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Surgery General

Surgical Prevention of Anastomotic Recurrence by Excluding Mesentery in Crohn's Disease: The SuPREMe-CD Study - A Randomized Clinical Trial.

Feb 18, 2020

MINI: In this randomized clinical trial to prevent anastomotic recurrence in Crohn disease, the new Kono-S anastomosis demonstrates a significant reduction in postoperative clinical and endoscopic rec...

Clinical Effectiveness of the Elder-Friendly Approaches to the Surgical Environment Initiative in Emergency General Surgery.

Feb 18, 2020

Older adults, especially those with frailty, have a higher risk for complications and death after emergency surgery. Acute Care for the Elderly models have been successful in medical wards, but little...

Association Between Use of Enhanced Recovery After Surgery Protocol and Postoperative Complications in Total Hip and Knee Arthroplasty in the Postoperative Outcomes Within Enhanced Recovery After Surgery Protocol in Elective Total Hip and Knee Arthroplasty Study (POWER2).

Feb 18, 2020

The Enhanced Recovery After Surgery (ERAS) care protocol has been shown to improve outcomes compared with traditional care in certain types of surgery.To assess the association of use of the ERAS prot...

Liver Transplantation for Alcoholic Liver Disease: What Is the Risk and Consequence of Relapse?

Feb 18, 2020

Although short- and medium-term outcomes after liver transplantation for alcohol-related liver disease (ARLD) are generally excellent and similar to outcomes for transplantation for other indications,...

Should ACE inhibitors or calcium channel blockers be used for post-transplant hypertension?

Feb 18, 2020

Arterial hypertension in renal transplant recipients warrants antihypertensive treatment. The preferable choice of antihypertensives that should be used in patients after kidney transplantation remain...

Synthetic hair reactions and treatment of complications: Case reports.

Feb 18, 2020

Synthetic hair fiber implantation first achieved widespread use in the 1970s, but in 1983, the US Federal Drug Administration banned the fibers due to its complications. Currently available synthetic ...

Role of molecular biomarkers in liver transplantation for hepatocellular carcinoma.

Feb 18, 2020

Patient selection and organ allocation for liver transplantation (LT) in patients with hepatocellular carcinoma (HCC) relies predominantly on clinical parameters, such as tumor burden (i.e., radiologi...

Evaluating Biventricular Myocardial Velocity and Interventricular Dyssynchrony in Adult Patients During the First Year After Heart Transplantation.

Feb 17, 2020

Magnetic resonance tissue phase mapping (TPM) measures three-directional myocardial velocities of the left and right ventricle (LV, RV). This noninvasive technique may supplement endomyocardial biopsy...

Association between alcohol consumption and subclinical femoral atherosclerosis in smoking and non-smoking men: the AWHS Study.

Feb 17, 2020

Many addictive substances, such as tobacco and alcohol, influence atherosclerosis development. Whether tobacco's pro-atherosclerotic effect is influenced by alcohol consumption is unknown. We aimed to...

Habitual cigarette smoking attenuates shear-mediated dilation in the brachial artery but not in the carotid artery in young adults.

Feb 17, 2020

In the present study, we hypothesized that habitual cigarette smoking attenuates endothelial function in the cerebral circulation as well as that of the peripheral circulation in young adults. To test...

Pathogenesis of obstructive sleep apnea in individuals with the COPD + OSA Overlap syndrome versus OSA alone.

Feb 17, 2020

Overlap syndrome (OVS) is the concurrence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), and is associated with poor outcomes. We hypothesized that physiological ch...

Modeling Combination HCV Treatment and Prevention Strategies in a Network of People Who Inject Drugs in the USA.

Feb 17, 2020

HCV treatment as prevention (TasP) strategies can contribute to HCV micro-elimination, yet complimentary interventions like opioid agonist therapies (OAT) and syringe services programs (SSP) may impro...

Safety aspects of opioid-naïve patients with high-grade glioma treated with D,L-Methadone: an observational case series.

Feb 17, 2020

It was suggested that D, L-Methadone might improve the clinical course of glioma patients. Owing to massive press coverage, patients demand the prescription of D, L-Methadone, but regarding its adjunc...

A randomised, double-blind, crossover, dose ranging study to determine the optimal dose of oral opioid to treat breakthrough pain for patients with advanced cancer already established on regular opioids.

Feb 17, 2020

Pain in people with advanced cancer is prevalent. When a stable dose of opioids is established, people still experience episodic breakthrough pain for which dosing of an immediate release opioid is us...

Associations between Neighborhood-Level Factors and Opioid-Related Mortality: A Multilevel Analysis using Death Certificate Data.

Feb 17, 2020

To identify associations between opioid-related mortality and neighborhood-level risk factors.Cross-sectional study.Massachusetts, USA.Using 2011-2014 Massachusetts death certificate data, we identifi...

Serum exosomal miR-378 upregulation is associated with poor prognosis in non-small-cell lung cancer patients.

Feb 17, 2020

Deregulated circulating microRNAs (miRNAs) are potential biomarkers for the early detection and prognosis prediction of non-small-cell lung cancer (NSCLC). The aim of the present study was to investig...

The preoperative platelet distribution width: A predictive factor of the prognosis in patients with non-small cell lung cancer.

Feb 17, 2020

The prognostic value of platelet distribution width (PDW) is different in various malignancies. The purpose of this study was to identify the relationship between preoperative PDW and survival in pati...

Predictive value of CD73 expression for the efficacy of immune checkpoint inhibitors in NSCLC.

Feb 17, 2020

CD73 induces the dephosphorylation of adenosine monophosphate converting it to adenosine, enabling malignancies to escape from immune surveillance. Although CD73 overexpression has been reported to be...

Cone-beam CT radiomics features might improve the prediction of lung toxicity after SBRT in stage I NSCLC patients.

Feb 17, 2020

Stereotactic body radiotherapy (SBRT) is the standard care for inoperable early stage non-small cell lung cancer (NSCLC). The purpose of our study was to investigate whether a prediction model based o...

Impact of resection margin status on survival in pancreatic cancer patients after neoadjuvant treatment and pancreatoduodenectomy.

Jan 30, 2020

Resection margin status has been recognized as an independent prognostic factor on overall survival in pancreatic cancer patients undergoing surgical resection. However, its impact after neoadjuvant t...

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