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Surgery General

Proteomic and Transcriptomic Approaches for Studying Bone Regeneration in Health and Systemically Compromised Conditions.

Mar 05, 2020

Bone regeneration is a complex biological process, where the molecular mechanisms are only partially understood. In an ageing population, where the prevalence of chronic diseases with an impact on bon...

Employing an ICT-FRET Integration Platform for the Real-Time Tracking of SO2 Metabolism in Cancer Cells and Tumor Models.

Mar 05, 2020

Glutathione (GSH) mediates a wide variety of biological events and human diseases. Although it has been the subject of intense study in recent years, a further understanding of its molecular mechanism...

[Applying Extended Theory of Planned Behavior for Lung Cancer Patients Undergone Pulmonary Resection: Effects on Self-Efficacy for Exercise, Physical Activities, Physical Function, and Quality of Life].

Mar 05, 2020

This study aims to examine the effects of nursing interventions based on the Extended Theory of Planned Behavior (ETPB) regarding self-efficacy for exercise (SEE), physical activity (PA), physical fun...

Challenges of LC-MS/MS ethyl glucuronide analysis in abstinence monitoring of liver transplant candidates.

Mar 02, 2020

Background Urinary ethyl glucuronide (EtG) has emerged as the biomarker of choice for alcohol abstinence monitoring in forensic toxicology and is now used in the listing decision process for liver tra...

Clinical and Procedural Characteristics Predicting Need for Chronotropic Support and Permanent Pacing Post-Heart Transplantation.

Mar 02, 2020

Post-operative bradycardia can complicate orthotopic heart transplantation (OHT). Previous studies suggested donor age, surgical technique as possible risk factors. However, risk factors in the era of...

IMPACT OF TREATMENT PRIOR TO ALLOGENEIC TRANSPLANTATION OF HEMATOPOIETIC STEM CELLS IN PATIENTS WITH MYELODYSPLASTIC SYNDROME: RESULTS OF THE LATIN AMERICAN BONE MARROW TRANSPLANT REGISTRY.

Mar 02, 2020

It has been suggested that bridging therapy with intensive chemotherapy and/or hypomethylating agents followed by hematopoietic stem cell transplantation (HSCT) can be valuable in the treatment of pat...

Biodegradable versus multiple plastic stent implantation in benign biliary strictures: A systematic review and meta-analysis.

Mar 02, 2020

Benign biliary strictures arise mostly from iatrogenic injuries during surgical procedures and various inflammatory causes. Endoscopic placement of multiple plastic stents (MPS) is often regarded as t...

Regional Wait Times for Patients With Nonmelanoma Skin Cancer in Southwestern Ontario.

Mar 02, 2020

Nonmelanoma skin cancer (NMSC) affects many Canadians. Although morbidity and mortality are rare, the burden to patients and the health-care system is significant. This study aims to evaluate current ...

High-Risk Plastic Surgery: An Analysis of 108,303 Cases From the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP).

Mar 02, 2020

There is a lack of large-scale data that examine complications in plastic surgery. A description of baseline rates and patient outcomes allows better understanding of ways to improve patient care and ...

Three-dimensional surface imaging in breast cancer: a new tool for clinical studies?

Mar 02, 2020

Three-dimensional Surface Imaging (3DSI) is a well-established method to objectively monitor morphological changes in the female breast in the field of plastic surgery. In contrast, in radiation oncol...

The applications of machine learning in plastic and reconstructive surgery: protocol of a systematic review.

Mar 02, 2020

Machine learning, a subset of artificial intelligence, is a set of models and methods that can automatically detect patterns in vast amounts of data, extract information and use it to perform various ...

Structure and ingredient-based biomimetic scaffolds combining with autologous bone marrow-derived mesenchymal stem cell sheets for bone-tendon healing.

Mar 02, 2020

Tendon attaches to bone across a robust fibrocartilaginous tissue termed the bone-tendon interface (BTI), commonly injured in the field of sports medicine and orthopedics with poor prognosis. So far, ...

Biology-inspired microphysiological systems to advance medicines for patient benefit and animal welfare.

Mar 02, 2020

The first microfluidic microphysiological systems (MPS) entered the academic scene more than 15 years ago and were considered an enabling technology to human (patho)biology in vitro and, therefore, pr...

Patient knowledge, experiences and preferences regarding retinoblastoma and research: A qualitative study.

Mar 02, 2020

We launched a patient engagement strategy to facilitate research involvement of the retinoblastoma (childhood eye cancer) community in Canada. To inform our strategy, we aimed to uncover the experienc...

Identifying the core attributes of pediatric communication techniques to be taught to anesthetic trainees.

Mar 02, 2020

Anesthetic induction and other procedures performed by anesthetists are potentially stressful for children. Pediatric anesthetists use communication to rapidly establish rapport and engagement with ch...

Effects of inhalation of sevoflurane at different concentrations on TRPV1 in airways of rats at different developmental stages.

Mar 02, 2020

Aim Determine changes in the expressions of the ion channel-TRPV1-and neuropeptides-NKA, NKB, calcitonin gene-related peptide (CGRP), and SP-in 14-, 21-, and 42-day-old rats after inhaling 1.5% and 2....

Impact of intraoperative noise measurement on the surgeon stress and patient outcomes. A prospective, controlled, single-center clinical trial with 664 patients.

Mar 02, 2020

The impact of sound-activated noise meters to decrease the noise level in the operating room is not clear. The aim of this study was to determine whether a sound-activated, visual noise meter would de...

Kidney Disease-Specific Scores and Health Utility of Continuous Ambulatory Peritoneal Dialysis Patients, Automated Peritoneal Dialysis Patients, and Caregivers.

Mar 02, 2020

This study aimed to compare the EuroQol 5-dimension 5-level questionnaire (EQ-5D-5L), the visual analogue scale (VAS), and the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36) score...

Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expression.

Mar 02, 2020

Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the development of tolerance and of opioid-induced hyperalgesia, both limiting the analgesic use of morphine. We e...

Opioid prescriptions in emergency departments: Findings from the 2016 National Hospital Ambulatory Medical Care Survey.

Mar 02, 2020

In the past decade, there has been a rising trend in the emergency department (ED) visits in the US and these visits carry a significant burden of prescription opioids. This study utilized the latest ...

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