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Orthopedics

Comparison of the effectiveness of different machine learning algorithms in predicting new fractures after PKP for osteoporotic vertebral compression fractures.

Jan 23, 2023

The use of machine learning has the potential to estimate the probability of a second classification event more accurately than traditional statistical methods, and few previous studies on predicting ...

A real-world study of treatment patterns among patients with osteoporotic fracture: analysis of a Japanese hospital database.

Jan 23, 2023

Health records of patients hospitalized for osteoporotic fracture were analyzed. Prior to the index hospital admission, most patients were not receiving any antiosteoporotic treatment. During the inde...

Impaction grafting of lumbar pedicle defects: a biomechanical study of a novel technique for pedicle screw revision.

Jan 23, 2023

The two most common revision options available for the management of loose pedicle screws are larger-diameter screws and cement augmentation into the vertebral body for secondary fixation. An alternat...

Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice.

Jan 23, 2023

Glucagon-like peptide-2 (GLP-2) is secreted postprandially by enteroendocrine L-cells and stimulates growth of the gut and bone. One GLP-2 analogue is approved for short bowel syndrome (SBS). To impro...

Fracture Risk Up With Higher Levels of HDL-C in Healthy Seniors

Jan 20, 2023

THURSDAY, Jan. 19, 2023 (HealthDay News) -- For older adults, higher levels of high-density lipoprotein cholesterol (HDL-C) are associated with increased fracture risk, according to a study published ...

Outcome After Treatment of Distal Fibula Fractures Using One-Third Tubular Plate, Locking Compression Plate or Distal Anatomical Locking Compression Plate.

Jan 16, 2023

Surgical treatment of lateral distal fibula fractures is associated with high risk of reoperation and complications. The primary aim was to report risks of surgical site infection (SSI) and reoperatio...

Failure modes after anterior cruciate ligament reconstruction: a systematic review and meta-analysis.

Jan 16, 2023

The reason for graft failure after anterior cruciate ligament reconstruction (ACLR) is multifactorial. Controversies remain regarding the predominant factor and incidence of failure aetiology in the l...

The Integrator complex desensitizes cellular response to TGF-β/BMP signaling.

Jan 16, 2023

Maintenance of stem cells requires the concerted actions of niche-derived signals and stem cell-intrinsic factors. Although Decapentaplegic (Dpp), a Drosophila bone morphogenetic protein (BMP) molecul...

The prevalence of headshaking in horses with primary and secondary dental sinusitis and computed tomographic evidence of infraorbital canal pathology.

Jan 16, 2023

Sinusitis is a common disease of horses yet there are a limited number of reports in the literature that describe the prevalence of infraorbital canal (IOC) pathology and headshaking behaviour in hors...

Inpatient Mortality Up With Exposure to High Capacity Utilization

Jan 14, 2023

FRIDAY, Jan. 13, 2023 (HealthDay News) -- For inpatients, exposure to high bed-occupancy (capacity utilization) increases the risk of mortality, according to a study published online Dec. 19 in BMC He...

Older Knee Replacement Implants as Good as Newer Models

Jan 13, 2023

THURSDAY, Jan. 12, 2023 (HealthDay News) -- Older knee replacement implants are as good as newer models for total knee replacement (TKR), according to a study published in the January issue of BMJ Ope...

Three in 10 Adults With Chronic Pain Use Cannabis to Manage Condition

Jan 11, 2023

TUESDAY, Jan. 10, 2023 (HealthDay News) -- Three in 10 adults with chronic pain in states with medical cannabis laws report using cannabis to manage their pain, according to a study published online J...

Letter Intervention Ups Prescription Monitoring Program Engagement

Jan 11, 2023

TUESDAY, Jan. 10, 2023 (HealthDay News) -- A simple letter intervention highlighting a new mandate to check the prescription monitoring program (PMP) before prescribing controlled substances, with or ...

Auditory rehabilitation after temporal bone fracture with cochlea implants - a case control study.

Jan 09, 2023

Temporal bone fracture can cause posttraumatic deafness. Sequelae like ossification or obliteration of the cochlea can impact the outcome of cochlea implantation. This study highlights the effect of ...

Effects of surgical factors on the outcomes of zygoma reduction malarplasty: a quantitative computed tomography study.

Jan 09, 2023

Malarplasty is widely performed for zygoma reduction. The effects of body segmentation, plate bending, and postoperative arch location on zygomatic movement have not been analyzed using computed tomog...

Faster Recovery Seen With Unicompartmental Knee Arthroplasty

Jan 07, 2023

FRIDAY, Jan. 6, 2023 (HealthDay News) -- For patients with isolated medial knee osteoarthritis, unicompartmental knee arthroplasty (UKA) yields faster functional recovery than total knee arthroplasty ...

ACP Updates Living Guideline on Pharmacologic Treatment of Osteoporosis

Jan 04, 2023

TUESDAY, Jan. 3, 2023 (HealthDay News) -- In a living clinical guideline issued by the American College of Physicians (ACP) and published online Jan. 3 in the Annals of Internal Medicine, updated reco...

PCP-Specialist Cotraining Improves Patient Experiences

Jan 04, 2023

TUESDAY, Jan. 3, 2023 (HealthDay News) -- Primary care physician (PCP)-specialist cotraining yields changes in specialist care that improve patient experiences, according to a study published online J...

Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression.

Jan 02, 2023

Fibroblast activation protein (Fap) is a serine protease that degrades denatured type I collagen, α2-antiplasmin and FGF21. Fap is highly expressed in bone marrow stromal cells and functions as an os...

Effect of Abaloparatide on Bone Microarchitecture Assessed by Trabecular Bone Score in Women with Osteoporosis: Post Hoc Analysis of ACTIVE and ACTIVExtend.

Jan 02, 2023

Although bone mineral density (BMD) is a predictor of fracture, many fractures occur in women with T-scores >-2.5. Bone microarchitecture, assessed by trabecular bone score (TBS), predicts fracture...

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