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BPH/LUTS

Inhibition of integrin receptors reduces extracellular matrix levels, ameliorating benign prostate hyperplasia.

Sep 04, 2023

Although a high prevalence of benign prostate hyperplasia (BPH) has been documented, the risk factors are poorly understood. Metabolic syndrome increases the risk of BPH. Succinylation, a type of post...

A scoping review of risk factors for urinary incontinence in older men.

Sep 04, 2023

Most epidemiological studies have not systematically identified or categorized risk factors for urinary incontinence (UI) in older men, despite a higher prevalence than in younger men. Considering the...

Nicotine perturbs the microbiota of brown planthopper (Nilaparvata lugens stål Hemiptera: Delphinidae).

Aug 28, 2023

Bacterial symbionts exhibiting co-evolutionary patterns with insect hosts play a vital role in the nutrient synthesis, metabolism, development, reproduction, and immunity of insects. The brown plantho...

Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas' disease.

Aug 28, 2023

Trypanosoma cruzi is the causative agent of Chagas' disease, an endemic and neglected disease. The treatment is limited to only two drugs, benznidazole (BZL) and nifurtimox (NFX), introduced more than...

Effects of Unripe Black Raspberry Extract Supplementation on Male Climacteric Syndrome and Voiding Dysfunction: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial.

Aug 14, 2023

Male climacteric syndrome (MCS) is a medical condition that can affect middle-aged men whose testosterone levels begin to decline considerably. These symptoms may include fatigue, decreased libido, mo...

Aquablation® in patients on antithrombotics: Assessment of safety, post-operative bleeding rates and clinical outcomes.

Aug 14, 2023

To analyze the impact of perioperative antithrombotic use on the bleeding outcomes following Aquablation.116 men with who underwent Aquablation as part of the WATER prospective trial (NCT02505919) wer...

Kisspeptin Is Upregulated at the Maternal-Fetal Interface of the Preeclamptic-like BPH/5 Mouse and Normalized after Synchronization of Sex Steroid Hormones.

Aug 07, 2023

Insufficient invasion of conceptus-derived trophoblast cells in the maternal decidua is a key event in the development of early-onset preeclampsia (PE), a subtype of PE associated with high maternal a...

Pelvic floor dysfunction and obesity.

Aug 07, 2023

Obesity is a growing condition within the society and more patients, who have underlying obesity, are presenting with lower urinary tract symptoms (LUTS) and pelvic floor dysfunction (PFD). The effect...

Efficacy and safety of the TENSI+ device for posterior tibial nerve stimulation: A multicenter, retrospective study.

Jul 31, 2023

Transcutaneous posterior tibial nerve stimulation (TC-PTNS) is a validated option for lower urinary tract symptoms (LUTS) management, with a short-term success rate of around 60% and few adverse event...

Holmium Laser Enucleation of the Prostate Versus Transvesical Single-Port Robotic Simple Prostatectomy for Large Prostatic Glands.

Jul 31, 2023

To compare the perioperative outcomes of transvesical single-port robotic simple prostatectomy (SP-RASP) and holmium laser enucleation of the prostate (HoLEP).A retrospective review was performed of p...

Treatment patterns in men prescribed benign prostatic obstruction or overactive bladder medications in Canada: a retrospective population-based study.

Jul 17, 2023

To characterize first therapeutic change and healthcare resource utilization in older men initiating an overactive bladder or benign prostatic obstruction medication.A retrospective cohort study using...

Water vapor thermal therapy: technical variations among spanish hospitals and efficacy at 2-year follow-up.

Jul 10, 2023

The aim of this work is to evaluate the initial experience with water vapor thermal therapy (WVTT) for benign prostatic hyperplasia (BPH) in Spanish university hospitals, as well as to describe the di...

Outcomes of holmium laser enucleation of the prostate (HoLEP) for very large-sized benign prostatic hyperplasia (over 150 mL): open simple prostatectomy is dead.

Jul 03, 2023

Our study aimed to describe the outcomes of transurethral enucleation of the prostate (HoLEP) for large-sized benign prostatic hyperplasia over 150 mL (bBPH).We conducted a retrospective, descriptive...

Jasmonate-mediated gibberellin catabolism constrains growth during herbivore attack in rice.

Jul 03, 2023

Plant defense against herbivores is costly and often associated with growth repression. The phytohormone jasmonate (JA) plays a central role in prioritizing defense over growth during herbivore attack...

Risk Factors for Persistent Lower Urinary Tract Symptoms One Month Following Convective Water Vapor Thermal Therapy (CWVTT-Rezum).

Jun 26, 2023

To investigate the incidence and risk factors of persistent lower urinary tract symptoms (LUTS) one month and later following convective water vapor thermal therapy (CWVTT) in men with LUTS secondary ...

Durable benefit after treatment of obstructive benign prostatic hyperplasia with a novel drug-device combination product: 2-year outcomes from the EVEREST-I study.

Jun 26, 2023

To evaluate the safety and efficacy of the Optilume BPH Catheter System for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).This open-label, single...

The decline in transurethral resection of the prostate gland in Irish public hospitals between 2005 and 2021.

Jun 19, 2023

Lower urinary tract symptoms due to an enlarged prostate is a common condition. Transurethral resection of the prostate gland (TURP) has been the gold standard treatment. The objective of this study w...

N-Butyl Cyanoacrylate Glue Versus Nonspherical Polyvinyl Alcohol Particles For Prostatic Arterial Embolization To Treat Benign Prostatic Hyperplasia: Safety And Efficacy.

Jun 19, 2023

Our aim is to compare N-butyl cyanoacrylate (NBCA) glue and non-spherical polyvinyl alcohol (PVA) particles for prostatic artery embolization (PAE) for patients with benign prostatic hyperplasia (BPH)...

Is it time to reconsider how we document pediatric uroflow studies?: A study from the SPU Voiding Dysfunction task force.

Jun 12, 2023

Uroflowmetry is a non-invasive study used in the diagnosis and monitoring of treatment response for lower urinary tract disorders. For optimal clinical utility, uroflow studies rely on careful clinica...

Development and validation of models predicting treatment patterns in women with urinary urgency and/or urgency incontinence: A Symptoms of Lower Urinary Tract Dysfunction Research Network observational cohort study.

Jun 05, 2023

To develop a tool to predict a woman's treatment pattern for bothersome urinary urgency (UU) and/or UU incontinence over 1 year after presenting for care at urology or urogynecology clinics.The Sympto...

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