Mar 10, 2020

The aim of this study was to compare how two innovative laser titanium surfaces and sandblasted and acid-etched surfaces influence human osteoblast behavior during osteogenesis and the initial phases ...

Mar 10, 2020

The objectives of this study were to understand how cadaveric simulation impacts learning in orthopedic residents, why it is a useful training tool, and how skills learnt in the simulated environment ...

Mar 10, 2020

Non-alcoholic fatty liver disease (NAFLD) is characterized by accumulation of excessive triglycerides (TGs) in hepatocytes. Obesity is a major risk factor for developing fatty liver, although the intr...

Mar 10, 2020

ENSURE-AF (NCT02072434) assessed therapy with edoxaban versus enoxaparin-warfarin in patients with nonvalvular atrial fibrillation (AF) undergoing elective electrical cardioversion (ECV).To evaluate c...

Mar 10, 2020

Periodontal disease results from the pathogenic interactions between the tissue, immune system, and microbiota; however, standard therapy fails to address the cellular mechanism underlying the chronic...

Mar 10, 2020

The aim of this nation-wide study was to evaluate the characteristics of bacterial (BI), invasive fungal disease (IFD) and viral infections (VI) in pediatric patients with PID after allogeneic hematop...

Mar 10, 2020

Upfront surgery is the standard treatment for resectable invasive intraductal papillary mucinous carcinoma; however, recurrence is common. Therefore, we investigated the recurrence, surgical outcome, ...

Mar 10, 2020

Establish whether POCD is associated with new disability after surgery, which would inform whether POCD impacts patient-centered outcomes.POCD is a decline in neuropsychiatric tests scores from presur...

Mar 10, 2020

To examine the association between Textbook Outcome (TO)-a new composite quality measurement-and long-term survival in gastric cancer surgery.Single-quality indicators do not sufficiently reflect the ...

Mar 10, 2020

To investigate the long-term effect of flexible duty-hour policies on resident outcomes BACKGROUND:: The Flexibility in Duty Hour Requirements for Surgical Trainees trial showed no significant differe...

Mar 10, 2020

Identification of gene mutations that are indicative of epithelial-mesenchymal transition and a noninflammatory immune phenotype may be important for predicting response to immune checkpoint inhibitor...

Mar 10, 2020

In KEYNOTE-189, first-line pembrolizumab plus pemetrexed-platinum significantly improved overall survival (OS) and progression-free survival (PFS) compared with placebo plus pemetrexed-platinum in pat...

Mar 10, 2020

Interstitial lung disease (ILD) induced by anti-programmed-cell death-1 (PD-1) and anti-PD-ligand 1 (PD-L1) is potentially life-threatening and is a common reason of the discontinuation of therapy. In...

Mar 10, 2020

The aims of this study were to investigate the expression of prolyl 4-hydroxylase subunit alpha-1 (P4HA1) and its relationship with clinicopathological features in lung cancer (LC), breast cancer (BC)...

Mar 10, 2020

The identification of reliable diagnostic and prognostic biomarkers for Parkinson's disease (PD) is urgently needed. Here, we explored the potential use of α-synuclein (α-syn) in plasma neuronal exo...

Mar 10, 2020

Retrospective database study.We sought to investigate trends and risk factors for new onset anxiety and/or depression within six months after elective spine surgery.Surgery represents a stressful expe...

Mar 10, 2020

To evaluate the SUMMIT-07 trial opioid withdrawal results of NKTR-181 (oxycodegol), a new molecular entity mu-opioid receptor agonist.Phase 3, enriched-enrollment, double-blind, randomized-withdrawal ...

Mar 10, 2020

Vertebroplasty is a percutaneous minimally invasive procedure indicated for vertebral collapse pain treatment. Among the known complications of the procedure is the augmented risk of new vertebral fra...

Mar 10, 2020

While primary care clinicians are being trained to use buprenorphine for the treatment of Opioid Use Disorder (OUD) in order to increase access to addiction treatment, it is not known what impact suc...

Mar 10, 2020

Understanding hepatitis C virus (HCV) transmission among people who inject drugs (PWID) is essential for HCV elimination. We aimed to differentiate reinfections from treatment failures and to identify...