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Surgery General

Evaluating Biventricular Myocardial Velocity and Interventricular Dyssynchrony in Adult Patients During the First Year After Heart Transplantation.

Feb 17, 2020

Magnetic resonance tissue phase mapping (TPM) measures three-directional myocardial velocities of the left and right ventricle (LV, RV). This noninvasive technique may supplement endomyocardial biopsy...

Association between alcohol consumption and subclinical femoral atherosclerosis in smoking and non-smoking men: the AWHS Study.

Feb 17, 2020

Many addictive substances, such as tobacco and alcohol, influence atherosclerosis development. Whether tobacco's pro-atherosclerotic effect is influenced by alcohol consumption is unknown. We aimed to...

Habitual cigarette smoking attenuates shear-mediated dilation in the brachial artery but not in the carotid artery in young adults.

Feb 17, 2020

In the present study, we hypothesized that habitual cigarette smoking attenuates endothelial function in the cerebral circulation as well as that of the peripheral circulation in young adults. To test...

Pathogenesis of obstructive sleep apnea in individuals with the COPD + OSA Overlap syndrome versus OSA alone.

Feb 17, 2020

Overlap syndrome (OVS) is the concurrence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), and is associated with poor outcomes. We hypothesized that physiological ch...

Modeling Combination HCV Treatment and Prevention Strategies in a Network of People Who Inject Drugs in the USA.

Feb 17, 2020

HCV treatment as prevention (TasP) strategies can contribute to HCV micro-elimination, yet complimentary interventions like opioid agonist therapies (OAT) and syringe services programs (SSP) may impro...

Safety aspects of opioid-naïve patients with high-grade glioma treated with D,L-Methadone: an observational case series.

Feb 17, 2020

It was suggested that D, L-Methadone might improve the clinical course of glioma patients. Owing to massive press coverage, patients demand the prescription of D, L-Methadone, but regarding its adjunc...

A randomised, double-blind, crossover, dose ranging study to determine the optimal dose of oral opioid to treat breakthrough pain for patients with advanced cancer already established on regular opioids.

Feb 17, 2020

Pain in people with advanced cancer is prevalent. When a stable dose of opioids is established, people still experience episodic breakthrough pain for which dosing of an immediate release opioid is us...

Associations between Neighborhood-Level Factors and Opioid-Related Mortality: A Multilevel Analysis using Death Certificate Data.

Feb 17, 2020

To identify associations between opioid-related mortality and neighborhood-level risk factors.Cross-sectional study.Massachusetts, USA.Using 2011-2014 Massachusetts death certificate data, we identifi...

Serum exosomal miR-378 upregulation is associated with poor prognosis in non-small-cell lung cancer patients.

Feb 17, 2020

Deregulated circulating microRNAs (miRNAs) are potential biomarkers for the early detection and prognosis prediction of non-small-cell lung cancer (NSCLC). The aim of the present study was to investig...

The preoperative platelet distribution width: A predictive factor of the prognosis in patients with non-small cell lung cancer.

Feb 17, 2020

The prognostic value of platelet distribution width (PDW) is different in various malignancies. The purpose of this study was to identify the relationship between preoperative PDW and survival in pati...

Predictive value of CD73 expression for the efficacy of immune checkpoint inhibitors in NSCLC.

Feb 17, 2020

CD73 induces the dephosphorylation of adenosine monophosphate converting it to adenosine, enabling malignancies to escape from immune surveillance. Although CD73 overexpression has been reported to be...

Cone-beam CT radiomics features might improve the prediction of lung toxicity after SBRT in stage I NSCLC patients.

Feb 17, 2020

Stereotactic body radiotherapy (SBRT) is the standard care for inoperable early stage non-small cell lung cancer (NSCLC). The purpose of our study was to investigate whether a prediction model based o...

Impact of resection margin status on survival in pancreatic cancer patients after neoadjuvant treatment and pancreatoduodenectomy.

Jan 30, 2020

Resection margin status has been recognized as an independent prognostic factor on overall survival in pancreatic cancer patients undergoing surgical resection. However, its impact after neoadjuvant t...

Burden of emergency pediatric surgical procedures on surgical capacity in Uganda: a new metric for health system performance.

Jan 27, 2020

The significant burden of emergency operations in low- and middle-income countries can overwhelm surgical capacity leading to a backlog of elective surgical cases. The purpose of this investigation wa...

Laparoscopic Liver Transplantation: Dream or Reality? The First Step With Laparoscopic Explant Hepatectomy.

Jan 27, 2020

To introduce the laparoscopic approach in liver transplant recipients.Despite the increasingly frequent use of laparoscopy in living donor hepatectomy, the laparoscopic approach has never been reporte...

Consensus Statement on Robotic Mastectomy-Expert Panel From International Endoscopic and Robotic Breast Surgery Symposium (IERBS) 2019.

Jan 27, 2020

To achieve a consensus statement on robotic mastectomy.Robotic-assisted surgery has gained much attention especially the results of few case series reporting on the technical feasibility, safety and e...

Perceptions on gender disparity in surgery and surgical leadership: A multicenter mixed methods study.

Jan 27, 2020

Our objective was to identify perceptions of the environment for women in surgery among 4 academic institutions.Faculty surgeons and senior surgery residents were randomly selected to participate in a...

Emerging microbiology diagnostics for transplant infections: On the cusp of a paradigm shift.

Jan 24, 2020

In light of the heightened risk for infection associated with solid organ and hematopoietic stem cell transplantation, rapid and accurate microbiology diagnostics are essential to the practice of tran...

Neoadjuvant Chemoradiotherapy and Liver Transplantation for Unresectable Hilar Cholangiocarcinoma: The Irish Experience of the Mayo Protocol.

Jan 24, 2020

Pioneered by the Mayo Clinic, multimodal therapy with neoadjuvant chemoradiotherapy and orthotopic liver transplant has emerged as a promising option for unresectable hilar cholangiocarcinoma. This st...

Novel Organ Perfusion and Preservation Strategies in Transplantation - where are we going in the UK?

Jan 24, 2020

This review article focuses on current clinical outcomes with novel perfusion strategies in organ transplantation. Broadly, these approaches can be divided into in-situ regional perfusion in the donor...

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