Jul 29, 2021

Diabetes is a leading cause of foot ulcers and lower limb amputation throughout the world. Adequate wound debridement and cover is the standard of care, but lack of adequate vascularised local tissue ...

Jul 29, 2021

The techniques used to repair bilateral cleft lip have evolved over time, yet little data exist to compare outcomes using the various techniques. The aim of this study was to retrospectively evaluate ...

Jul 29, 2021

The discipline of orthopedics and trauma surgery strives for constant improvement of the quality of results in arthroplasty; however, in order to enable targeted alterations to the establish standard ...

Jul 29, 2021

Hyaluronic Acid (HA) is a glycosaminoglycan widely used in the fields of orthopedics, ophthalmology, and aesthetic medicine due to its significant ability to reduce the synthesis of pro-inflammatory p...

Jul 29, 2021

Lateral fractures of proximal femur are the most frequent to treat for the traumatologist surgeon. Intramedullary nailing is the gold standard treatment of this type of fracture. The aim of the study ...

Jul 29, 2021

The coronavirus disease 2019 (COVID-19) outbreak has been declared a global pandemic of unprecedented proportions. Italy is a country which has been heavily affected. Cancer patients are at a higher r...

Jul 29, 2021

Radiofrequency ablation is an alternative strategy for the management of benign thyroid conditions. We analyzed the proportion of patients who underwent thyroid surgery for benign conditions who would...

Jul 29, 2021

To determine if simulation training is required to pass the Fundamentals of Endoscopic Surgery (FES) skills test and assess the relationship between simulation training, clinical training, and FES ski...

Jul 29, 2021

Surgeons are traditionally categorized as working either in academic or private/community practice, but some transition between the two environments. Here, we profile current academic cardiothoracic s...

Jul 28, 2021

This study states that The activity of immune checkpoint inhibitors (ICI) against NSCLC brain metastases is unknown. We compared CNS outcomes between ICI- and chemo-treated patients who have received...

Jul 28, 2021

his study states that Optimal second-line chemotherapy for patients with relapsed small-cell lung cancer remains debatable. In addition to topotecan or amrubicin monotherapy, re-challenge with first-l...

Jul 28, 2021

This study states that Circulating tumor cells (CTCs) are associated with tumor spread, whereas cancer stem cells may be related to drug resistance. However, few studies have analyzed the levels of ci...

Jul 28, 2021

This study states that First-line (1L) immunotherapy (I-O) has improved outcomes in patients with advanced non-small cell lung cancer (NSCLC) in clinical trials and is now routinely used alone or comb...

Jul 28, 2021

This study clearly depicts that Lung cancer screening eligibility determined by Health Technology Assessment (HTA) and MISCAN microsimulation model vs. PLCOm2012 model. PLCOm2012 had significantly hig...

Jul 28, 2021

This study states that Despite extensive effort, the search for clinically-relevant metabolite biomarkers for early detection, disease monitoring, and outcome prediction in lung cancer remains unfulfi...

Jul 28, 2021

Limited information is available on the appropriate treatment duration of immune checkpoint inhibitors (ICIs). We aimed to identify candidates who would benefit from ICI discontinuation after one year...

Jul 28, 2021

The aim is To microsimulate the effects of three additional annual CT screening rounds on lung cancer (LC) survival in the National Lung Screening Trial (NLST). We used multiple imputation to model t...

Jul 28, 2021

Our study provides a unique insight in the decision making in the setting of COVID-19 outbreak. A treatment strategy modification after COVID-19 outbreak was made for 32 % of patients. Treatment modif...

Jul 28, 2021

The aim of this study is For NSCLC with biopsy suggestive of in situ disease, 49.3 % had invasion at resection.Size and squamous histology were significantly associated with risk of invasion. Even les...

Jul 28, 2021

The incidence of lymph node metastases in thymoma remains unclear. Surgical complications of lymph node dissection are rare. Systematic lymph node dissection did not increase the rate of N positive tu...