Alcohol misuse contributes to global cognitive deficits in people with HIV, particularly those aged 50 and older, according to results published in Alcoholism Clinical And Experimental Research. Scott Edwards, PhD, and colleagues examined relationships between alcohol use and cognition in 259 underserved patients with HIV (66.7% men; mean age, 52). The average Montreal Cognitive Assessment (MoCA) score was 20.7±4.5, with 86.5% demonstrating cognitive impairment (MoCA < 26). Patients with MoCA scores below 18, indicating moderate or severe cognitive impairment, had a greater rate of recent severe alcohol misuse and greater lifetime alcohol consumption. Participants at increased risk for alcohol use disorders (Alcohol Use Disorders [AUD] Identification Test score, ≥16) also had poorer global cognition and memory task performance, especially those aged 50 and older. An analysis of the MoCA sub-score data showed that participants with increased AUD risk had impairments in the cognitive domains of language and memory