIGNS. Dental malocclusions are common, and can be dental, skeletal and/or functional. Detecting these pathologies earlier is a signal to remove these causing factors, and act in favor of an h...

Peer-to-Peer Contact Tracing: A Privacy-Preserving Smartphone Application.

Apr 03, 2020

The novel coronavirus disease 2019 (COVID-19) pandemic is an urgent public health crisis, with epidemiologic models predicting severe consequences, including high death rates, if the virus is permitte...

Clotrimazole reduces endometriosis and the estrogen concentration by downregulating aromatase.

Apr 03, 2020

This study aimed to analyse the effects of clotrimazole (CTZ) on estrogen production pathway in endometriosis progression. Experimental endometriosis was induced by autologous transplantation in femal...

A robust and novel electrical impedance metric of pulmonary function in ALS patients.

Apr 03, 2020

Pulmonary function tests (PFTs) are important for assessing respiratory function in amyotrophic lateral sclerosis (ALS) patients. However, weakness of oral and glottal closure, due to concomitant bulb...

Enhanced transcutaneous electrical nerve stimulation achieved by a localized virtual bipole: A computational study of human tibial nerve stimulation.

Apr 03, 2020

Electrical neuromodulation is a clinically effective therapeutic instrument, currently expanding into newer indications and larger patient populations. Neuromodulation technologies are also moving tow...

The Clinical Significance of Seminoma Component in Testicular Mixed Germ Cell Tumour.

Apr 03, 2020

The aim of this study was to examine clinical/pathological characteristics, prognosis and tendency to metastasis of mixed germ cell tumours (MGCTs) that contain a seminoma component.A total of 111 MGC...

Anatomical and radiological features of the bone organization of the anterior part of the mandible.

Apr 03, 2020

The classical anatomical representation of the lingual relief of the mental region of the mandible reflects the presence of geniohyoid as well as genioglossus attachment areas, which are divided into ...

Oncological Outcomes After Anastomotic Leakage After Surgery for Colon or Rectal Cancer: Increased Risk of Local Recurrence.

Apr 03, 2020

The aim of this study was to evaluate oncological outcome for patients with and without anastomotic leakage after colon or rectal cancer surgery.The role of anastomotic leakage in oncological outcome ...

Heavyweight Mesh Is Superior to Lightweight Mesh in Laparo-Endoscopic Inguinal Hernia Repair: A Meta-analysis and Trial Sequential Analysis of Randomized Controlled Trials.

Apr 03, 2020

This meta-analysis and trial sequential analysis aims to provide an update on the available randomized controlled trials (RCTs) and recommendations on using lightweight mesh (LWM) or heavyweight mesh ...

Intraoperative Near-infrared Fluorescence (NIR) Imaging With Indocyanine Green (ICG) Can Identify Bone and Soft Tissue Sarcomas which May Provide Guidance for Oncological Resection.

Apr 03, 2020

Complete excision of sarcomas to maximize function without compromising the oncological outcome can be challenging. The aim of this study was to investigate the feasibility and potential drawbacks of ...

Matched Pairs Comparison of an Enhanced Recovery Pathway Versus Conventional Management on Opioid Exposure and Pain Control in Patients Undergoing Lung Surgery.

Apr 03, 2020

The aim of this study was to assess the effect of an enhanced recovery after surgery (ERAS) pathway on pain and opioid use following lung resection.A major component ERAS pathways is opioid-sparing an...

Quality of Surgery and Outcome in Localized Gastrointestinal Stromal Tumors Treated Within an International Intergroup Randomized Clinical Trial of Adjuvant Imatinib.

Apr 03, 2020

The association between quality of surgery and overall survival in patients affected by localized gastrointestinal stromal tumors (GIST) is not completely understood.To assess the risk of death with a...

Ketamine and nitrous oxide: The evolution of NMDA receptor antagonists as antidepressant agents.

Apr 03, 2020

N-methyl-d-aspartate receptor (NMDAR) antagonists, including ketamine and nitrous oxide, are currently intensely studied as rapid-acting antidepressant agents. Interestingly, both of these compounds a...

Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain.

Apr 03, 2020

Effective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic. Persistent postsurgical pain (PPP) has an inc...

Use of new psychoactive substances to mimic prescription drugs: the trend in France.

Apr 03, 2020

Among the expanding world of New Psychoactive Substances (NPS), Designer Medicines (DM) are designed to mimic psychoactive drugs and might lead to adverse events of various severity. The DM category i...

Antibody avidity-based approach to estimate population-level incidence of hepatitis C.

Apr 03, 2020

Accurate hepatitis C virus (HCV) incidence estimates are critical for monitoring progress towards HCV elimination goals, including an 80% reduction in HCV incidence by 2030. Moreover, incidence estima...

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