Apr 03, 2020

The association between quality of surgery and overall survival in patients affected by localized gastrointestinal stromal tumors (GIST) is not completely understood.To assess the risk of death with a...

Apr 03, 2020

N-methyl-d-aspartate receptor (NMDAR) antagonists, including ketamine and nitrous oxide, are currently intensely studied as rapid-acting antidepressant agents. Interestingly, both of these compounds a...

Apr 03, 2020

Effective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic. Persistent postsurgical pain (PPP) has an inc...

Apr 03, 2020

Among the expanding world of New Psychoactive Substances (NPS), Designer Medicines (DM) are designed to mimic psychoactive drugs and might lead to adverse events of various severity. The DM category i...

Apr 03, 2020

Accurate hepatitis C virus (HCV) incidence estimates are critical for monitoring progress towards HCV elimination goals, including an 80% reduction in HCV incidence by 2030. Moreover, incidence estima...

Mar 26, 2020

While antireflux surgery is often proposed to patients with proton pump inhibitor-refractory GERD, a subgroup of patients remains symptomatic or experiences late complications of surgery, such as dy...

Mar 24, 2020

Children with Down syndrome (DS) often present with chronic respiratory symptoms. Congenital airway anomalies have been described but data about prevalence is scarce and a comparison to controls is la...

Mar 24, 2020

Depression is a common disease that afflicts one in 6 people. Numerous hypotheses have been raised in the past decades, but the exact mechanism for depression onset remains obscure. Recently, the neur...

Mar 24, 2020

Non-medical use of prescription drugs (NMUPD) has become a threat to public health. In the United States, NMUPD is especially common in young adults (aged 18-25). Self-esteem is a robust psychosocial...

Mar 24, 2020

Assess impact of parental involvement in care provision for term substance exposed newborns (SENs).Prospective observational cohort study included mothers with opioid use disorder and their SENs over ...

Mar 24, 2020

The opioid overdose crisis in the United States has prompted an expansion of treatment services, including pharmacotherapy with buprenorphine. However, many people who use illicit opioids (PWUIO) self...

Mar 24, 2020

Medicinal plants from traditional chinese medicine are used increasingly worldwide for their benefits to health and quality of life for the relevant clinical symptoms related to pain. Among them, Salv...

Mar 19, 2020

Prognostic biomarkers of T cell-mediated rejection (TCMR) have not been adequately studied in the modern era. We evaluated 803 renal transplant recipients and correlated HLA-DR/DQ molecular mismatch a...

Mar 19, 2020

Postoperative pain is an outcome of importance to potential living kidney donors. We prospectively characterized the prevalence, severity and patterns of acute or chronic postoperative pain in 193 LKD...

Mar 19, 2020

Exhaustion of T cells limits their ability to clear chronic infections or eradicate tumors. Here, in the context of transplantation, we investigated whether T-cell exhaustion occurs and has a role in ...

Mar 19, 2020

Recurrence of immunoglobulin (Ig)A nephropathy (rIgAN) is a growing cause of kidney allograft dysfunction. This study was aimed at investigating factors associated with rIgAN and the subsequent progre...

Mar 19, 2020

Fifteen to thirty percentage of patients with severe aortic stenosis (AS) have preserved left ventricular ejection fraction (LVEF) and a discordant AS pattern at Doppler echocardiography, which is cha...

Mar 19, 2020

Valve repair for aortic insufficiency (AI) requires a tailored surgical approach determined by the leaflet and aortic disease. In this study, we used a repair-oriented system for the classification of...

Mar 19, 2020

Many adults with repaired tetralogy of Fallot will require a pulmonary valve replacement (PVR), but there is no consensus on the best timing. In this study, we aim to evaluate the impact of age at PVR...

Mar 19, 2020

The aim of this study was to evaluate very long-term results after unrestricted everolimus-eluting bioresorbable scaffolds (BRS) implantation.Previous randomized studies mainly included selected patie...