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Urology General

RNA-sequencing profiling analysis of pericyte-derived extracellular vesicle-mimetic nanovesicles-regulated genes in primary cultured fibroblasts from normal and Peyronie's disease penile tunica albuginea.

Aug 09, 2021

Peyronie's disease (PD) is a severe fibrotic disease of the tunica albuginea that causes penis curvature and leads to penile pain, deformity, and erectile dysfunction. The role of pericytes in the pat...

Robotic-Assisted vs. Open Simple Prostatectomy for Large Prostates: A Meta-Analysis.

Aug 09, 2021

To compare the efficacy and safety of robotic-assisted simple prostatectomy and open simple prostatectomy for large benign prostatic hyperplasia. We systematically searched the Cochrane Library, Pub...

Curcumin attenuates prostatic hyperplasia caused by inflammation up-regulation of bone morphogenetic protein and activin membrane-bound inhibitor.

Aug 09, 2021

Inflammation and epithelial-mesenchymal transition (EMT) play important roles in the occurrence and development of benign prostatic hyperplasia (BPH); curcumin exerts anti-proliferative, anti-inflamma...

The UroLift implant: mechanism behind rapid and durable relief from prostatic obstruction.

Aug 09, 2021

Benign prostatic hyperplasia (BPH) is an affliction of the aging male population that contributes to bothersome and disruptive lower urinary tract symptoms (LUTS). The UroLift® implant has been devel...

Penile Pain in Men With Peyronie’s Disease: Identifying Prevalence & Predictors

Aug 05, 2021

Men with Peyronie’s disease (PD) typically present with complaints of penile deformity, but some patients also report suffering from pain and erectile dysfunction (ED). “There is a common misconc...

Correlations between bladder wall thickness and clinical manifestations in female patients with detrusor underactivity and detrusor overactivity-with-detrusor underactivity.

Aug 05, 2021

Among female patients with lower urinary tract symptoms, detrusor underactivity (DU) and detrusor overactivity-with-detrusor underactivity (DO-DU) are two common diagnoses. Here, we investigated the c...

The Environmental Role of Hydration in Kidney Health and Disease.

Aug 05, 2021

Clinical Background: Hydration status, which is influenced by environment and self-behavior is associated with kidney health and disease. Epidemiology: Lack of safe water, sanitation, and high tempera...

Prospective analysis over time of semen parameters in spinal cord-injured patients: results of a pilot study.

Aug 05, 2021

Spinal cord injury (SCI) often results in erectile dysfunction and anejaculation along with impaired semen parameters. Fertility is a major concern in SCI adult males and some fear that the delay post...

Comorbidities Among Sexual Problems in Men: Results From an Internet Convenience Sample.

Aug 05, 2021

Men suffering from one sexual problem sometimes report having another sexual problem, but few studies have determined concordance rates among dysfunctions in non-clinical samples.This study determined...

Spinal versus general anesthesia for Holmium laser enucleation of the prostate of high-risk patients - A propensity-score-matched-analysis.

Aug 05, 2021

To compare perioperative management and functional outcome of spinal anesthesia (SpA) to general anesthesia (GA) in high-risk patients treated for lower urinary tract symptoms (LUTS) with Holmium lase...

Effects of inflammatory prostatitis on the development and progression of benign prostatic hyperplasia: A literature review.

Aug 05, 2021

Benign prostatic hyperplasia is a major disease that affects the quality of life of middle-aged and older men. Although >70% of men aged >70 years have pathological benign prostatic hyperplasia...

Prostate interventions in patients with mild haemophilia: Safe and feasible.

Aug 05, 2021

To date, there is no specific recommendation or evaluation of the morbidity of prostate surgery in patients with haemophilia (PWH) although this surgery is common and at high risk of bleeding.To asses...

Patients' perspective on shared decision-making in urology: a prospective study at a university hospital.

Aug 05, 2021

This study aims to determine the degree of shared decision-making (SDM) from urological patients' perspective and to identify possible predictors.Overall, 469 urological patients of a university outpa...

Demographic Differences and Disparities in the Misdiagnosis of Interstitial Cystitis/Bladder Pain Syndrome in a National Cohort of VA Patients.

Aug 05, 2021

To explore association between misdiagnosis of IC/BPS and demographics. Interstitial cystitis/bladder pain syndrome (IC/BPS) is associated with significant diagnostic uncertainty, resulting in frequen...

Kidney disease profile and encountered problems during follow-up in Syrian refugee children: a multicenter retrospective study.

Aug 02, 2021

Children are one of the most vulnerable groups in conflict zones, especially those with chronic diseases. This study aimed to investigate kidney disease profiles and problems during follow-up in a pop...

Safety of autologous bone marrow-derived mesenchymal stem cells in erectile dysfunction: an open-label phase 1 clinical trial.

Aug 02, 2021

The efficacy of phosphodiesterase type 5 inhibitors (PDE5Is), which are commonly used to treat erectile dysfunction (ED), is not satisfactory in patients with denervation of the cavernous nerve due to...

Culture and purification of SD rat corpus cavernosum endothelial cells by enzymatic digestion combined with mechanical extrusion and fixed-point digestion.

Aug 02, 2021

To explore a new method of in vitro culture and purification of rat corpus cavernosum endothelial cells (CCECs). Male Sprague-Dawley rats' penile tissue were digested with elastase or collagenase comb...

Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs.

Aug 02, 2021

Sexual health has a fundamental role in overall health and well-being, and a healthy and dynamic sex life can make an important contribution to a good quality of life. Sexual dysfunction, and especial...

High Level of Phosphatidylcholines/Lysophosphatidylcholine Ratio in Urine is Associated with Prostate Cancer.

Aug 02, 2021

The altered levels of phospholipids (PLs) and lysophospholipids (LPLs) in prostate cancer (CaP) and benign tissues in our previous findings prompted us to explore PLs and LPLs as potential biomarkers ...

Global, Regional, and National Incidence and Year Lived with Disability for Benign Prostatic Hyperplasia from 1990 to 2019.

Aug 02, 2021

The objective of this study is to provide comprehensive and up-to-date estimates on the disease burden of BPH in 204 countries and territories between 1990 and 2019. Data about incidence, year lived w...

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