The following is a summary of “Longitudinal Change of Cup to Disc Ratio in Premature Infants with Enlarged Cup to Disc Ratio and Normal Intraocular Pressure,” published in the October 2023 issue of Opthalmology by Kim et al.
Researchers started a retrospective study to evaluate the longitudinal change in cup-to-disc ratio (CDR) in premature infants with large CDR and normal intraocular pressure (IOP).
They conducted a retrospective, observational study that involved 283 eyes of 283 premature infants at a single center. The infants were categorized into enlarged CDR and control groups. Data regarding demographics, gestational age (GA), birth weight (BW), vertical cup-to-disc ratio (vCDR), IOP, and corneal diameter were examined.
The results showed 283 patients and 38 (13.4%) were in the enlarged CDR group, while 245 (86.6%) were in the control group. In the enlarged CDR group, the vertical CDR (vCDR) and baseline IOP were 0.63 ± 0.12 and 12.7 ± 2.2 mmHg, respectively. In the control group, the vCDR and baseline IOP were 0.18 ± 0.05 and 10.9 ± 1.7 mmHg, respectively. The IOP at a GA of 40 weeks and 1 and 2 years of age significantly decreased compared to the baseline. There were no significant differences in vCDR between the baseline and each follow-up visit, vCDR showed negative but insignificant correlations with GA and BW.
Investigators concluded that vCDR remained unchanged at 2 years in premature infants with enlarged CDR and normal IOP, but close follow-up is needed.
Source: tandfonline.com/doi/abs/10.1080/08820538.2023.2264381
