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Surgery General

Osteoimmunology: A Current Update of the Interplay Between Bone and the Immune System.

Feb 25, 2020

Immunology, already a discipline in its own right, has become a major part of many different medical fields. However, its relationship to orthopedics and trauma surgery has unfortunately, and perhaps ...

How We Manage Bone Marrow Edema-An Interdisciplinary Approach.

Feb 25, 2020

Bone marrow edema (BME) is a descriptive term for a common finding in magnetic resonance imaging (MRI). Although pain is the major symptom, BME differs in terms of its causal mechanisms, underlying di...

The impact of fellowship type on trends and complications following total shoulder arthroplasty for osteoarthrosis by recently trained board-eligible orthopedic surgeons.

Feb 25, 2020

Total shoulder arthroplasty (TSA) with an anatomic or reverse prosthesis is a commonly used and successful treatment option for many degenerative shoulder conditions. There is an increasing trend towa...

Strategy to improve the mechanical properties of bioabsorbable materials based on chitosan for orthopedic fixation applications.

Feb 25, 2020

Bioabsorbable polymeric fixation devices have been used as an alternative to metallic implants in orthopedics, preventing the stress shielding effect and avoiding a second surgery for implant removal....

Effects of immersive virtual reality therapy on intravenous patient-controlled sedation during orthopaedic surgery under regional anesthesia: A randomized controlled trial.

Feb 25, 2020

Immersive virtual reality (IVR) is a form of distraction therapy that has shown potential as an analgesia and sedation sparing agent. This study assessed the effect of IVR on the self-administered sed...

Multiple sevoflurane exposures don't disturb the T-cell receptor repertoire in infant rhesus monkeys' thymus.

Feb 25, 2020

Multiple surgical procedures and anesthesia increase the risk of the development in children. However, the influence of such exposures on the developing childhood immunity organs is rarely reported.Hi...

The effect of preoperative erector spinae plane vs. paravertebral blocks on patient-controlled oxycodone consumption after video-assisted thoracic surgery: A prospective randomized, blinded, non-inferiority study.

Feb 25, 2020

To investigate the effective analgesia for video-assisted thoracic surgery.In this prospective non-inferiority study, we evaluated the postoperative analgesic effect of preoperative ultrasound-guided ...

Executive Summary of the American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults.

Feb 25, 2020

The aim of this study was to develop evidence-based recommendations for safe, effective and appropriate thyroidectomy.Surgical management of thyroid disease has evolved considerably over several decad...

The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults.

Feb 25, 2020

To develop evidence-based recommendations for safe, effective, and appropriate thyroidectomy.Surgical management of thyroid disease has evolved considerably over several decades leading to variability...

Changes in Smoking Behavior Before and After Gastric Bypass: A 7-year Study.

Feb 25, 2020

To evaluate smoking history and change in smoking behavior, from 1 year before through 7 years after Roux-en-Y gastric bypass (RYGB) surgery, and to identify risk factors for post-surgery smoking.Smok...

Risk of postoperative thromboembolic complication after major digestive surgery in patients receiving antiplatelet therapy: Lessons from more than 3,000 operations in a single tertiary referral hospital.

Feb 25, 2020

Although recent studies have suggested that the continuation of preoperative antiplatelet therapy with aspirin does not affect intraoperative or postoperative bleeding in patients undergoing digestive...

Preoperative patient education and patient preparedness are associated with less postoperative use of opioids.

Feb 25, 2020

Because many patients are first exposed to opioids after general surgery procedures, surgical stewardship for the use of opioids is critical in addressing the opioid crisis. We developed a multi-compo...

High Expression of Krüppel-like Factor 7 Indicates Unfavorable Clinical Outcomes in Patients with Lung Adenocarcinoma.

Feb 25, 2020

Krüppel-like factor 7 (KLF7), which belongs to the KLF family of zinc finger transcription factors, plays a critical role in regulating gene expression. It was reported that KLF7 overexpression was c...

TRAP1 is a predictive biomarker of platinum-based adjuvant chemotherapy benefits in patients with resected lung adenocarcinoma.

Feb 25, 2020

Platinum-based adjuvant chemotherapy after complete resection has become a standard treatment for patients with stage II to IIIA non-small cell lung cancer; however, not all patients exhibit survival ...

Synthesis, biochemical, pharmacological characterization and in silico profile modelling of highly potent opioid orvinol and thevinol derivatives.

Feb 25, 2020

Morphine and its derivatives play inevitably important role in the μ-opioid receptor (MOR) targeted antinociception. A structure-activity relationship study is presented for novel and known orvinol a...

microRNA-422a Inhibits DCC Expression in a Manner Dependent on SNP rs12607853.

Feb 25, 2020

DCC netrin 1 receptor (DCC) affects the structure and function of the dopamine circuitry, which in turn affects the susceptibility to developing addiction. In a previous study, we found that single nu...

The Burden of Platelet Transfusions in Patients With CLD

Feb 23, 2020

Clinical guidelines recommend that patients who undergo invasive procedures have a platelet count level above 50x10^9/L; these guidelines historically have applied to all patients and do not specifica...

Survival After Pediatric Kidney Transplant Drastically Improved

Feb 20, 2020

THURSDAY, Feb. 20, 2020 (HealthDay News) -- There has been an increase in survival after pediatric kidney transplantation since 1970, according to a study published online Feb. 13 in the Clinical Jour...

Turn-in Flap: 10 Years' Experience of a Single Institution in Saudi Arabia.

Feb 18, 2020

Background and objective Cephalic excision of the lateral crus is the most used procedure in rhinoplasty when attempting to make the nasal tip smaller or narrower to improve the definition. However, d...

Auxiliary usage of botulinum toxin A in plastic surgery in China.

Feb 18, 2020

Currently, botulinum toxin A (BTA) is mainly used in the treatment of muscle spasms and in cosmetic procedures, and its cosmetic indications are expanding rapidly. There have been sporadic reports foc...

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