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Surgery General

Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves.

Feb 12, 2024

Macrophage recruitment to the injured nerve initiates a cascade of events, including myelin debris clearance and nerve trophic factor secretion, which contribute to proper nerve tissue repair. However...

Effect of Lower Extremity Nerve Decompression in Patients with Painful Diabetic Peripheral Neuropathy: The DNND Randomized, Observation Group- and Placebo Surgery-controlled Clinical Trial.

Feb 12, 2024

Evaluate the effect of nerve decompression on pain in patients with lower extremity painful Diabetic Peripheral Neuropathy (DPN).Currently, no treatment provides lasting relief for patients with DPN. ...

"The Equipoise Ruler:" A National Survey on Surgeon Judgment about the Value of Surgery.

Feb 12, 2024

The objective of this study was to understand professional norms regarding the value of surgery.Agreed-upon professional norms may improve surgical decision making by contextualizing the nature of sur...

Parodontgel® on Wound Healing and Patient-Reported Outcome Measures (PROMs) after Tunneled Coronally Advanced Flap (TCAF).

Feb 05, 2024

The adjunctive use of healing gels following periodontal plastic surgery is not common in clinical practice, and no definitive benefits have yet been demonstrated. . A 33-year-old male patient with a ...

Bilobed Flap Coverage for the Reconstruction of Dorsal Soft Tissue Defect Over the Proximal Phalanx: A Case Report.

Feb 05, 2024

Soft tissue defects over the dorsal finger are common and may result from trauma, burns, or surgical management of infections and tumors. We present a case where a bilobed flap was used for the recons...

A modified frailty index predicts complication, readmission, and 30-day mortality following the revision total hip arthroplasty.

Feb 05, 2024

This study aimed to develop a modified frailty index (MFI) to predict the risks of revision total hip arthroplasty (THA).Data from the American College of Surgeons - National Surgical Quality Improvem...

Xinshubao tablet rescues cognitive dysfunction in a mouse model of vascular dementia: Involvement of neurogenesis and neuroinflammation.

Feb 05, 2024

Vascular dementia (VaD) represents a severe cognitive dysfunction syndrome closed linked to cardiovascular function. In the present study, we assessed the potential of Xinshubao tablet (XSB), a tradit...

Targeted local anesthesia: a novel slow-release FeO-lidocaine-PLGA microsphere endowed with a magnetic targeting function.

Feb 05, 2024

Lidocaine microspheres can prolong the analgesic time to 24-48 h, which still cannot meet the need of postoperative analgesia lasting more than 3 days. Therefore, we added FeO to the lidocaine micros...

Postoperative Hyperamylasemia (POH) is an Early Predictor of Pancreatic Fistula Occurrence and Severity after Distal Pancreatectomy: Results from a European Multicentric Study.

Feb 05, 2024

The aim of this international multicentric study is to characterize postoperative hyperamylasemia (POH) after distal pancreatectomy (DP), with particular focus on its relationship with postoperative p...

Minimally invasive pancreaticoduodenectomy: A favorable approach for frail patients with pancreatic cancer.

Feb 05, 2024

Within the past decade, minimally invasive pancreaticoduodenectomy has been increasingly adopted in high-volume cancer centers. Amid broader trends of a growing older population, the numbers of frail ...

Investigation of Circular RNA Expression Profiles in Ultrasound-guided Incomplete Radiofrequency Ablation Transplanted Tumor Models of Human Liver Cancer.

Jan 29, 2024

Abnormally expressed circular RNAs (circRNAs) are associated with many diseases and have important biological effects on the regulation of gene expression. However, the circRNA expression profile in i...

Depression, Anxiety, Body Dissatisfaction, and Eating Disorders in Plastic Surgery Patients.

Jan 29, 2024

This study aimed to identify and describe indicators of depression, anxiety, body dissatisfaction, and risk of an eating disorder in patients who undergo plastic surgery.The sample was made up of 90 p...

Examining Racial and Gender Diversity in the Plastic Surgery Pipeline: Where is the Leak?

Jan 29, 2024

There is limited information about minority representation throughout the plastic and reconstructive surgery (PRS) pipeline. The aim of this study was to examine trends in representation among minorit...

Analgesic Techniques for Managing Orthopedic Injuries: A Review for the Emergency Clinician.

Jan 29, 2024

Orthopedic injuries are commonly managed in the emergency department (ED) setting. Fractures and dislocations may require reduction for proper management. There are a variety of analgesic and sedative...

Predictors of adequate pain control after outpatient hand and upper extremity surgery.

Jan 29, 2024

The opioid epidemic has changed practice, though there remains a paucity of data regarding prescribing habits and pain control following outpatient hand surgery. We sought to evaluate patient-related ...

The CSF1-CSF1R pathway in the trigeminal ganglion mediates trigeminal neuralgia via inflammatory responses in mice.

Jan 29, 2024

Trigeminal neuralgia (TN) is the most severe type of neuropathic pain. The trigeminal ganglion (TG) is a crucial target for the pathogenesis and treatment of TN. The colony-stimulating factor 1 (CSF1)...

Clinical Efficacy of Laparoscopic Sentinel Node Navigation Surgery for Stomach Preservation in Patients With Early Gastric Cancer: 5-year Results of the SENORITA Trial.

Jan 29, 2024

This study aimed to compare laparoscopic standard gastrectomy (LSG) and laparoscopic sentinel node navigation surgery (LSNNS) for EGC in terms of 5-year long-term oncologic outcomes.The oncological sa...

Microbiome Dysbiosis with Enterococcus Presence in the Upper Gastrointestinal Tract is A Risk Factor for Mortality in Patients Undergoing Surgery for Pancreatic Cancer.

Jan 29, 2024

Recent retrospective studies suggest a role for distinct microbiota in the perioperative morbidity and mortality of pancreatic head resections.We aimed to prospectively investigate the microbial colon...

Incidence of formation of anti-D between patients with and without a history of solid organ transplant.

Jan 22, 2024

Solid organ transplant surgeries including liver transplants constitute a substantial risk of bleeding complications and given frequent national blood shortages, supporting D-negative transplant recip...

Application of Fixation of Orbicularis Oculi Muscle and Orbital Septal Tissue Flap at the Upper Edge of Incision in Double Eyelid Plasty.

Jan 22, 2024

In order to make the postoperative effect of open double eyelid more close to the physiological and anatomical structure of double eyelid, we improved the traditional open double eyelid operation acco...

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