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The following is a summary of “Evaluation of Small Vessel Bifurcation Stenting Using the Double-Kissing Culotte and Culotte Technique in Acute Coronary Syndrome: 12-Month Clinical Outcomes,” published in the November 2024 issue of Cardiology by Barycki et al.
Patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for small vessel bifurcation lesions face higher risks of adverse outcomes.
Researchers conducted a retrospective study to evaluate the outcomes of double-kissing (DK) culotte stenting compared to culotte stenting in patients with ACS and small vessel bifurcations.
They analyzed data from the Lower Silesia Culotte Bifurcation Registry to compare outcomes of DK culotte (n = 49) and culotte stenting (n = 52) techniques in patients with small vessel bifurcation lesions (branch diameter ≤2.75 mm). The primary endpoint was target lesion failure (TLF), a composite of cardiovascular death, target vessel myocardial infarction (TVMI), or clinically driven target lesion revascularization (TLR) at 12 months.
The results showed lower TLF rates in the DK culotte group compared to the culotte group (8.2% vs. 19.2%; P=0.082). Clinically driven TLR occurred in 6.1% vs. 13.5% (P=0.161), stent restenosis in 4.1% vs. 9.6% (P=0.203), and major adverse cardiac events (MACE) in 18.4% vs. 25% (P=0.344).
They concluded that DK culotte stenting may offer lower TLF and AE rates than culotte stenting in small vessel bifurcations, but further research is needed to confirm these findings.