Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Machine Learning System Makes More Alerts for Med Errors

TUESDAY, Dec. 31, 2019 (HealthDay News) — A machine learning system can generate clinically valid alerts for medication errors that might be missed with existing clinical decision support (CDS) systems, according to a study published in the January issue of The Joint Commission Journal on Quality and Patient Safety.

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MIV-711 No Better Than Placebo for Pain Relief in Knee OA

TUESDAY, Dec. 31, 2019 (HealthDay News) — A novel cathepsin K inhibitor, MIV-711, is no more effective than placebo for reducing pain in patients with symptomatic, radiographic knee osteoarthritis, according to a study published online Dec. 31 in the Annals of Internal Medicine.

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Inflammation Linked to Thyroid Dysfunction in Psoriasis Patients

MONDAY, Dec. 30, 2019 (HealthDay News) — While the rate of thyroid dysfunction among patients with psoriasis generally is not higher than expected, psoriasis in patients with thyroid dysfunction is more clinically severe and serum levels of C-reactive protein (CRP) are higher, according to a study published online Dec. 5 in the Journal of Dermatology.

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Multiple Health Benefits Reported for Intermittent Fasting

MONDAY, Dec. 30, 2019 (HealthDay News) — Intermittent fasting has multiple health benefits, according to a review article published in the Dec. 26 issue of the New England Journal of Medicine.

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High Lipoprotein(a) Is Risk Factor for CVD in Type 1 Diabetes

MONDAY, Dec. 30, 2019 (HealthDay News) — For patients with type 1 diabetes, lipoprotein(a) [Lp(a)] is a significant risk factor for macrovascular disease, albuminuria, and calcified aortic valve disease, according to a study published online Dec. 20 in Diabetes Care.

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Gastric Sleeve Tied to Lower Risk for Subsequent Procedures

MONDAY, Dec. 30, 2019 (HealthDay News) — Patients undergoing vertical sleeve gastrectomy (VSG) appear to be less likely than matched patients undergoing Roux-en-Y gastric bypass (RYGB) to experience subsequent abdominal operative interventions, according to a study published online Dec. 18 in JAMA Network Open.

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Poor Diet Contributes Substantially to Cardiometabolic Disease Costs

MONDAY, Dec. 30, 2019 (HealthDay News) — Suboptimal diet accounts for 18.2 percent of all cardiometabolic disease (CMD) costs in the United States, according to a study published online Dec. 17 in PLOS Medicine.

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Liposuction Benefits Women With Lipedema

FRIDAY, Dec. 27, 2019 (HealthDay News) — Liposuction improves the quality of life for women with lipedema, according to a study published in the December issue of Plastic and Reconstructive Surgery.

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Bariatric Surgery in Teens May Cut Diabetic Kidney Disease Risk

FRIDAY, Dec. 27, 2019 (HealthDay News) — Among obese adolescents with type 2 diabetes, metabolic bariatric surgery is associated with decreased rates of hyperfiltration and elevated urinary albumin excretion (UAE), according to a study published in the January issue of Diabetes Care.

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Many Hospitals Fail to Provide Instructions for Patient Portals

THURSDAY, Dec. 26, 2019 (HealthDay News) — Many hospital patient portals fail to educate patients fully and set expectations for secure messaging, according to a study recently published in the Journal of General Internal Medicine.

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Diabetes Prevalence Varies by Race, Ethnicity

THURSDAY, Dec. 26, 2019 (HealthDay News) — The prevalence of diabetes and undiagnosed diabetes varies by race/ethnicity and among subgroups within the adult Hispanic and non-Hispanic Asian populations, according to a study published in the Dec. 24/31 issue of the Journal of the American Medical Association.

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Palliative Care Services Lagging Worldwide

TUESDAY, Dec. 24, 2019 (HealthDay News) — Greater palliative care development and implementation is needed worldwide, according to a study recently published in the Journal of Pain and Symptom Management.

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Prenatal Smoking Raises Risk for Gestational Diabetes Mellitus

TUESDAY, Dec. 24, 2019 (HealthDay News) — Prenatal smoking is associated with higher odds of gestational diabetes mellitus, even after adjusting for other known risk factors, according to a study published in the January issue of Obstetrics & Gynecology.

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Patient Share of Out-of-Network Costs Rising

TUESDAY, Dec. 24, 2019 (HealthDay News) — The out-of-pocket costs for out-of-network (OON) care grew rapidly for privately insured Americans from 2012 to 2017, according to a study published in the December issue of the American Journal of Managed Care.

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Endocrine Society Releases Hypoglycemia Performance Measures

TUESDAY, Dec. 24, 2019 (HealthDay News) — A new set of quality measures can help health care providers identify older adults with type 2 diabetes who are at increased risk for hypoglycemia, according to an article published online Dec. 11 in the Journal of Clinical Endocrinology & Metabolism.

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U.S. Incidence of Thyroid Cancer Plateaued in 2009

TUESDAY, Dec. 24, 2019 (HealthDay News) — From 2009 to 2016, the incidence of thyroid cancer reached a plateau and possibly started to decline, according to a research letter published in the Dec. 24/31 issue of the Journal of the American Medical Association.

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Enrollment in Affordable Care Act Holds Steady for Third Straight Year

MONDAY, Dec. 23, 2019 (HealthDay News) — Enrollment in Affordable Care Act coverage for next year has surpassed 8 million, a sign that many Americans still turn to the government health insurance program to help pay for their medical care.

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Age at Obesity Onset Tied to Risk for Type 2 Diabetes in Women

MONDAY, Dec. 23, 2019 (HealthDay News) — The age of onset of obesity and cumulative exposure to obesity are associated with the risk for type 2 diabetes, according to a study published online Dec. 20 in Diabetologia.

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Infertility Risk Increased for Men Born Small for Gestational Age

MONDAY, Dec. 23, 2019 (HealthDay News) — Men born small for gestational age (SGA) may have an increased risk for infertility in adulthood, according to a study published online Dec. 13 in Human Reproduction.

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Overt Hypothyroidism May Up All-Cause Mortality in the Elderly

MONDAY, Dec. 23, 2019 (HealthDay News) — Hypothyroidism is significantly associated with increased all-cause mortality, but not cardiovascular mortality, among the elderly, according to a review published online Dec. 12 in the Journal of Clinical Endocrinology & Metabolism.

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Congress Approves Raising Age to Buy Tobacco Products to 21

FRIDAY, Dec. 20, 2019 (HealthDay News) — A measure to raise the minimum age to buy tobacco and electronic cigarettes to 21 has been approved by the U.S. Congress and is expected to be signed into law by President Donald Trump.

The New York Times Article

Vitamin D Supplementation Alone May Not Reduce Fracture Risk

FRIDAY, Dec. 20, 2019 (HealthDay News) — Supplementation with vitamin D alone does not appear to reduce the risk for fracture, according to a review published online Dec. 20 in JAMA Network Open.

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HbA1c Minimally Adds to CVD Risk Prediction in Prediabetes

FRIDAY, Dec. 20, 2019 (HealthDay News) — For individuals with prediabetes, hemoglobin A1c (HbA1c) minimally adds to cardiovascular disease (CVD) risk prediction, according to a study published online Dec. 18 in Diabetes Care.

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Private Care Program for U.S. Vets Gets $8.9 Billion in Budget Deal

THURSDAY, Dec. 19, 2019 (HealthDay News) — A controversial program meant to get more U.S. veterans to use private health care received $8.9 billion as part of a government spending bill approved by the House.

AP News Article

T2DM Risk Cut With Weight Loss Even in Nonoverweight People

THURSDAY, Dec. 19, 2019 (HealthDay News) — Losing weight is consistently associated with reduced type 2 diabetes risk across body mass index (BMI), family history, and genetic risk categories, according to a study published online Dec. 10 in PLOS Medicine.

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Obesity Projected to Affect Almost One in Two by 2030

WEDNESDAY, Dec. 18, 2019 (HealthDay News) — Nearly half of adults are projected to have obesity by 2030, according to a study published in the Dec. 19 issue of the New England Journal of Medicine.

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FDA to Allow States to Import Prescription Drugs From Other Countries

WEDNESDAY, Dec. 18, 2019 (HealthDay News) — Federal health officials have unveiled plans to allow prescription drug imports from Canada and other foreign nations.

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Refined Carbs May Up Insomnia Risk in Postmenopausal Women

WEDNESDAY, Dec. 18, 2019 (HealthDay News) — Diets with a higher glycemic index (GI) may be a risk factor for insomnia in postmenopausal women, according to a study published online Dec. 11 in the American Journal of Clinical Nutrition.

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FDA Approves Sale of Low-Nicotine Cigarettes

TUESDAY, Dec. 17, 2019 (HealthDay News) — The U.S. Food and Drug Administration on Tuesday approved the sale of two reduced-nicotine cigarettes.

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Congress Could Raise Age to Buy Tobacco Products to 21

TUESDAY, Dec. 17, 2019 (HealthDay News) — A provision to raise the U.S. minimum age to buy tobacco products from 18 to 21 years has been inserted into the end-of-year spending bill in Congress.

CBS News Article

Hospital-Level Home Acute Care Can Cut Costs, Health Care Use

TUESDAY, Dec. 17, 2019 (HealthDay News) — For acutely ill adults, hospital-level care at home is associated with reduced costs, health care use, and readmissions compared with usual hospital care, according to a study published online Dec. 17 in the Annals of Internal Medicine.

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Consuming Ultraprocessed Food May Up Risk for Type 2 Diabetes

MONDAY, Dec. 16, 2019 (HealthDay News) — Ultraprocessed food (UPF) consumption is associated with an increased risk for type 2 diabetes (T2D), according to a study published online Dec. 16 in JAMA Internal Medicine.

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Outcomes Worse for Rural Residents With Chronic Conditions

MONDAY, Dec. 16, 2019 (HealthDay News) — Rural Medicare beneficiaries with complex chronic conditions have higher preventable hospitalization and mortality rates than their urban peers, which is partially explained by reduced access to specialists, according to a report published in the December issue of Health Affairs, a theme issue on rural health.

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Five-Year Mortality Up in Older Adults With Unplanned Admission

MONDAY, Dec. 16, 2019 (HealthDay News) — Death within five years of first unplanned hospital admission is common among older adults, according to a study published in the Dec. 16 issue of CMAJ, the journal of the Canadian Medical Association.

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Hahn Confirmed as New FDA Chief

FRIDAY, Dec. 13, 2019 (HealthDay News) — Stephen Hahn, M.D., was confirmed as commissioner of the U.S. Food and Drug Administration in a 72-18 Senate vote on Thursday.

The New York Times Article

Moderate Physical Activity Tied to Lower Fasting GLP-1 in Men

FRIDAY, Dec. 13, 2019 (HealthDay News) — For overweight men, physical activity (PA) even at moderate intensity is associated with lower fasting and greater glucose-stimulated glucagon-like peptide-1 (GLP-1) responses, according to a study published online Dec. 1 in Endocrine Connections.

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Antibiotics Often Prescribed Without Documented Indication

THURSDAY, Dec. 12, 2019 (HealthDay News) — A considerable proportion of antibiotics are prescribed without a documented indication, according to a study published online Dec. 11 in The BMJ.

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Labeling Exercise Needed to Burn Food May Cut Calories Consumed

THURSDAY, Dec. 12, 2019 (HealthDay News) — Labeling foods, drinks, and menus with the amount and type of exercise needed to burn off the calories might be a more effective way of encouraging people to make healthier dietary choices, according to a review published online Dec. 10 in the Journal of Epidemiology & Community Health.

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Type 2 Diabetes More Common in Patients With Psoriasis

WEDNESDAY, Dec. 11, 2019 (HealthDay News) — Rates of type 2 diabetes may be higher among patients with psoriasis, according to a study published online Dec. 3 in the Journal of the European Academy of Dermatology and Venereology.

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Strength Training Tied to Less Weight Loss-Induced Bone Loss

TUESDAY, Dec. 10, 2019 (HealthDay News) — Both resistance and combined aerobic and resistance exercise are associated with less weight loss-induced bone loss than aerobic exercise alone, according to a study published online Dec. 4 in the Journal of Bone and Mineral Research.

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U.S. Primary Care Doctors Face Challenges in Coordinating Care

TUESDAY, Dec. 10, 2019 (HealthDay News) — Physicians from the United States and other high-income countries report difficulties with care coordination, with a substantial proportion of U.S. physicians not receiving timely notification or the information needed from specialists or other sites of care, according to a study published online Dec. 10 in Health Affairs.

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Many With Diabetes Engage in Underground Exchange of Medications, Supplies

TUESDAY, Dec. 10, 2019 (HealthDay News) — Patients with diabetes frequently engage in underground exchange activities for medications and supplies, according to a study published online Dec. 4 in the Journal of Diabetes Science and Technology.

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U.S. Health Care Spending Up 4.6 Percent in 2018

TUESDAY, Dec. 10, 2019 (HealthDay News) — In 2018, U.S. health care spending increased 4.6 percent, a faster rate than that seen in 2017, according to a report published online Dec. 5 in Health Affairs.

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Low-Dose Aspirin May Cut Dementia Risk in Women With Diabetes

TUESDAY, Dec. 10, 2019 (HealthDay News) — Long-term use of low-dose aspirin may reduce the risk for dementia in women with type 2 diabetes, according to a study published online Dec. 4 in Diabetes Care.

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2016 to 2019 Saw Increase in Medical Students With Disabilities

MONDAY, Dec. 9, 2019 (HealthDay News) — From 2016 to 2019, there was an increase in the proportion of medical students reporting disabilities, according to a research letter published in the Nov. 26 issue of the Journal of the American Medical Association.

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Half of U.S. Physicians Recommend Complementary Health Approaches

MONDAY, Dec. 9, 2019 (HealthDay News) — More than half of office-based physicians recommend complementary health approaches (CHAs) to their patients, according to a study published online Dec. 2 in the Journal of Alternative and Complementary Medicine.

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Retail Prescription Drug Prices Fall for First Time in 45 Years

FRIDAY, Dec. 6, 2019 (HealthDay News) — Retail prescription drug prices in the United States fell by 1 percent last year, a new government report shows.

AP News Article

FDA Testing Levels of Carcinogen in Diabetes Drug Metformin

FRIDAY, Dec. 6, 2019 (HealthDay News) — Levels of possible cancer-causing chemicals in metformin diabetes medications are under investigation by the U.S. Food and Drug Administration.

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Rural Population Underrepresented Among Medical Students

FRIDAY, Dec. 6, 2019 (HealthDay News) — In 2017, less than 5 percent of all incoming medical students were rural students, according to a study published in the December issue of Health Affairs, a theme issue on rural health.

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Preterm Birth May Increase Risk for Diabetes Into Adulthood

FRIDAY, Dec. 6, 2019 (HealthDay News) — Preterm birth is associated with an increased risk for type 1 and type 2 diabetes from childhood into early and middle adulthood, according to a study published online Dec. 3 in Diabetologia.

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Pharmacist-Led Interventions Cut Cardiovascular Risk Factors

FRIDAY, Dec. 6, 2019 (HealthDay News) — Pharmacist-led interventions in general practice can significantly reduce medical risk factors associated with cardiovascular events, according to a review published online Nov. 27 in the British Journal of Clinical Pharmacology.

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Services Affected by Rural Hospitals Joining Health Systems

WEDNESDAY, Dec. 4, 2019 (HealthDay News) — While affiliating with health systems may boost a rural hospital’s financial viability, the affiliation is often associated with reductions in critical services, according to a study published in the December issue of Health Affairs, a theme issue on rural health.

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Adults Not Living in Metro Areas Have Reduced Access to Care

WEDNESDAY, Dec. 4, 2019 (HealthDay News) — Adults not living in metropolitan statistical areas (MSAs) are more likely to have reduced access to or use of health care services, according to a study published online Dec. 4 in the National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Physician Depressive Symptoms Tied to Higher Risk for Medical Errors

WEDNESDAY, Dec. 4, 2019 (HealthDay News) — Physicians showing depressive symptoms are at higher risk for medical errors, according to a review published Nov. 27 in JAMA Network Open.

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T1DM May Up Progression of CAC During Menopausal Transition

TUESDAY, Dec. 3, 2019 (HealthDay News) — For women going through menopause, type 1 diabetes is associated with higher coronary artery calcium (CAC) volume and accelerated progression of CAC over time, according to a study published in the December issue of Diabetes Care.

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Prediabetes Prevalent in U.S. Adolescents, Young Adults

MONDAY, Dec. 2, 2019 (HealthDay News) — The prevalence of prediabetes is high in U.S. adolescents and young adults, according to a study published online Dec. 2 in JAMA Pediatrics.

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Fracture Risk Increased in Adults With Atopic Eczema

MONDAY, Dec. 2, 2019 (HealthDay News) — Patients with atopic eczema have an increased risk for fracture, especially major osteoporotic fractures, according to a study published online Nov. 19 in the Journal of Allergy and Clinical Immunology.

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Risk for Hospital Admission Up With Short-Term PM2.5 Exposure

MONDAY, Dec. 2, 2019 (HealthDay News) — Short-term exposure to fine particulate matter with diameter less than 2.5 µm (PM2.5) is associated with increased hospital admission risks and costs, according to a study published online Nov. 27 in The BMJ.

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Child Consumption of Sugary Drinks Down From 2003 to 2014

MONDAY, Dec. 2, 2019 (HealthDay News) — Efforts to decrease sugar-sweetened beverage consumption during the past decade have been successful, according to a study published online Nov. 20 in the American Journal of Preventive Medicine.

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